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    Research Scientist - Boston, United States - Massachusetts General Hospital

    Massachusetts General Hospital
    Massachusetts General Hospital Boston, United States

    3 weeks ago

    Default job background
    Full time
    Description
    Research Scientist Description

    GENERAL SUMMARY/OVERVIEW:

    A Research Scientist position is available in the laboratory of Marc Wein at the Massachusetts General Hospital (MGH) Endocrine Unit. This position offers an opportunity to apply skills in mouse genetics, bone cell biology, molecular/cellular biology, and advanced histopathology analysis of dental issues. Background in one or more of these areas is preferred. This is a full time 40-hour/week position

    The Wein laboratory investigates molecular mechanisms used by parathyroid hormone to exert its function in target cells in bone and other tissues. We employ wide-ranging techniques to study parathyroid hormone signaling in vitro and in vivo. These studies will lead to an improved understanding of skeletal responses to PTH, and have important implications for the treatment of osteoporosis, dental disease, and chronic kidney disease.

    Responsibilities comprise, but are not limited to:

  • Animal husbandry to track the status of a complex colony of genetically-modified mice
  • Mouse necropsy and collection of dental-relevant tissues for histopathology and primary cell culture
  • Histopathology analysis of jaw and dental tissues
  • Immunohistochemistry and in situ hybridization of jaw and dental tissues
  • RNA isolation, RT-qPCR
  • Protein isolation, immunoblotting
  • Keeping an active and accurate laboratory notebook
  • Regular meetings with members of research team to present and discuss data
  • Manuscript writing, figure preparation
  • Present data at local and international scientific meetings
    • Qualifications

    EDUCATION/EXPERIENCE:

  • Master's Required. PhD, MD, DDS, DMSc, or MD/PhD in biomedical sciences preferred.
  • Minimum of 3 years of research experience (inclusive of graduate studies) required.

    • SKILLS/ ABILITIES/ COMPETENCIES REQUIRED:

  • Demonstrated ability to work independently as well as in a group environment.
  • Strong research design and analytical skills, with demonstrated ability to problem solving.
  • Strong organizational and communication skills.
  • Demonstrated analytical skills to problem solve effectively.
  • Experience in cell culture, molecular/cell biology, biochemistry, and mouse models of skeletal and mineral metabolism disease.

    • WORKING CONDITIONS:

  • Duties will be performed in a research laboratory.
  • No direct patient contact will occur.
  • Must be willing to work with mice.
  • Flexible work hours conducted over a forty-hour work week.
    • EEO StatementMassachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.

    Primary Location

    :MA-Boston-MGH Main Campus

    Work Locations

    :MGH Main Campus55 Fruit StreetBoston02114

    Job

    :Technician/Technologist/Scientist

    Organization

    :Massachusetts General Hospital(MGH)

    Schedule

    :Full-timeStandard Hours:40

    Shift

    :Day JobPosted Shift Description:M-F 8:30AM-5:00PM

    Employee Status

    :RegularRecruiting Department:MGH Endocrine

    Job Posting

    :May 22, 2024
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