- Perform routine analytical testing of RNA-based drug substances, intermediates and formulated drug products using various analytical techniques such as HPLC, LC-MS, UV-Vis, Fluorimetry as well as other specialty instrumentation including but not limited to particle sizers, KF, osmometer, etc.
- Participate in development, optimization and trouble-shooting of the analytical methodologies to characterize RNA-based API and drug product formulations
- In close collaboration with the broad team of RNA, chemistry and formulation scientists, design and perform laboratory research experiments needed to support RNA, chemistry and formulation process development efforts
- Support analytical equipment maintenance, trouble shooting and qualifications
- Support organizing, storage and maintaining inventory of the analytical materials and supplies
- Maintain proper documentation of all experimental procedures and results
- Routine maintenance of equipment.
- Assist in the inventorying and ordering of reagents and other laboratory supplies.
- Perform other duties as needed
- Bachelor's degree in Chemistry, Biochemistry, Molecular Biology, Pharmaceutical, Life Science or equivalent.
- Familiarity with one or more chemical and biochemical techniques such as capillary electrophoresis (Agilent Bioanalyzer 2100, Advanced Analytics Fragment Analyzer), qPCR, HPLC is desired
- Zero to two (0-2) years relevant experience in manufacturing or laboratory research.
- Detail oriented with strong written and verbal communication skills.
- Ability to work independently with minimal supervision, within prescribed guidelines, and as a team member.
- Ability to draft routine reports and keep accurate records of work performed.
- Actively seeks opportunities to increase skills and expertise.
- Able to learn complex task with general instructions and training.
- Able to perform a variety of new techniques.
- Demonstrated ability to follow detailed directions in a research laboratory environment.
- Must be familiar with Microsoft Office applications.
- Catered lunches
- Free variety of snacks and beverages
- Referral Bonuses
- On Campus Gym
- Company sponsored FUN events
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Research Associate I - San Diego, United States - Arcturus Therapeutics Ltd.
Description
Founded in 2013 and based in San Diego, California, Arcturus Therapeutics is an industry leader in the application of RNA technologies for the treatment of disease and improved quality of life.
The company's aim is to develop breakthrough technology and novel therapeutics for rare diseases for which there is no adequate treatment.
Backed by a management team with extensive experience in the discovery and development of RNA medicines, Arcturus is on the forefront of research and development of RNA delivery technologies.
SUMMARY:
The Research Associate, Analytical Development will be responsible for conducting routine analytical characterization of RNA drug substances, intermediates and formulated drug products to support internal process development.
RESPONSIBILITIES:
REQUIREMENTS:
An exciting opportunity to join a company that offers: