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    Research Fellow - Boston, United States - Mass General Physicians Organization(MGPO)

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    Description
    The Center for Precision Imaging (Director: Umar Mahmood, MD, PhD) at the Massachusetts General

    Hospital Martinos Center/Harvard Medical School has openings for highly qualified individuals at the

    post-doctoral level with strong background in preclinical PET molecular imaging and interest in

    molecular imaging of cancer. Our Center is at the forefront of personalized PET molecular imaging and

    we are working to pioneer novel precision imaging and therapy approaches. We have a long-standing

    interest in developing and translating targeted biological PET probes for improved tumor characterization

    for personalizing cancer treatment and autoimmune conditions. Over the past decade, we have

    produced many PET and optical imaging probes for assessing immune system activation, receptor

    imaging, imaging of the tumor microenvironment and interrogation of metabolome. Our group has led

    ome of the first efforts to diagnose therapeutic resistance through receptor imaging and feedback loop

    ignaling, monitor and predict the immune response in cancer immunotherapy and utilize targeted

    imaging to determine effective therapy dosing, among others. These efforts have led to two first-inhuman

    imaging agents, most recently 68Ga-NOTA-hGZP for imaging granzyme B, currently in open trial

    for clinical validation.

    Selected candidate(s) will be involved in a wide range of preclinical imaging projects using our

    proprietary PET probes for imaging and therapeutic radiopharmaceuticals for treatment of cancer.

    Candidates should have a PhD degree and ideally previous experience in PET image acquisition, image

    analysis, radiolabeling with radiometals, working with small animal models and basic wet lab skills.

    Proficiency in scientific writing is strongly desired. Interested candidates should email a cover letter, CV

    (including a full list of publications), a statement of research interests and goals and the contact

    information for 3 referees. Please send to

    Qualifications

    Requirement

    PhD in chemistry, biochemistry, biomedical engineering, molecular biology or related field

    Interest in cancer molecular imaging and radiotheranostic

    Previous experience with preclinical PET imaging and/or radio-labeling with radiometal

    Experience with PET image analysi

    Previous experience with routine laboratory techniques such as cell culturing, Western blot, IHC, and

    flowcytometry is preferred.

    A track record of productive research and publication

    Excellent verbal and written communication skill

    EEO Statement

    Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.

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