- Develop, validate and implement innovative genetic and genomic biomarker assays for clinical studies
- Generate and interpret data to enable proof of mechanism, dose selection & proof of biology across early clinical programs and present results at internal meetings
- Partner with outsourcing functions to evaluate new CROs, drive transitioning and monitoring of internally developed assays to external vendors
- Conduct activities according to the appropriate SOPs and guidelines in compliance with Novartis quality expectations and Values and Behaviors
- Develop knowledge in additional biomarker modalities and/or technologies
- Network internally and externally to expand scientific and technical knowledge
- Develop and validate fit-for-purpose biomarker solutions
- Independently design, execute, and interpret experiments
- Ensure high quality and timely delivery of internal and external results
- Providing subject matter expertise for transferring, implementation and monitoring of assay development, validation and sample analysis at external provider
- Novartis: e-mail [email protected] or call
- Sandoz: e-mail [email protected] or call:
- BS/MS degree in Biology, Immunology, Cell biology, or equivalent and 5+ years of relevant professional experience
- Experience in PCR based assays development (e.g. qPCR, ddPCR) and related software analysis
- Experience in profiling genomic technologies, such as RNAseq, scRNAseq and DNAseq
- Ability to communicate effectively with excellent presentations skills.
- NGS data analysis skills
- Professional experience in the pharmaceutical or biotechnology environment, particularly in clinical biomarker development and bioanalytical assays for genetic and genomic biomarkers
- Competent in nucleic acid extractions from human clinical samples (whole blood, tissues & other body fluids)
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Senior Scientist, Clinical Genetics and Genomics - Cambridge, United States - Novartis AG
Description
About the RoleThis role is located in Cambridge, MA and will not have the ability to be located remotely.
About the role:
In this laboratory-based scientist role in BMD, you will apply your hand-on expertise to implement genetics and genomic assays including targeted and NGS-based technologies.
Your Key Responsibilities:
Our Expectations:
We are Equal Opportunity Employers and take pride in maintaining a diverse environment.
We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Accessibility and Reasonable Accommodations:
Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:
Essential Requirements:
Desirable Requirements:
Why Novartis:
Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world.
How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions.Be a part of this mission and join us Learn more here:
You'll receive:
You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook.
Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
Accessibility and Reasonable Accommodations:
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call and let us know the nature of your request and your contact information.
Please include the job requisition number in your message.Novartis Compensation and Benefit Summary:
The pay range for this position at commencement of employment is expected to be between $92,800 - $139,200/year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period.
Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities.
The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered.
Details of participation in these benefit plans will be provided if an employee receives an offer of employment.If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here:
Why Novartis:
Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?
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