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    Application Scientist - Boston, MA, United States - The University of Texas MD Anderson Cancer Center

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    Full time
    Description

    Job Title:
    Sr. Scientist, Analytical

    Job Number: 34039


    Location:
    Boston,MA

    Job Description


    We are seeking an Analytical Development Bioassay Scientist to be responsible for developing cell-based and ELISA potency assays for product testing/characterization for our clients Boston-based lab.

    This individual will be an important member of the TechOps team, responsible for developing assays and testing various molecules at all stages of product development.

    This role will report to the Vice President of Bioanalytical Development.

    Responsibilities

    Key Responsibilities

    Develop cell-based bioassays and ELISAs suitable for validation and transfer to GMP testing labs

    Build out/equip lab to establish robust bioassay/potency testing capabilities in-house (non-GMP)

    Perform potency testing of protein-based drug candidates to support development activities, stability studies, and molecule characterization

    Oversee the qualification/validation and transfer of assays

    Interpret bioassay data, troubleshoot assays and take part in lab investigations as needed

    Author study protocols and reports

    Work closely with Manufacturing & Development partners within TechOps, as well as external stakeholders, to execute bioassay/potency testing activities according to program needs

    Ideal Candidate

    Advanced degree, or equivalent experience, in a relevant discipline (e.g., cell biology, or related field)

    5+ years of experience developing cell-based bioassays and ELISAs used to quantitatively test the potency of complex biological molecules

    Expertise/competence with additional analytical techniques such as HPLC, spectrophotometry, and capillary electrophoresis is desired

    Ability to work full time on-site at our Boston-based laboratory with minimal direct supervision

    Excellent communication skills with an ability to collaborate effectively across functional lines

    Ability to work and multi-task in a fast-moving organization

    Availability to participate in calls across multiple international time zones

    Ability and willingness to travel up to eight times a year

    Required Skills

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