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Research Scientist Director
4 weeks ago
The University of Texas MD Anderson Cancer Center San Francisco, CA, United StatesPrincipal Scientist/Director, Chemical Biology · General Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challen ...
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Research Scientist Director
4 weeks ago
Generalproximity San Francisco, CA, United StatesGeneral Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable to other m ...
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Principal Scientist/Director, Chemical Biology
6 hours ago
The University of Texas MD Anderson Cancer Center San Francisco, United StatesJob Title: Principal Scientist/Director, Chemical Biology · Job Number: · 78085 · Location: · San Francisco, CA,US · Job Description · tl;dr · General Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discover ...
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General Proximity San Francisco, United Statestl;dr · General Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable t ...
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Director, Clinical Scientist
4 weeks ago
Human Immunology Biosciences South San Francisco, United StatesJOB TITLE: Director, Clinical Science · DEPARTMENT: Clinical Development · LOCATION: South San Francisco, California · TYPE: Full-Time (Onsite / Hybrid) · Are you an experienced scientist with clinical research experience in kidney and/or immune-mediated diseases? Join HI-Bio, In ...
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Principal Scientist/Director, Chemical Biology
4 weeks ago
The University of Texas MD Anderson Cancer Center San Francisco, CA, United StatesJob Title: Principal Scientist/Director, Chemical Biology · Job Number: 78085 · Location: San Francisco, CA,US · Job Description · tl;dr · General Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discovery en ...
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Principal Scientist/Director, Chemical Biology
3 weeks ago
General Proximity San Francisco, United Statestl;dr · General Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable to ...
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Principal Scientist/Director, Chemical Biology
4 weeks ago
Generalproximity San Francisco, CA, United Statestl;dr · General Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable t ...
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Third Rock Ventures San Francisco, United StatesTHE COMPANY · Septerna is a biotechnology company with a vision to become the industry-leading G protein-coupled receptor (GPCR)-focused R&D company with a portfolio of life-changing medicines. The company's Native Complex Platform recapitulates GPCRs with their native structure, ...
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Clinical Scientist Director
2 weeks ago
Corcept Therapeutics Menlo Park, United StatesCorcept is leading the way in the research and development of cortisol modulators, molecules that regulate cortisol activity at the glucocorticoid receptor (GR). To date, we have discovered more than 1,000 selective proprietary cortisol modulators. · In 2012, we received FDA appr ...
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Director, Clinical Scientist
3 weeks ago
RemeGen Biosciences South San Francisco, United States OTHERORGANIZATION · RemeGen Biosciences is a biopharmaceutical company, focusing on the discovery and development of innovative medicines for the treatment of cancer and autoimmune diseases, based in South San Francisco, California, and Rockville, Maryland. By leveraging our deep insi ...
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Nurix Therapeutics San Francisco, United States Full timeNurix Therapeutics ) is a private biopharmaceutical company developing novel small molecule immune modulators for the treatment of cancer and autoimmune diseases. Based on the successful progress of our R&D platform, including expertise in medicinal chemistry, immune cell biology ...
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Northreach San Francisco, United StatesNorthreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalised recruitment experience for clients and candidates, and to create a positive work environment that encourages ...
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Director, Clinical Scientist
2 weeks ago
Remegen Biosciences, Inc. South San Francisco, United StatesJob Description · Job DescriptionORGANIZATION · RemeGen Biosciences is a biopharmaceutical company, focusing on the discovery and development of innovative medicines for the treatment of cancer and autoimmune diseases, based in South San Francisco, California, and Rockville, Mary ...
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Genentech South San Francisco, United StatesThe Position · We advance science so that we all have more time with the people we love. · The Translational Medicine department at Genentech is seeking a highly motivated and innovative scientific leader for our IBD portfolio. The Director is responsible for the scientific, stra ...
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Frontier Medicines South San Francisco, United StatesJoin Frontier Medicines on an exciting journey as our newest Principal Scientist/Associate Director, CMC Development located at our South San Francisco office. · As a crucial member of our team, reporting directly to the Head of CMC, you'll play an integral role in advancing our ...
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Frontier Medicines South San Francisco, United StatesJob Description · Job DescriptionJoin Frontier Medicines on an exciting journey as our newest Principal Scientist/Associate Director, CMC Development located at our South San Francisco office. · As a crucial member of our team, reporting directly to the Head of CMC, you'll play ...
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Associate Director, Safety Scientist
1 week ago
BeiGene Emeryville, United States**General Description:** · _The Associate Director, Safety Scientist supports assigned compounds in conjunction with Product Safety Leads (PSLs) and leverages clinical and scientific expertise to perform signal detection, evaluation of safety data, assessment of safety risks, re ...
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Cytokinetics, Incorporated South San Francisco, United StatesCytokinetics is a late-stage, specialty cardiovascular biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators and next-in-class muscle inhibitors as potential treatments for debilitating diseases in which cardiac muscle p ...
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Director/Sr. Principal Scientist, Cell Therapy
2 weeks ago
Genentech South San Francisco, United StatesThe Position · Summary · This position will play a key role in the newly established department of Cell Therapy in gRED Research Biology. Reporting directly to the Head of Cell Therapy (Vice President, GE level), the selected candidate will assume accountability for the developme ...
Research Scientist Director - San Francisco, CA, United States - MBC BioLabs
Description
General Proximity is a seed-stage startup developing the next generation of induced-proximity medicines.Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable to other modalities for decades.
We are seeking first-rate chemical biologiststo help us pioneer this uncharted frontier of drug discovery.A long-standing challenge in drug discovery is the development of molecules capable of modulating difficult or "undruggable" targets. General Proximity is a seed-stage drug discovery company developing a novel platform technology to solve this problem.
Historically, the development of technologies that allow one to push new buttons in biology has been an incredibly fertile field for the discovery of new medicines[2 , 3 , 4], and our technology holds the same promise.
We are seeking an experienced chemical biologist to be a founding member of our Platform/Drug Discovery Team.In this position, you will work in close conjunction with our Biology Team in the development of our core drug discovery technology and the generation of a completely novel class of therapeutics.
Your responsibilities will include supervising synthetic efforts with our CROs, designing and performing both low and high-throughput screening assays, managing compound libraries, performing mechanistic studies on lead drug molecules, and spearheading forays into new disease areas.
Drug discovery is doubly so. PhD in Chemical Biology, Medicinal Chemistry, Pharmacology, or related field.Experiencing leading and managing highly effective teams in the industry.
Deep understanding of small-molecule drug discovery and its relationship to human disease.
PPI techniques, e.g., Platform development
Compound management
PTM analysis, chemo-proteomic target deconvolution, etc
Computational drug discovery experience
Prior experience on teams that have successfully advanced research to the clinic
We are looking for candidates who will bring a strong sense of ownership to drive their project areas forward, and we believe that you deserve to be compensated accordingly.
~401(k) retirement plans.
~ Located in the MBC BioLabs at 135 Mississippi Street, an entrepreneurial hub full of the best scientists and operators the Bay Area has to offer. Our lab is a very short walk from the 22nd St Caltrain Station and a number of wonderful restaurants and cafés.
We won't drag you through unnecessary meetings or email you at 7 PM on a Saturday. Strong Communication. We like well-written documents over PowerPoints, OKRs over vague mission statements, and weekly one-on-ones over yearly reviews.
We believe that clarity of writing reflects clarity of thinking and that the benefits of well-written documentation in a scientific environment are innumerable: democratization of ideation and decision-making, increased reproducibility, quicker scaling and onboarding, and better company-wide alignment, to name a few.
Applications from candidates of diverse backgrounds, women, and members of underrepresented minority groups are particularly welcomed.
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