-
Research and Development Scientist
1 week ago
Xtalic Marlborough, United StatesXtalic Corporation, a dynamic, growing Boston-area technology company, develops and commercializes electroplating processes for new and novel nanostructured metal alloys based on Massachusetts Institute of Technology (MIT)-developed technology. We are seeking a talented lab scien ...
-
Research And Development Associate
5 days ago
Integrated Resources, Inc ( IRI ) Cambridge, United StatesJob Title: Research and Development Associate III · Location: Cambridge, MA · Duration: 06 months · Job Description: · We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics efforts within our department of Bioth ...
-
Research And Development Scientist
5 days ago
GForce Life Sciences Cambridge, United StatesAssociate Scientist · Duration: 6-month contract · Location: Cambridge, MA · Description: · We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics efforts within our department of Biotherapeutic and Medicinal Scien ...
-
Manager, Development Systems and Research
1 week ago
United Way of Massachusetts Bay, Inc Boston, MA, United StatesUNITED WAY OF MASSACHUSETTS BAY AND MERRIMACK VALLEY · Job Description · United Way of Massachusetts Bay & Merrimack Valley is committed to hiring individuals who reflect the diversity of our communities. · LOCATION: Boston, Attleboro, or Beverly, MA · POSITION TITLE: Manag ...
-
United Way of Massachusetts Bay Boston, United StatesJob Description · Job DescriptionUNITED WAY OF MASSACHUSETTS BAY AND MERRIMACK VALLEY · Job Description · United Way of Massachusetts Bay & Merrimack Valley is committed to hiring individuals who reflect the diversity of our communities. · LOCATION: Boston, Attleboro, or Bever ...
-
Research and Development Manager- Bakery
1 week ago
77 Consultants Boston, United StatesJob Description · Job DescriptionThe role of the R&D Manager is crucial in leading research activities and managing scientists who are dedicated to developing and supporting plant-based ingredients. · The Research and Development team is focused on discovering and developing ingr ...
-
Research Associate, Analytical Development
4 days ago
Garuda Therapeutics, Inc. Cambridge, United StatesGaruda Therapeutics is pioneering the development of off-the-shelf hematopoietic stem cell (HSC)-based cellular therapies for treating patients with blood, bone marrow, immune, and metabolic disorders. The company uses state-of-the-art technologies in developmental biology, gene- ...
-
Research and Development Associate III
6 days ago
Integrated Resources, Inc Cambridge, United StatesJob Title: Research and Development Associate III · Location: Cambridge, MA · Duration: 6+ Months · Job Description: · 100% Onsite in Cambridge, MA · Position Description:We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and b ...
-
Research Associate, Analytical Development
5 days ago
Garuda Therapeutics, Inc. Cambridge, United StatesJob Description · Job DescriptionGaruda Therapeutics is pioneering the development of off-the-shelf hematopoietic stem cell (HSC)-based cellular therapies for treating patients with blood, bone marrow, immune, and metabolic disorders. The company uses state-of-the-art technologie ...
-
Research and Development Associate III
1 week ago
Integrated Resources, Inc Cambridge, United StatesJob Description · Job DescriptionJob Title: Research and Development Associate III · Location: Cambridge, MA · Duration: 6+ Months · Job Description: · 100% Onsite in Cambridge, MA · Position Description:We are looking for a highly motivated Associate Scientist to join our small ...
-
Research and Development Associate III
1 week ago
Integrated Resources, Inc Cambridge- Onsite, United States100% Onsite in Cambridge, MA · Position Description: We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics efforts within our department of Biotherapeutic and Medicinal Sciences as a contract role for 6 months. The ...
-
Research Proposal Development Administrator
1 week ago
Smithsonian Astrophysical Observatory Cambridge, United StatesJob Description · Job DescriptionDescriptionOPENING DATE: May 9, 2024 · CLOSING DATE: June 8, 2024 · SERIES/GRADE: · TYPE OF POSITION: Trust Indefinite (Non-Federal) · DIVISION: Research Administrative Services · LOCATION: Cambridge, MA · AREA OF CONSIDERATION: This position i ...
-
RPM ReSearch Boston, United StatesJob Description · Job DescriptionJob Description · Job Title: Business Development Director · Location: Boston Regional. · Job Summary: The Director of Business Development will have the responsibility for growing, maintaining, and fostering sales in a regional territory.They wil ...
-
Research Development
1 week ago
Innova Solutions Waltham, United States ContractInnova Solutions is immediately hiring for a Scientific Technician · Position Type: Full Time, Contract · Duration: : 12 Months · Location: Waltham, MA · Shift/Schedule :Monday-Friday, 8am-5pm · As a Scientific Technician, your responsibilities: · Description: · We are looking fo ...
-
Vaxess Technologies Cambridge, United StatesLocation: Cambridge, MA · Vaxess Technologies is developing next generation vaccines and therapies based on its proprietary MIMIXTM Microneedle Array Patch technology. MIMIXTM enables self-administration of vaccines and therapeutics to the skin with potential for improved shelf- ...
-
Beam Therapeutics Inc. Cambridge, United StatesPosition Overview: · We are seeking an energetic scientist with broad experience in the development of analytical methods for mRNA, gRNA, pDNA, and mAb platforms. The successful candidate will have deep understanding of analytical control strategy, CMC, product lifecycles, analyt ...
-
Clinical Research Associate II, Clinical Development
22 hours ago
Kisbee Therapeutics Cambridge, United StatesCOMPANY OVERVIEW · Kisbee Therapeutics is an early-stage, venture-backed biotech startup that is targeting apolipoproteins to develop novel therapeutic agents for neurodegenerative diseases. Our mission is to translate genetic and biochemical insights into therapies that promote ...
-
Aura Biosciences Inc. Boston, MA, United StatesAt Aura, our mission is to develop a new class of oncology targeted therapies that deliver meaningful therapeutic benefit to a range of cancer indications with high unmet need in which we believe we can establish a new standard of care. We are focusing the initial development of ...
-
Project Manager, Dept of Surgery
1 week ago
Brigham & Women's Hospital(BWH) Boston, United States**Project Manager, Dept of Surgery** · The Center for Surgery and Public Health (CSPH) has been at the forefront of public health research of surgical care delivery within and throughout our nation's healthcare system. Utilizing innovative research methodologies grounded in clini ...
-
Community Care Cooperative Boston, United States**Title**:Programmer Analyst, Fenway Institute Applications · **Reports to**: Director, Fenway Health Data Analytics · **Classification**: Individual Contributor · **Location**:Hybrid · **Job description revision number and date**: V.20; · **Organization Summary**: · Community C ...
Senior Director/Executive Director, Preclinical Research and Development - Boston, MA, United States - Aura Biosciences Inc.
Description
About Aura:
At Aura, our mission is to develop a new class of oncology targeted therapies that deliver meaningful therapeutic benefit to a range of cancer indications with high unmet need in which we believe we can establish a new standard of care. We are driven by our passion and commitment to science and the patients battling cancer who are relying on us to pioneer these new therapies.
We are focusing the initial development of our VDC technology platform to treat tumors of high unmet need in ocular and urologic oncology. AU-011, our first VDC candidate, is being developed for the first line treatment of primary choroidal melanoma, a rare disease with no drugs approved. Beyond primary choroidal melanoma, we are developing AU-011 in additional ocular oncology indications, including choroidal metastases. Leveraging our VDCs' broad tumor targeting capabilities, we also plan to initiate a clinical program in non-muscle invasive bladder cancer, or NMIBC, our first non-ophthalmic solid tumor indication.
Role & Responsibilities:
The Sr./Exec. Director will perform various duties in support of preclinical development including helping to set the strategic direction for several preclinical programs tracking towards INDs, providing scientific input regarding needed preclinical studies, generating and executing on a plan to deliver preclinical data that supports INDs and First in Human Trials, representing the company in research meetings and developing and maintaining key scientific relationships in the field, including preclinical CROs and academic laboratories.
Essential functions:
In partnership with senior management, provide the overall strategic preclinical direction and scientific leadership for several preclinical development-programs.
Responsible for all areas of preclinical research and development, including generating pharmacology and toxicology data, preclinical trial strategy and design, preparation of the preclinical development plan to support successful INDs, and contribution to regulatory strategy.
Lead the evaluation and selection of preclinical vendors and consultants that are best positioned to support Aura R&D goals.
Demonstrated ability to design preclinical studies and, with outsourcing partners, drive on time execution within planned budgets.
Lead scientific affairs activities, including preclinical information and establishing relationships with key KOLs.
Obtain key stakeholder review and endorsement of science and preclinical aspects of all development programs.
Stay current with GLP and regulatory requirements to support preclinical submission regulatory submissions including INDs.
Interface with clinical development leadership to ensure preclinical activities are aligned with long term project goals.
Develop clear preclinical trial strategies, design and write non-GLP and GLP study protocols, monitor, document, and interpret clinical study data.
Responsible for preparation of preclinical sections of regulatory documents (INDs, IBs, etc.) and study reports; contribute to the preparation and conduct of meetings with FDA/EMA.
Interface with Business Development and Finance to provide subject matter expertise on all preclinical strategic initiatives, including competitive and complementary products, technologies and companies.
Qualifications:
Ph.D. in scientific discipline with preclinical experience in ophthalmology and/or oncology preferable.
10 years or more of full time industry experience in preclinical development preferred with a minimum experience of 5 years required; direct experience managing, planning organizing, implementing, and completing phase I-III clinical trials.
This person will 'own' preclinical development and have a 'role up your sleeves and get it done' approach that is critical in biotech.
Direct experience in toxicology and clinical pharmacology preferred.
#J-18808-Ljbffr