- Lead and manage the In Vivo Pharmacology team in performing critical preclinical efficacy studies across different clinical indications.
- Design, execution, and analysis of pharmacology studies to support the advancement of candidates along the developmental pipeline.
- Identify, initiate, and manage collaborations with CROs and academic labs as appropriate to driving projects forward.
- Provide strategic input to project teams.
- Integrate data to provide a detailed understanding of the pharmacology of therapeutic proteins to enable understanding of in vitro MOAs and in vivo correlates of efficacy.
- Establish biomarker strategies to support translational studies.
- Implement procedures for data capture and management.
- Support preparation of regulatory documents as needed.
- Maintain scientific and technical expertise through familiarity with scientific literature.
- Contribute to building a positive, team-oriented biotech culture.
- PhD in pharmacology or biological disciplines such as immunology, cellular biology, or oncology, with 8+ years direct pharmaceutical experience beyond postdoctoral work.
- In depth in vivo pharmacology experience, particularly on the design and execution of rodent disease models across broad clinical indications. Experience in hematology and autoimmune models is a plus.
- Demonstrated leadership of teams of in vivo scientists to drive go/no go decisions.
- Extensive experience in managing the design and execution of studies at CROs.
- History of translational sciences support for preclinical small molecule programs.
- Ability to manage priorities and drive multiple projects.
- Direct experience in supporting IND strategy and documentation, including writing relevant pharmacology sections of INDs.
- Excellent oral and written communication skills across all levels.
- Prior experience working in smaller companies is highly preferred.
- Passion to develop drug candidates to make an impact in patients' lives.
- Willingness to go beyond expectations to achieve critical objectives.
- Recognition of critical path activities required to succeed in drug discovery
- Push Boundaries: We create a legacy with breakthrough science in service of patients.
- Inject Energy: We build strengths from different perspectives and tell it like it is
- Own it: We transcend our job descriptions and relentlessly follow through on our commitments.
- Go all out: We work quickly and with conviction.
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Director, In Vivo Pharmacology - Somerville, United States - Cellarity
Description
What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way.
What this position is all about:
Cellarity is seeking an energetic, talented and highly motivated Director/Assoc Director to lead our In Vivo Pharmacology department and play a vital role in the company's efforts to progress small molecule lead candidates to IND. The candidate will be responsible for internal and external in vivo studies in rodent (and non-rodent) species. The successful candidate will represent in vivo pharmacology in program teams to rapidly advance Cellarity's drug discovery programs. S/he will be comfortable working in and contributing to a highly dynamic and cross-functional team environment. The ideal candidate must be independent, driven, open-minded, curious, goal-oriented, have excellent communication skills and work in a fast-paced entrepreneurial environment.
What you would be responsible for:
What experiences will you need:
What sets you apart:
What it's like to work at Cellarity:
At Cellarity, we
