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    Senior Research Associate - Seattle, WA, United States - Sunrise Systems, Inc

    Sunrise Systems Inc background
    Scientific
    Description
    *Job Title*: *Senior Research Associate
    *Location: Onsite role in Seattle, WA**Duration: 12 months (With possible extension)
    *Position Type: Hourly contract Position (W2 only)

    *Top Skills: 2+ years of hands-on lab work on biotech industry

    Experience in process development:
    Upstream process development and/or mammalian cell culture OR Downstream process development/purification
    Bachelor's degree in STEM field

    *Job Description: The senior research associate/associate scientist will join the Gene Delivery Process and Analytical Development (GDPAD) organization supporting process development, production, and characterization of viral vectors, which are critical to generating groundbreaking cell therapies.


    The associate will join the AAV Platform Development team working on vector biology and molecular optimization initiatives intended to drive next-generation viral vector platform development.

    Specifically, in the pursuit of end-to-end assessment of Client technologies and approaches, the associate will seek to become highly proficient in upstream production and downstream purification of recombinant AAV, while gaining familiarity with AAV analytical methods and their interpretation in the context of AAV attributes and biology.

    The associate will also have the unique opportunity to be exposed to a wide range of highly Client molecular designs, and to work collaboratively with a range of different groups doing different types of rAAV development.

    *Responsibilities: Execute and troubleshoot upstream and downstream process development experiments supporting next-generation AAV production
    Manage the flow of samples and data and perform analyses
    Assist in the design of experiments and interpretation of data
    Optimize workflows for assessing new constructs and modes of production
    Provide experimental design and executional support to team members in adjacent and related functions (e.g. clinical development programs, high throughput process development, etc.)
    Support research-to-development transition endeavors, including early-stage/pipeline molecular assessment activities
    Actively participate and support lab maintenance and continuous improvement initiatives
    Maintain accurate and detailed laboratory notebook and documentation
    Summarize and present data in group meetings and contribute to group discussions and team strategy
    Author technical reports and study memos

    *Basic Qualifications: STEM degree with 2+ years of relevant industry experience; title/compensation will ultimately be commensurate with education, experience, and skillset
    Experience with suspension culture of mammalian cells in shake flasks and small stirred tank bioreactors
    Hands on experience in process development
    Independently motivated with ability to work in teams
    Ability to communicate clearly and concisely through oral presentation and technical writing
    Ability to leverage literature, internal and external resources to solve problems
    Desire to identify and advance the cutting edge
    Possess a growth mindset and the ability to thrive in a fast-paced, highly collaborative environment

    *Preferred Qualifications: Degree in biological or chemical engineering, biochemistry, or bio-related field
    Hands-on experience in downstream purification including chromatography and filtration
    Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing
    Experience with transfection-based processes
    Experience with upstream processes intensification e.g. fed batch and perfusion development, process-analytical technology (PAT)
    Experience with single-use technologies
    Experience with late-stage development

    *The hourly rate for this position is between $54-$59 per hour.

    *Compensation: Factors which may affect starting pay within this range may include [geography/market, skills, education, experience and other qualifications of the successful candidate].

    *Benefits: Sunrise offers ACA compliant medical coverage/dental insurance/vision insurance to all employees. We also offer Sick time benefits as required per State regulations.

    *IND\_EGNIT*Job Type: Contract


    Pay:
    $ $59.00 per hour


    Schedule:

    • 8 hour shift

    Education:

    • Bachelor's (Required)

    Experience:

    • Gene editing: 3 years (Required)
    Viral Vector: 3 years (Required)

    • Cell culture: 3 years (Required)

    Work Location:
    In person


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