Scientist II, Downstream Process Development - Plainville, United States - Lifelancer

Lifelancer Plainville, United States

Found in: Talent US C2 - 1 day ago

Full time

Description

What will you do?

Contribute to multiple projects and participate in the planning and execution of process development and scale up activities (both bench and pilot scale).

Serve as functional SME and work collaboratively with other team members on all aspects of downstream execution for viral vector processes.

Participate and/or lead the training and development of other team members.

Prepare and modify documents (development plans, batch records, SOPs, protocols, summary reports).

Identify technical gaps/facility fit challenges for new clients/processes

Support analytical testing for process development and characterization.

Lead Practical Process Improvement (PPI) initiatives

How will you get here?

Education

B.S. in Chemical Engineering, Biochemistry, Biology or related field with 3+ yrs, of experience or Masters degree.

Experience

Design and execution of downstream unit operations
Have understanding of experimental design and be able to independently execute laboratory experiments.
Strong hands-on experience with different purification techniques such as affinity and anion exchange chromatography and associated instrumentation such as AKTA chromatography systems and Unicorn software.
Experience with depth filtration design and sizing including manifold assemblies.
Design and execute DOE studies high-throughput screening for purification process improvements including parameter optimization, scale-up, and buffer selection.
Viral reduction filtration and support for viral clearance studies.
Has completed tangential flow filtration along with final formulation for virus, and plasmid DNA-based gene therapies.
Scale-up of downstream processes, supports process characterization and validation activities.
Effective problem solving and troubleshooting abilities.
Collaborating with Upstream and Analytical Testing/Development teams to build process understanding and design and execution of in-process testing and control assays

Knowledge, Skills, Abilities

Working level knowledge of downstream purification of mammalian and insect cell culture processes
Experience in scale up and scale down of purification processes.
Ability to analyze and summarize scientific data
Understanding of cGMP and regulatory requirements of biopharmaceutical manufacturing.
Strong interpersonal and communications skills; written and oral
Ability to function in a rapidly changing environment handle multiple priorities.
A flexible work schedule is required including Weekend and night as needed to support lab activities.

Please use the below link for job application and quicker response

Manager - Downstream Process Development

Found in: ZipRecruiter Test10S US C2 - 1 day ago

Lifelancer Plainville, United States

Job Description · Job DescriptionJob Title: Manager - Downstream Process Development · Location/Division Specific Information: US - Massachusetts Plainville · How will you make an impact? · In Viral Vector Service BioProcess Sciences, we develop, characterize and scale-up bioproc ...
Scientist II, Downstream Process Development

Found in: ZipRecruiter Test10P US C2 - 1 day ago

Lifelancer Plainville, United States

Job Description · Job DescriptionWhat will you do? · Contribute to multiple projects and participate in the planning and execution of process development and scale up activities (both bench and pilot scale). · Serve as functional SME and work collaboratively with other team membe ...
Senior Innovation Expert

Found in: Orion Innovations US - 1 week ago

Crimson Technologies New Britain, CT, United States Freelance

Connecting people and technologies, creating the perfect match for our clients, and always finding the right experts for each challenge - that is our goal at FERCHAU, and we are looking for you: an ambitious Senior Innovation Expert who, like us, wants to take technologies to the ...
Process Development Engineering Manager

Found in: Lensa US 4 C2 - 5 days ago

Amphenol TCS Hamden, United States

Position: · Process Development Engineering Manager · Location: · Hamden, CT · Amphenol Spectra-Strip is enabling the electronics revolution with wire and cable solutions. We are the market leader for products that power the internet, cloud compute and artificial intelligence. ...
Head of Internal Services

Found in: Orion Innovations US - 1 week ago

Titan Industries Bristol, CT, United States Freelance

**Klax International GmbH - Bristol, CT** · **Business Office Berlin** · **Top Management Executive** · **Management** · **Full-time** · - Klax GmbH is the organizational umbrella of the Klax Group. Its main tasks include providing administrative services such as marketing, human ...
Technician II, Process Development

Found in: ZipRecruiter Test10P US C2 - 14 hours ago

Cirtec Medical Corporation Enfield, United States

Job Description · Job DescriptionTHIS POSITION IS ELIGIBLE FOR A $2,250.00 NEW HIRE SIGN-ON BONUS · JOB SUMMARY · The Technician II, Process Development is primarily responsible for providing tools and support to engineering and production while adhering to the quality and cost r ...
Process Development Engineering Manager

Found in: ZipRecruiter Test10S US C2 - 2 days ago

Amphenol TCS Hamden, United States

Job Description · Job DescriptionPosition: Process Development Engineering Manager · Location: Hamden, CT · Amphenol Spectra-Strip is enabling the electronics revolution with wire and cable solutions. We are the market leader for products that power the internet, cloud compute an ...
Employee M/F/D Debt

Found in: Orion Innovations US - 1 week ago

BlueWave Solutions Kensington, CT, United States Freelance

Join the success of a well-established European company in Berlin, Kensington, CT. · Are you interested in working for one of the leading independent fuel management companies in Europe? · As a clerk (m/f) in the payment processing department, you will have the opportunity to act ...
Senior Automation Engineer, Synthetic Process Development

Found in: Lensa US 4 C2 - 6 days ago

The Chemical Engineer New Haven, United States

This is what you will do:Alexions Product Development and Clinical Supply (PDCS) organization is seeking an automation engineer to enable design and deployment of advanced laboratory and process automation systems for the Synthetic Process Development team, with emphasis on ensur ...
Senior Automation Engineer, Synthetic Process Development

Found in: Lensa US 4 C2 - 6 days ago

AstraZeneca New Haven, United States

This is what you will do: · Alexion's Product Development and Clinical Supply (PDCS) organization is seeking an automation engineer to enable design and deployment of advanced laboratory and process automation systems for the Synthetic Process Development team, with emphasis on e ...
Senior Manager, Manufacturing and Process Development Engineering

Found in: Talent US 2A C2 - 3 days ago

TE connectivity Middletown, United States

At TE, you will unleash your potential working with people from diverse backgrounds and industries to create a safer, sustainable and more connected world. Job OverviewTE Connectivity's Manufacturing and Process Development Engineering Teams significantly impact LEANPD-driven ne ...
Quality Supervisor

Found in: SonicJobs Direct Apply US - 4 days ago

Actalent Wolcott, United States Full time

Position Overview: · We are seeking a highly motivated and skilled Quality Supervisor to join our team. As we experience tremendous growth and success, this role will play a crucial part in maintaining our commitment to quality and food safety. · The Quality Supervisor will repo ...
Senior Automation Engineer, Synthetic Process Development

Found in: Lensa US 4 C2 - 6 days ago

The Chemical Engineer New Haven, United States

This is what you will do: · Alexion's Product Development and Clinical Supply (PDCS) organization is seeking an automation engineer to enable design and deployment of advanced laboratory and process automation systems for the Synthetic Process Development team, with emphasis on e ...
VP, Financial Consultant

Found in: SonicJobs Direct Apply US - 6 days ago

Charles Schwab Hartford, United States Full time

Position Type: RegularYour opportunity · At Schwab, you're empowered to make an impact on your career. Here, innovative thought meets creative problem solving, helping us "challenge the status quo" and transform the finance industry together. · Schwab's branch team is at the hear ...
Inbound Supervisor

Found in: SonicJobs Direct Apply US - 6 days ago

SYSCO Hartford, United States Full time

Company: · US1225 FreshPoint Connecticut, LLCZip Code: · 06114Minimum Level of Education: · High School or EquivalentMinimum Years of Experience: · 1 YearEmployment Type: · Full TimeTravel Percentage: · 0Compensation Range: · $61, $92,500.00The compensation range provided is in ...
Dispatcher (male/female/diverse)

Found in: Orion Innovations US - 1 week ago

Nexus Innovations Collinsville, CT, United States Freelance

**Responsibilities**: · - As a dispatcher (m/f/d) you will be responsible for scheduling the instructors and seminar assistants. · - You coordinate the processes and procedures for cancellations and last-minute changes, ensuring an optimal learning experience for our participants ...
Trach/Vent Nurse

Found in: SonicJobs Direct Apply US - 2 days ago

Aveanna Healthcare Middletown, United States

Registered Nurse (RN) is responsible for providing and documenting skilled nursing care in accordance with the developed care plan and physicians orders for each individual patient while adhering to confidentiality standards and professional boundaries at all times. · Essential J ...
General Manager

Found in: SonicJobs Direct Apply US - 3 days ago

Chipotle Middletown, United States Full time

· General Manager · DescriptionCULTIVATING A BETTER WORLD · Food served fast doesn't have to be a typical fast food experience. Chipotle has always done things differently, both in and out of our restaurants. We're changing the face of fast food, starting conversations, and dir ...
Senior Civil Engineer

Found in: Zoho Direct Apply - 4 days ago

Omm IT Solutions Hartford, United States

The candidate should be able to work in a fast paced and ever-changing environment where no two days are ever the same. · The ideal candidate needs to have a firm grasp of the residential and commercial civil site design process, as well as, a basic idea of the municipal land-us ...
Apprentice General Manager

Found in: SonicJobs Direct Apply US - 4 days ago

Chipotle East Longmeadow, United States Full time

· Apprentice General Manager · DescriptionCULTIVATING A BETTER WORLD · Food served fast doesn't have to be a typical fast food experience. Chipotle has always done things differently, both in and out of our restaurants. We're changing the face of fast food, starting conversatio ...