- The individual will work in the laboratory and be responsible for the experimental execution and data analysis for research studies supporting cutting edge therapeutic programs and platform discovery research.
- Employ CRISPR editing technology for the genetic modification of human B cells.
- Develop and conduct in vitro analytical and functional bioassays for characterizing engineered B cells.
- Assist in the expansion and cell banking of engineered cell lines, laboratory maintenance, generation of SOPs and other technical documents as needed.
- Bachelor or Master of Science (MS preferred) in Biology, Immunology, Molecular Biology or Biochemistry, with 5+ years of hands-on experience in the development of new biological therapeutics or pharmaceutical products is required
- Direct experience with flow cytometry, and cell-based assay characterization is a requirement.
- Experience with primary human B cell culture and techniques to transduce and characterize primary B cells is a plus.
- Experience in CRISPR-based engineering of human cells is preferred.
- Detail-oriented, organized, and technically skilled.
- Highly adaptable and responsive, and committed to completing tasks in a timely fashion
- Demonstrated ability to work in a dynamic environment as a team player with a strong work ethic
- Excellent team player with good interpersonal and communication skills
- Able to maintain written records in the form of laboratory notebooks (paper or electronic)
- Excellent oral and written communication skills
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Senior Associate Scientist, Cell Therapy Discovery, B Cell Therapeutics - Waltham, United States - ElevateBio
Description
ElevateBio is a technology-driven cell and gene therapy company, accelerating access to the cutting-edge technologies and expertise to change the future of medicine. Our integrated technologies model offers turnkey scale and biotechnological capabilities to power genetic medicines processes, programs, and companies to their full potential.The Role:
We are seeking a motivated and creative Associate Scientist to join our team to support B cell Therapeutics discovery. Reporting to the Scientist, the Associate Scientist of B-cell therapeutics will be a dedicated and innovative professional. The successful candidate will be a part of the research team focused in developing a research process for novel B cell therapeutics. The ideal candidate would have expertise in lab-based techniques aimed at culturing, editing, and characterizing engineered human primary B cells or transferable skills from working with primary human T cells. This is an exciting chance to join a dynamic organization at the forefront of cell therapies and make significant contributions toward advancing B cell therapeutics as a novel approach to help patients in need.
Here's What You'll Do:
ElevateBio is a technology-driven company built to power transformative genetic medicines today and for many decades to come. The Company commercializes its enabling technologies, manufacturing capabilities, and industry-leading expertise through partnerships to accelerate development across a breadth of therapeutic approaches and modalities. The ElevateBio ecosystem combines multiple R&D technology platforms - including Life Edit, a next-generation, full-spectrum gene editing platform; comprehensive cell engineering technologies; and an expanded viral and non-viral therapeutic delivery platform - with BaseCamp, its end-to-end genetic medicine cGMP manufacturing and process development business, to accelerate the discovery and development of advanced therapeutics.
We aim to be the dominant engine inside the world's greatest scientific advancements harnessing human cells and genes to alter disease.
Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.
Our Vision:
We seek to be the world's most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.
ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
