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senior director, rna therapeutics
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Clinical Trial Manager
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Ascidian Therapeutics Boston, United StatesAbout us: · Ascidian is redefining the treatment of disease by rewriting RNA. · Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow fro ...
Program Director, RNA Therapeutics - Boston, United States - Ginkgo Bioworks
Description
Our mission is to make biology easier to engineer.Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe's growing challenges in health, energy, food, materials, and more.
Our bioengineers make use of an in-house automated foundry for designing and building new organisms.Ginkgo's mission is to make biology easier to engineer.
We are constructing, editing, and redesigning the living world to answer the globe's growing challenges in health, energy, food, materials, and more.
Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Today, our foundry is developing over 40 different organisms to make different products across multiple industries.
Ginkgo is continuously crossing new frontiers of biological engineering, and we have a record of delivering to our partners what was (until recently) thought impossible.
Now, our expansion into mammalian cell engineering promises to push our boundaries even further, and so we're looking for curious, creative, and driven pioneers in this field.
This is an exciting time, and new Mammalian team leaders have a great opportunity to impact the direction and growth of the team.
We're searching for a remarkable Program Director to lead programs to deliver success to our partners in the area of RNA therapeutics.
a deep technical background in RNA biology and understands how to deploy various toolkits including cell engineering, genetics and functional genomics, NGS, and high-throughput screening approaches to design better RNA sequences that support long-term or tissue-specific translation.
or
in vivo ) and its function. Knowledge of
in vitro
transcription methods for generating RNAs and familiarity with RNA-associated immunogenicity is important. Demonstrated experience managing interdisciplinary teams to deliver technical milestones on timelines is a requirement. Internal title Senior Mammalian Engineer 3.
Is this the role for you? Your deep technical understanding should enable you to offer technical solutions to potential partners' challenges and then work to deliver those solutions.
As a driven and organized team member, you will need to be flexible and able to re-prioritize with the changing demands of a fast-paced environment.
Team members will be inspired by your commitment to technical excellence and delivery.Please note:
this role could be based in either our Seaport or Cambridge locations, but requires some flexibility to occasionally be present at the other location.
Responsibilities:
Provide technical direction and guidance on improving partner RNA therapeutics to insure project success
Support resource management and project planning across the broader project team
Communicate project and team performance to leadership and external customers
Identify and help develop new technologies to drive next-generation RNA platform development
Provide technical support, including scientific strategy and messaging, to Ginkgo's Commercial Team, and directly interface with current and potential external partners
Provide feedback on feasibility of various approaches to senior management and key internal stakeholders
Grow, supervise, and mentor a small team of researchers working on RNA therapeutic-specific challenges
Coordinate efforts across interdisciplinary teams within Ginkgo's foundry and 3rd party vendors
Assist with shaping Ginkgo's overall direction as a company and support its evolving needs, as necessary
Minimum Requirements
PhD or equivalent experience in molecular biology, bioengineering, synthetic biology, or related field
8+ years of research experience post-PhD
Direct experience and technical leadership in projects investigating RNA sequence-structure-function relationships in the context of translation, stability, catalysis, interference, or any other RNA process.
Proven track record of leading successful teams and mentoring multiple team members
Strong molecular biology expertise, with significant experience in mammalian cell culture and familiarity with next-generation sequencing technologies
Ability to work with interdisciplinary teams in a fast-paced, high-growth environment
Excellent communication and organization skills, with the ability to effectively convey project plans and complex technical information to a wide range of internal teams, executive leadership, and external partners
Preferred Capabilities and Experience
3 years of industry experience in RNA biology (need not be directly therapeutics) preferred
Direct experience and technical leadership in generating and screening large libraries of RNA elements to elucidate sequence-structure-function relationships between those elements and RNA processes (ie catalysis, translation, stability, interference, etc)
Experience with ribosomal profiling a plus
Computational background in RNA structure / function
Ability to effectively interface with custom and commercial LIMS systems, and utilize software tools for sample and workflow managemen
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We also feel that it's important to point out the obvious here - there's a serious lack of diversity in our industry, and that needs to change.
Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team.
Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.
We're developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can - and will - impact people around the world.
We care about how our platform is used, and having a diverse team to build it gives us the best chance that it's something we'll be proud of as it continues to grow.
Therefore, it's critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.
It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees, employment applicants, and EOE disability/vet.
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Ginkgo may share my information with such third-party service providers in connection with my application and for the start of employment.
By submitting this job application, I am acknowledging that I have reviewed and agree to Ginkgo's
as well as the privacy policies of the third-party service providers used by Ginkgo's associated with the application process.
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