- Obtains training and certification in human subjects' research.
- Optimizing the strategy and protocol for blood sample collection in TruCulture Tubes followed by LPS stimulation and tranfer to Smart Tube, Red Top Tube, Whole Blood, BD to separate PBMCs and organize the shipping from clinical site to research laboratory/SDI for stage I. Ensures appropriate set up and processing of sample collection and measurement systems.
- Establish procedure optimization, CyTOF panel design and data analysis consultation, consult with users regarding potential mass cytometry projects including. Standardize and optimize Nuclei Isolation Single-Cell Multi-Omic ATAC- & RNA-seq for stage II
- Coordinates, supervises, and assists in data collection of study subject with clinical site team along with project manager and Cytokine Reference Lab (CRL).
- Perform masscytometry (CyTOF) analysis to execute comprehensive phenotyping of the immune subsets, functional assays for T and B cells at the bench and contribute to research and development of assays with supervision.
- Understanding of sample preparation, instrument optimization and data analysis.
- Build and optimize mass cytometry antibody panels, conjugation and QC of mass cytometry reagents.
- Thawing, washing, purification, culture of T cells, B cells and other cell types using sterile technique.
- Prepare media, and solutions under sterile conditions ahead of time for thawing and culturing cells and performing immunological assays, CyTOF staining and sample acquisition.
- Maintain records of procedures and resultant data manually and electronically.
- Perform basic data quality evaluation, cleaning and normalization of FCS files and help in analyze data using licensed software.
- Computer knowledge to enter data from experiments into existing databases; spreadsheets and web-based applications.
- Conduct background literature search on relevant topics including current
- Establish and maintain a working knowledge of the principles behind daily work.
- Participates in the
- Assists PI in training and mentoring research staff and undergraduate and
- Establishes new research protocols and procedures.
- Assist with development of protocol for process improvement projects.
- Processing of blood and tissue samples from Human and Nonhuman primates.
- Restocking, ordering and keeping inventory of reagents, solutions and
- Culturing cells and changing media with sterile technique, long term sterile
- Participate in lab meetings with collegiate and positive input for the team's work.
- Assist researchers with performing other immunological studies.
- MD or Ph.
- Applies knowledge and skills to a recurring task or activity with emphasis typically on precision and timeliness of execution. Experience working with human and nonhuman, mice samples. Knowledge of aseptic technique and a familiarity with cell culture techniques.
- Proficiency with Microsoft Office programs.
- Flow and Masscytometry
- Cell culture, molecular biology
- Competitive wages, paid holidays, and generous time off
- Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
- Low-cost medical, dental, and pharmacy plans
- Healthcare and dependent care flexible spending accounts
- University HSA contributions
- Disability and employer-paid life insurance
- Employee wellbeing program
- Excellent retirement plans with employer contribution
- Public Service Loan Forgiveness (PSLF) opportunity
- Financial counseling services
- Employee Assistance Program with eight sessions of counseling at no cost
-
post-doctoral associate
2 weeks ago
University of Minnesota Minneapolis, MN, United StatesAbout the Job · The School of Public Health (SPH) is committed to antiracism and anti-oppression and welcomes you to join us in our pursuit of building equity and driving justice. We particularly encourage applications from those who belong to groups that have been historically u ...
-
Post-Doctoral Associate
2 weeks ago
University of Minnesota, Twin Cities Minneapolis, United StatesThe ENACT Research Group is seeking a Postdoctoral Associate to assist with studies that investigate the role of nutrition in cancer prevention and survivorship using technology. We have several ongoing projects that are available for the successful Doctor, Associate, Research, E ...
-
Post-Doctoral Associate
2 weeks ago
University of Minnesota Minneapolis, United StatesAbout the Job · Applications are invited for a full-time postdoctoral associate position in Biostatistics in the School of Public Health, University of Minnesota, Minneapolis, MN. For more information about the Biostatistics Division, visit · The School of Public Health is commi ...
-
Post-Doctoral Associate
5 days ago
University of Minnesota Minneapolis, United StatesAbout the Job · The Translational NeuroEngineering Laboratory (TNEL) in the University of Minnesota Department of Psychiatry has a multi-year funded opening for a post-doctoral Researcher in the area of biomarkers discovery for psychiatric illness. Our laboratory develops technol ...
-
Post-Doctoral Associate
2 weeks ago
University of Minnesota Minneapolis, United StatesAbout the Job · All required qualifications must be documented on application materials. · Required Qualifications: · * Candidates must have received their PhD degrees in cell biology or related field and should have experience in cancer biology. · * Experience in cell culture an ...
-
Post-Doctoral Associate
2 weeks ago
University of Minnesota Minneapolis, United StatesAbout the Job · About the Job: · Professor Mihai Marasteanu is seeking a post-doctoral associate who will take the lead on a variety of research projects and tasks. This person will interact with, lead, and assist graduate and undergraduate students in the research group. · 90% R ...
-
Post-Doctoral Associate
5 days ago
University of Minnesota Minneapolis, United StatesAbout the Job · POSITION ANNOUNCEMENT · Postdoctoral Associate (9546) · Department of Entomology · College of Food, Agricultural and Natural Resource Sciences (CFANS) · University of Minnesota St Paul, MN · Recruiting for a Postdoctoral Associate position (jobcode 9546) researchi ...
-
Post-Doctoral Associate
3 weeks ago
University of Minnesota Minneapolis, United States Regular, Full or Part timeJob ID356500 · LocationTwin Cities · Job FamilyAcademic · Full/Part TimeFull-Time · Regular/TemporaryRegular · Job Code9546 · Employee ClassAcad Prof and Admin · About the Job · The Department of Earth & Environmental Sciences may have positions available (contingent upon funding ...
-
post-doctoral associate
2 weeks ago
University of Minnesota Minneapolis, MN, United StatesAbout the Job · Essential and Other Functions: · 80% Laboratory-based studies · Design, conduct, analyze experiments and report findings to PI or research team. · 10% Writing · Lead manuscript writing and contribute to grants and reviews. · 10% Mentoring · Mentor undergraduate st ...
-
Post-Doctoral Associate
5 days ago
University of Minnesota Minneapolis, United States Regular, Full or Part timeJob ID348185 · LocationTwin Cities · Job FamilyAcademic · Full/Part TimeFull-Time · Regular/TemporaryRegular · Job Code9546 · Employee ClassAcad Prof and Admin · About the Job · Post-Doctoral Associate · Job Code: 9546 · Percent Time: 100% · Anticipated Initial Appointment Period ...
-
Post-Doctoral Associate
2 weeks ago
University of Minnesota Minneapolis, United StatesAbout the Job · Job Duties/Responsibilities: · 1. Participate in the design and evaluation of research studies in development of cancer therapeutics based on viral vectors. The activities include cloning, cell culture, virus amplification/purification, viral vector design and con ...
-
Post-Doctoral Associate
2 weeks ago
University of Minnesota Minneapolis, United StatesAbout the Job · Overview · Department of Surgery (DOS, ) at the University of Minnesota is seeking two postdoctoral research associates to join a team working on · multiple research projects in the field of health data science, artificial intelligence and natural language process ...
-
Post-Doctoral Associate
5 days ago
University of Minnesota Minneapolis, United StatesAbout the Job · Postdoctoral Position · An immediate position is available in Dr. Guedes Laboratory at the University of Minnesota Twin Cities campus. We are an interdisciplinary team working on developing strategies to mitigate opioid use and the impact of opioid overdose. The s ...
-
Post-Doctoral Associate
5 days ago
University of Minnesota Minneapolis, United StatesAbout the Job · The Translational NeuroEngineering Laboratory (TNEL) in the University of Minnesota Department of Psychiatry has a multi-year Federally funded opening for a postdoctoral scholar working at the intersection of neuroscience, electrophysiology, human behavior, and cl ...
-
Post-Doctoral Associate
2 weeks ago
University of Minnesota Minneapolis, United StatesAbout the Job · The Department of Neurosurgery at the University of Minnesota invites applications for postdoctoral research associate position from candidates with a Ph.D., degree, and with a record of outstanding training in gene therapy and regenerative medicine in neuroscienc ...
-
Post-Doctoral Associate
5 days ago
University of Minnesota Minneapolis, United StatesAbout the Job · Postdoc in Phytochemical Insect Pest Management · Qualifications: · Minimum · * Ph.D. in plant science or related discipline at time of appointment. · * Experience conducting laboratory assays of insect feeding/oviposition deterrents on · plant materials. · * Expe ...
-
post-doctoral associate
2 weeks ago
University of Minnesota Minneapolis, MN, United StatesAbout the Job · Job description · The Postdoctoral Associate position is available immediately. The scientist will work closely with UMN and external scientists with expertise in microfluidics, nanotechnology, prion biology, epidemiology, and diagnostics. The successful candidate ...
-
Post-Doctoral Associate
5 days ago
University of Minnesota Minneapolis, United StatesAbout the Job · We are seeking a postdoc for our interdisciplinary research project studying aging, balance control, and brain neural and vascular health that is sponsored by the National Institutes of Health. This project aims to understand the links between vascular brain funct ...
-
Post-Doctoral Associate
1 week ago
University of Minnesota Minneapolis, United StatesAbout the Job · The Neuromodulation Research Center (NMRC) at the University of Minnesota is seeking a postdoctoral fellow to study the effects of Parkinson's disease (PD) and deep brain stimulation (DBS) on basal ganglia-cortical brain networks during sleep. Under the direction ...
-
Post-Doctoral Associate
1 week ago
University of Minnesota Minneapolis, United StatesAbout the Job · Title of project: Udall Center - Deep Brain Stimulation in Parkinson's Disease Research Position · The postdoctoral researcher will be involved in the execution of experiments examining the effects of globus pallidus deep brain stimulation on motor and non-motor s ...
Post-Doctoral Associate - Minneapolis, United States - University of Minnesota
Description
About the JobPostdoctoral position in Translational Immunology in Singh Lab at SDI
The Singh laboratory for Comprehensive Immune Studies (CIS) within Schulze Diabetes Institute at Medical School, UMN is looking for full-time postdoctoral fellow in the field of translational Immunology for an NIH funded project focus on understanding functional effects of vagus nerve stimulation (VNS) on immune systems.
We are a laboratory that support and conduct hypothesis-driven research at both the basic and translational levels, with a clear focus on advancing human health.
Our overarching mission is to delve deep into the complexities of the immune system, aiming to pinpoint the central regulators responsible for orchestrating inflammation, Immunity, and tolerance to transplant tissues (islet and kidney).
Using primary human
sample, preclinical model of NHPs, we pave the way for groundbreaking discoveries in immune features that can serve as invaluable biomarkers, ultimately contributing to an enhanced state of human health.
Summary of Position:
The Transplantation Tolerance Laboratories (TTL) within the Schulze Diabetes Institute (SDI) in the Department of Surgery is looking for an outstanding and highly motivated Postdoctoral Associate with a passion for exciting state-of the art technology that explores the world of single cells using mass cytometry.
Overall, the SDI/TTL lab is interested in understanding to what extent VNS alters the immune system and impacts protective immunity.
The candidate will perform deep immune profiling and single-cell ATAC/RNA-seq before and after VNS device implantation to determine whether i) baseline immune signatures predict the response to VNS, ii) clinical improvements correlate with distinct immune system signatures, iii) VNS ameliorates depression and epilepsy by modulating the underlying autoimmunity, iv) changes in immune responses to VNS are stable or fluctuate over time, and v) VNS device parameter settings can bepersonalized based on immune system profiling for enhanced efficacy.
Candidates will have the opportunity to engage in NIH-funded on-going translational and/or observational cohort studies and develop their own project within the ongoing research in a fast-paced behavioral research environment.
This individual will work with a team of translational immunologists and report directly to Amar Singh, Ph.
D, Assistant Professor, within the SDI in the Department of Surgery.
The individual will perform duties and responsibilities as a post-doctoral researcher in the TTL. General laboratory functions are also expected of this position.
About the Study
In this large-scale clinical study, the candidates will work with interdisciplinary team of
PIs and Co-Is join for NIH-funded Research Evaluating Vagal Excitation and Anatomical
Links (REVEAL) project that will take place over three years. REVEAL aims to study the
anatomical connections and functional effects (the cardiovascular, metabolic, autonomic
nervous and immune systems) of vagus nerve stimulation (VNS), which is an FDA-approved treatment for epilepsy and depression.
The position responsibilities include:
Comprehensive immune phenotyping assay to decipher how do VNS modulate the immune response in patients with suspected autoimmune depression and autoimmune epilepsies (75%)
UMN PDA:
post-doc program activities: presentation and preparation of data into figures, written project updates, oral presentations (including lab meetings, post doc seminars, and presentations at local, national, and international meetings); and preparation of manuscripts based on their work.
Required Qualification:
Preferred Qualifications:
Committed to innovation and diversity, the Medical School educates physicians, scientists, and health professionals; generates knowledge and treatments; and cares for patients and communities with compassion and respect.
To learn more about the Department of Surgery, please visit:
Benefits
Working at the University
At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning.
We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.
The University also offers a comprehensive benefits package that includes:How To Apply
Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions.
You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.
Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.
Diversity
The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission.
The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression.
To learn more about diversity at the U:
Employment Requirements
Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.
About the U of M
The University of Minnesota, Twin Cities (UMTC)
The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research.
Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St.
Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.
At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).