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    Research Associate in Genomics - Stanford, United States - InsideHigherEd

    InsideHigherEd
    InsideHigherEd Stanford, United States

    2 weeks ago

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    Description

    Research Associate in Genomics (Engreitz Lab, Life Science Research Professional 1)
    School of Medicine, Stanford, California, United States

    The Department of Genetics is seeking an experimental or hybrid research associate in genomics to join the Engreitz Laboratory at Stanford University. The main objective is to map the regulatory wiring of the human genome to discover genetic mechanisms of heart diseases.

    Lab Overview:

    • Focus on DNA regulatory elements in the human genome housing thousands of genetic risk variants for diseases.
    • Target is to reveal therapeutics by mapping the complex regulatory wiring connecting regulatory elements with genes in various cells.
    • Employ new experimental and computational genomics tools, biochemistry, and human genetics to understand heart disease mechanisms.

    The ideal candidate could be at any career stage and will work on experimental/computational projects to advance genomic technology and explore genetic disease variants.

    Specific Projects:

    • Develop CRISPR-based tools to map noncoding variant functions and enhancers.
    • Chart enhancer-promoter regulation in developing heart cells using single-cell CRISPR and epigenomic tools.
    • Understand enhancer-promoter biochemical specificity by creating enhancer-promoter combinations.
    • Create computational models to comprehend genetic heart disease regulation by noncoding variants.

    The Engreitz Lab offers a dynamic and interdisciplinary environment with access to state-of-the-art technologies. Additionally, a diverse and inclusive workplace encourages creative problem-solving approaches.

    Duties include:

    • Apply functional genomics technologies in human cells and disease models.
    • Recommend emerging technologies and approaches.
    • Conduct experiments essential for group success.
    • Interpret and present findings.
    • Maintain detailed records and contribute to protocols and publications.

    *- Other duties may be assigned.

    Desired Qualifications:

    • Degree in biology or related field.
    • 2+ years of research lab experience.
    • Proficiency in molecular biology techniques and cell culture.

    Education & Experience (Required):

    Bachelor's degree in a related scientific field.

    Knowledge, Skills and Abilities (Required):

    • General scientific principles understanding.
    • Ability to apply scientific knowledge to problem-solving.
    • Detailed record-keeping skills.
    • Computer proficiency and quick learning capability.

    Certifications & Licenses:

    None.

    Physical Requirements*:

    • Various physical tasks including standing, walking, lifting, and computer work.
    • Occasional work with hazardous materials and/or infectious diseases.
    • Ability to work under safety guidelines and in changing environments.

    *- The University offers reasonable accommodations for employees with disabilities.

    Working Conditions:

    • May involve exposure to bloodborne pathogens and work with hazardous materials.
    • Occasional extended work hours based on research requirements.

    Stanford University is an equal opportunity employer. Diversity is valued and individuals with disabilities can request accommodations during the application process.



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