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    Research Technician I - Durham, United States - Howard Hughes Medical Institute (HHMI)

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    Full time
    Description

    We currently have an opening for a Research Technician I in the lab of Dr. Cagla Eroglu at Duke University. The Eroglu Lab investigates the cellular and molecular mechanisms that underlie synaptic connectivity in the CNS. Currently, they are continuing to understand the function of astrocyte-neuron communication in the normal mammalian brain. Moreover, they are testing how problems in astrocyte-neuron communication contribute to the pathophysiology of neurodevelopmental disorders and degeneration. More information can be found on their website.

    About the Role:

    We are targeting curious, determined candidates who are passionate about the world of neurobiology, working with others, and have a highly developed desire for continuous learning. We are ideally looking for candidates who are interested in staying in this role for at least two years before moving on to their next opportunity.

    As part of your application, please include information outlining your passion for science, and why you're interested in this role.

    What We Provide:
    • Direct mentorship with 2 senior lab members, getting exposure to cutting-edge science
    • Participation in a lab culture that's built on inclusion, diversity, and dedication to their established values and principles
    What You'll Do:
    • Perform a variety of technical duties to investigate astrocyte morphogenesis and synaptogenesis in the developing and aging mouse and rat brain, including tissue culture, immunocytochemistry, viral-based techniques, microscopy, imaging, image analysis, and PCR.
    • Generation and maintenance of primary rat and mouse neuron and astrocyte cultures, including isolation, plating, feeding, and sterile reagent preparation.
    • Support the maintenance of mouse and rat colonies including setting up breeding, weaning and genotyping.
    • The candidate will be expected to document procedures and collect data in an organized and complete fashion following the laboratory SOP.
    • Tissue processing for histology, and quantitation of various markers.
    • Collect, record, organize and verify the accuracy of data; perform calculations and prepare charts, graphs, and reports.
    • Participate in laboratory meetings and planning sessions. Review literature as needed to build essential knowledge of the lab's scientific area of focus.
    • Laboratory maintenance duties such as assisting with maintaining reagent and equipment inventories.
    What You Bring:
    • A bachelor's degree in biology, neurobiology, or related fields; or equivalent combination of education and experience
    • A passion for science, and for the work of the lab
    • Comfort with working with animal models
    • Excellent verbal and written communication skills.
    • Excellent organizational skills, time management skills, and attention to detail. Ability to use good judgment in managing deadlines and responding to inquiries.
    • Strong enthusiasm to learn new techniques and expand your scientific knowledge.
    • Experience with live mouse handling a strong plus, but not required
    Physical Requirements:

    Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.

    Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

    Please Note:

    This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word "may," the Essential Duties and Responsibilities described above are "essential functions" of the job, as defined by the Americans with Disabilities Act.



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