- Execute and troubleshoot upstream and downstream process development experiments supporting next-generation AAV production
- Manage the flow of samples and data and perform analyses
- Assist in the design of experiments and interpretation of data
- Optimize workflows for assessing new constructs and modes of production
- Provide experimental design and executional support to team members in adjacent and related functions (e.g. clinical development programs, high throughput process development, etc.)
- Support research-to-development transition endeavors, including early-stage/pipeline molecular assessment activities
- Actively participate and support lab maintenance and continuous improvement initiatives
- Maintain accurate and detailed laboratory notebook and documentation
- Summarize and present data in group meetings and contribute to group discussions and team strategy
- Author technical reports and study memos.
- (AAV)+(UPSTREAM OR DOWNSTREAM) +(MAMMALIAN OR "CELL CULTURE" OR "CELL CULTURING")
- 2+ years of hands-on lab work on biotech industry
- Experience in process development: Upstream process development and/or mammalian cell culture OR Downstream process development/purification
- Bachelor's degree in STEM field.
- STEM degree with 2+ years of relevant industry experience; title/compensation will ultimately be commensurate with education, experience, and skillset
- Experience with suspension culture of mammalian cells in shake flasks and small stirred tank bioreactors
- Hands on experience in process development
- Independently motivated with ability to work in teams
- Ability to communicate clearly and concisely through oral presentation and technical writing
- Ability to leverage literature, internal and external resources to solve problems
- Desire to identify and advance the cutting edge
- Possess a growth mindset and the ability to thrive in a fast-paced, highly collaborative environment
- Preferred Qualifications:- Degree in biological or chemical engineering, biochemistry, or bio-related field
- Hands-on experience in downstream purification including chromatography and filtration
- Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing
- Experience with transfection-based processes
- Experience with upstream processes intensification e.g. fed batch and perfusion development, process-analytical technology (PAT)
- Experience with single-use technologies
- Experience with late-stage development.
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Senior Research Associate - Seattle, United States - Pyramid Consulting, Inc
Description
Immediate need for a talented SeniorResearch Associate (AAV Vector Biology and Molecular Optimization, Gene Delivery Process and Analytical Development) . This is a 12+ Months contract opportunity with long-term potential and is located in Seattle, WA (Onsite). Please review the job description below and contact me ASAP if you are interested.
Job ID:
Pay Range: $50 - $55/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).
Key Responsibilities:
Requirements and Technology Experience:
Our client is a leading Pharmaceutical organization and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.
Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, colour, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.