Jobs
>
Seattle

    Process Engineer - Seattle, United States - Alpine Immune Sciences, Inc.

    Alpine Immune Sciences, Inc.
    Alpine Immune Sciences, Inc. Seattle, United States

    3 weeks ago

    Default job background
    Description


    Alpine Immune Sciences is a leading clinical-stage biopharmaceutical company dedicated to discovering and developing innovative, protein-based immunotherapies for autoimmune and inflammatory diseases.

    Exciting challenges lie ahead-guided by our core values, we'll meet these challenges. Join us

    Alpine Immune Sciences is seeking a highly motivated individual to join the CMC team as a Process Engineer (Upstream).

    This individual will be part of a team working to develop upstream processes that are robust, scalable, well characterized, and economical for clinical and commercial manufacturing.

    The successful candidate should have experience in cell culture, cell culture and perfusion manufacturing unit operations and be able to interact with Alpine's network of external CDMOs.

    This is a Hybrid role that will be based out of our Seattle, WA office.

    Duties and responsibilities:


    • Apply a fundamental understand of mammalian cell culture operations including single-use bioreactors and perfusion and harvest technologies to support technology transfer and scale-up of clinical/commercial manufacturing processes.
    • Apply a good understanding of engineering principles for the scaling of cell culture unit operations from bench to manufacturing scale.
    • Provide floor support/person-in-plant for manufacturing activities during clinical and validation campaigns (travel may be required)
    • Work with external vendors (CDMO) and provide leadership/guidance in solving clinical and commercial drug substance process issues involving equipment, scale and raw materials.
    • Experience with statistical Design of Experiments and/or Quality by Design.
    • Experience with risk assessments (FMEA)
    • Develop process knowledge and ownership.
    • Authors technical documents, including technical reports and protocols.
    • Participate in cross functional teams and represent Upstream CMC.
    Qualifications:


    • B.S (M.S./ Ph.
    D. a plus) degree in an Engineering or Scientific field with 4 years or more industry experience in cell culture process development, characterization and/or commercial process support.


    • Experience with scaling up unit operations with an understanding of cGMP requirements, FDA, and ICH guidelines.
    • Experience in communicating and presenting complex technical information to internal and external teams.
    • Self-motivated, ability to muti-task, and a desire to acquire new technical skills.
    • Flexibility to change project objectives and enthusiasm.
    • Excellent written and verbal communication skills.
    • Works well independently and in teams in a highly dynamic, cross-disciplinary environment.
    #LI-hybrid

    At Alpine we engage equitable workplace strategies to ensure fair compensation. Actual compensation is dependent upon current market data, experience, and pay parity within our organization. This position is a Professional level position, with a compensation range of $100,000 - $115,000. Note that candidates must be located in WA state.

    We take care of our employees with a competitive benefits package that includes stock options, annual bonus, premium medical, dental, and vision coverage for employees and their dependents, as well as life and disability benefits, FSA, and 401(k) plans.

    We believe quality time outside the office is vital to our employees' satisfaction at work, so our flexible PTO plan of 160 hours, generous holiday time (generally 12 days), and parental benefits encourages team members to take time off so they can come back refreshed.

    Alpine team members enjoy competitive salaries and equity participation (stock options).


    Alpinists share a passion for meaningful work and are committed to solving the most complex problems in immunology to create new therapies for patients.

    We believe in innovative thinking, collaboration, flexibility, bias for action, and healthy debate.

    To foster our team of outstanding scientists and business professionals, we provide a premier work environment with a state-of-the-art lab and office spaces with truly inspiring views, and an open design to facilitate teamwork.

    Our treasured culture has been shaped by our diverse team who truly enjoys working and playing together.

    We nurture Alpine's culture in many ways, including all-company social events and happy hours, lunch-and-learn and education opportunities, interest groups like book club and movie nights, peer-to-peer recognition programs, a robust wellness program to help support physical, mental, and emotional health, and more.

    Alpine is committed to creating a diverse environment and is proud to be an equal opportunity employer.

    All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

    Alpine is also committed to compliance with all fair employment practices regarding citizenship and immigration status.

    Our office and lab are located in the blossoming biotech neighborhood of Eastlake in Seattle.

    Alpinists enjoy the flexibility to work onsite, remotely, or a hybrid schedule, with evolving options as we prioritize keeping Alpinists safe and healthy.

    Onsite employees enjoy an open-office layout with comfortable huddle rooms and Zoom Room-enabled conference rooms, a spacious breakroom and kitchen with a coffee bar and snacks, and rooftop access to enjoy gorgeous views of Lake Union and Gas Works Park.

    Exciting challenges lie ahead-guided by our core values, we'll meet these challenges. Join us
  • Cascade Solutions

    Engineer for plant design in process engineering

    4 days ago

    Cascade Solutions Bellevue, United States

    What to expect? · You will develop and optimize mechanical system components and contribute to the determination of control concepts for SPS programming · You will be responsible for the design and project planning of fossil heating systems for glass melting furnaces, technical s ...

  • Coffman Engineers

    Process Engineer

    3 weeks ago

    Coffman Engineers Seattle, United States

    Company DescriptionAt Coffman Engineers, we serve as both prime consultant and subconsultant on projects large and small, including commercial, retail, healthcare, tribal, industrial, alternative energy and project/construction management. Incorporated in 1979, we have employees ...

  • Just-Evotec Biologics, Inc.

    Process Engineer

    3 weeks ago

    Just-Evotec Biologics, Inc. Seattle, United States

    Process Engineer. Master's in Chemical Engineering plus 24 months of exp. as Data Process Engineer, Data Scientist or Manufacturing Process Engineer. Salary $130,000.00/yr. plus comprehensive benefits package. Job Site: Redmond, WA. Send resume to: Just-Evotec Biologics, Inc. Att ...

  • Coffman Engineers

    Process Engineer

    6 days ago

    Coffman Engineers Seattle, United States

    Company Description · At Coffman Engineers, we serve as both prime consultant and subconsultant on projects large and small, including commercial, retail, healthcare, tribal, industrial, alternative energy and project/construction management. Incorporated in 1979, we have employ ...

  • Alpine Immune Sciences, Inc.

    Process Engineer

    2 weeks ago

    Alpine Immune Sciences, Inc. Seattle, United States

    Alpine Immune Sciences is seeking a highly motivated individual to join the CMC team as a Process Engineer (Upstream). This individual will be part of a team working to develop upstream processes that are robust, scalable, well characterized, and economical for clinical and comme ...

  • Alpine Immune Sciences, Inc.

    Process Engineer

    3 weeks ago

    Alpine Immune Sciences, Inc. Seattle, United States

    Alpine Immune Sciences is seeking a highly motivated individual to join the CMC team as a Process Engineer (Upstream). This individual will be part of a team working to develop upstream processes that are robust, scalable, well characterized, and economical for clinical and comme ...

  • Coffman Engineers

    Process Engineer

    2 weeks ago

    Coffman Engineers Seattle, United States

    Company Description · At Coffman Engineers, we serve as both prime consultant and subconsultant on projects large and small, including commercial, retail, healthcare, tribal, industrial, alternative energy and project/construction management. Incorporated in 1979, we have employ ...

  • Knewin

    Process Engineer

    2 weeks ago

    Knewin Seattle, United States

    Company Description · At Coffman Engineers, we serve as both prime consultant and subconsultant on projects large and small, including commercial, retail, healthcare, tribal, industrial, alternative energy and project/construction management. Incorporated in 1979, we have employ ...

  • Alpine Immune Sciences, Inc.

    Process Engineer

    6 days ago

    Alpine Immune Sciences, Inc. Seattle, United States

    Alpine Immune Sciences is a leading clinical-stage biopharmaceutical company dedicated to discovering and developing innovative, protein-based immunotherapies for autoimmune and inflammatory diseases. Exciting challenges lie ahead—guided by our core values, we'll meet these chall ...

  • Alpine Immune Sciences, Inc.

    Process Engineer

    3 weeks ago

    Alpine Immune Sciences, Inc. Seattle, United States

    Alpine Immune Sciences is a leading clinical-stage biopharmaceutical company dedicated to discovering and developing innovative, protein-based immunotherapies for autoimmune and inflammatory diseases. Exciting challenges lie ahead-guided by our core values, we'll meet these chall ...

  • Coffman Engineers, Inc.

    Process Engineer

    2 weeks ago

    Coffman Engineers, Inc. Seattle, United States

    Job Description · Job DescriptionCompany Description · At Coffman Engineers, we serve as both prime consultant and subconsultant on projects large and small, including commercial, retail, healthcare, tribal, industrial, alternative energy and project/construction management. Inco ...

  • Trelleborg Group

    Process Engineer

    3 weeks ago

    Trelleborg Group Seattle, United States

    Tasks and Responsibilities:Supports operation'stasks ranging fromdaily assignments tolong term projects. · Regularly interacts with shop floor employees, leads and supervisors to understand issues and identify technical solutions. Provides regular training to supervisors and sho ...

  • Trelleborg Group

    Process Engineer

    3 weeks ago

    Trelleborg Group Seattle, United States

    Tasks and Responsibilities:Supports operation'stasks ranging fromdaily assignments tolong term projects.Regularly interacts with shop floor employees, leads and supervisors to understand issues and identify technical solutions. Provides regular training to supervisors and shop fl ...

  • Infinity Systems

    Process Engineer

    4 days ago

    Infinity Systems Washington Terrace, United States

    Washington Terrace 'Die Nordgetreide GmbH & Co. KG is a rapidly expanding industrial company in Europe, specializing in the gentle processing of grains into food products since its founding in 1966. Currently, 500 employees (m/f/d) produce mill products and breakfast cereals at t ...

  • Blue Origin

    Process Manufacturing Engineer

    1 week ago

    Blue Origin Seattle, United States

    At Blue Origin, we envision millions of people living and working in space for the benefit of Earth. We're working to develop reusable, safe, and low-cost space vehicles and systems within a culture of safety, collaboration, and inclusion. Join our diverse team of problem solvers ...

  • Blue Origin

    Process Manufacturing Engineer

    1 week ago

    Blue Origin Seattle, United States

    At Blue Origin, we envision millions of people living and working in space for the benefit of Earth. We're working to develop reusable, safe, and low-cost space vehicles and systems within a culture of safety, collaboration, and inclusion. Join our diverse team of problem solvers ...

  • Harris Group

    Associate Process Engineer

    3 weeks ago

    Harris Group Seattle, United States

    Job Description · Job Description · Harris Group thrives on providing expert engineering for some of today's most complex challenges. We are creative in our approach by delivering multi-discipline services across a wide range of project types. We work on the most challenging pr ...

  • A-Alpha Bio

    Process Engineer I

    2 weeks ago

    A-Alpha Bio Seattle, United States

    A-Alpha Bio is an early-stage and rapidly growing drug discovery company headquartered in Seattle, WA. We are enabling the next generation of high-impact therapeutics by combining high-throughput synthetic biology to measure protein-protein interactions at scale with state-of-the ...

  • A-Alpha Bio

    Process Engineer I

    2 weeks ago

    A-Alpha Bio Seattle, United States

    A-Alpha Bio is an early-stage and rapidly growing drug discovery company headquartered in Seattle, WA. We are enabling the next generation of high-impact therapeutics by combining high-throughput synthetic biology to measure protein-protein interactions at scale with state-of-the ...

  • A-Alpha Bio

    Process Engineer I

    6 days ago

    A-Alpha Bio Seattle, United States

    A-Alpha Bio is an early-stage and rapidly growing drug discovery company headquartered in Seattle, WA. We are enabling the next generation of high-impact therapeutics by combining high-throughput synthetic biology to measure protein-protein interactions at scale with state-of-the ...