Postdoctoral Fellow-MSH - New York, United States - Mount Sinai Hospital

Description

Job Description

The Gregorio Lab in the Cardiovascular Research Institute (CVRI) at the Icahn School of Medicine at Mount Sinai is seeking highly motivated candidates for the full-time position of Postdoctoral Research Associate I. Dr. Gregorio's NIH-funded research incorporates molecular, cellular and physiological approaches on the RNA/protein level to identify molecular mechanisms that underlie contractile protein function in heart and skeletal muscle diseases. Current studies focus on the role of RNA-binding proteins in muscle function that are altered during normal development and in disease such as Duchenne Muscular Dystrophy. The laboratory generates, analyzes, and integrates high-throughput fluorescence imaging, molecular biology and biochemistry to determine the mechanism of RNA binding proteins in cells (e.g., iPSCs, primary myocytes) and animal models that reflect patho/physiological states. The successful Postdoctoral candidate will possess a cell/molecular skill set with an emphasis on RNA biology appropriate to accomplish the lab's goals. In addition, they will possess the drive required to research complex disease and will be able to work independently as well as collaboratively. CVRI is dedicated to training the next generation of scientists, and the Postdoctoral candidate will benefit from the diverse and interdisciplinary environment.

Responsibilities

Roles & Responsibilities:

• Lead a research project in close collaboration with the PI and other lab members.
• Innovate new areas of experimental inquiry.
• Advance technical aspects of experimental approaches and mechanistic understanding of biological problem.
• Mentor junior lab members and contribute to a productive scientific environment.
• Maintain detailed records and disseminate research findings in meetings and as manuscripts in scientific journals: strong writing skills are essential
• Apply for independent funding and contribute to grant proposals submitted by the PI.
• There may be additional duties assigned as it relates to this position.

Qualifications

Requirements:

Minimum Requirements:

• MD or PhD in biochemistry, molecular or cellular biology, physiology, biotechnology, biomedical engineering, or related field by time of hire.
• Documented ability to conduct original research.
• Ability to write manuscripts and grants proposals.
• Ability to work with small animals.

Preferred Qualifications:
*Experience with recombinant proteins, muscle proteins, and handling/dissection of small rodents. *Experience with enzyme kinetics/biochemical assays of protein-protein interactions. *Experience with fluorescence microscopy. *Experience with Duchenne Muscular Dystrophy Models. *Expertise in cardiac and skeletal muscle biology, post-transcriptional and translational regulation in heart and skeletal muscle disease pathology. *Experience in computational biology.

Non-Bargaining Unit, J16 - Cardiovascular Research Institute - ISM, Icahn School of Medicine

Strength Through Diversity

The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinais unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by:

• Using a lens of equity in all aspects of patient care delivery, education, and research to promote policies and practices to allow opportunities for all to thrive and reach their potential
• Serving as a role model confronting racist, sexist, or other inappropriate actions by speaking up, challenging exclusionary organizational practices, and standing side-by-side in support of colleagues who experience discrimination
• Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers

We work hard to acquire and retain the best people and to create an inclusive, welcoming and nurturing work environment where all feel they are valued, belong, and are able to professionally advance. We share the belief that all employees, regardless of job title or expertise, contribute to the patient experience and quality of patient care.

Explore more about this opportunity and how you can help us write a new chapter in our history

Who We Are

Over 42,000 employees strong, the mission of the Mount Sinai Health System is to provide compassionate patient care with seamless coordination and to advance medicine through unrivaled education, research, and outreach in the many diverse communities we serve.

Formed in September 2013, The Mount Sinai Health System combines the excellence of the Icahn School of Medicine at Mount Sinai with seven premier hospitals, including Mount Sinai Beth Israel, Mount Sinai Brooklyn, The Mount Sinai Hospital, Mount Sinai Queens, Mount Sinai West (formerly Mount Sinai Roosevelt), Mount Sinai St. Lukes, and New York Eye and Ear Infirmary of Mount Sinai.

The Mount Sinai Health System (MSHS) provides equal employment opportunity to all its employees and applicants for employment without unlawful discrimination on the basis of their actual or perceived race, creed, color, religion, national origin, sex, gender, gender expression, gender identity, age, disability, marital or parental status, sexual orientation, veteran, immigration, citizenship, or other protected status.

EOE including Veterans and Disabled

About Us

Strength Through Diversity

The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinai's unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by:

• Using a lens of equity in all aspects of patient care delivery, education, and research to promote policies and practices to allow opportunities for all to thrive and reach their potential.
• Serving as a role model confronting racist, sexist, or other inappropriate actions by speaking up, challenging exclusionary organizational practices, and standing side-by-side in support of colleagues who experience discrimination.
• Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers.

We work hard to acquire and retain the best people and to create an inclusive, welcoming and nurturing work environment where all feel they are valued, belong and are able to professional advance. We share the belief that all employees, regardless of job title or expertise contribute to the patient experience and quality of patient care.

Explore more about this opportunity and how you can help us write a new chapter in our history

"About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes approximately 7,400 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 14 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism."

EOE Minorities/Women/Disabled/Veterans