- Collaborate closely with a scientist on CAR T cell generation process development and optimization.
- Assist in testing various methods, such as viral-based immune cell engineering to facilitate high-throughput CAR T cell manufacturing.
- Troubleshoot technical difficulties encountered during experiments.
- Work with ab and gd T cells, conducting experiments to evaluate the performance of different CAR designs.
- Conduct data analysis, interpretation, and presentation using relevant software tools such as Microsoft Office, GraphPad PRISM, FlowJo and others.
- Document detailed experimental procedures, results, and observations in electronic laboratory notebooks (ELN) to maintain accurate records.
- Foster collaborative teamwork by actively participating in lab meetings, sharing ideas, and contributing to the optimization of laboratory protocols and techniques.
- Maintain a strong commitment to safety protocols and adhere to laboratory guidelines while ensuring quality in execution of experiments.
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Co-Op, Cell Therapy CAR Screening - Spring House, United States - Johnson & Johnson
Description
At Johnson & Johnson, we believe health is everything.Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.
Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.
Learn more at
Johnson & Johnson Innovative Medicine is recruiting for a Co-op, Cell Therapy CAR Screening and Lead Selection within the Cell Therapy Platform and Discovery Research Team for our site in Spring House, PA.
The Cell Therapy Platform and Discovery Research Team within the Therapeutics Discovery (TD) division of J&J Innovative Medicine undertakes research and development of Chimeric Antigen Receptor (CAR)-directed cell therapies.
The Cell Therapy CAR Screening and Lead Selection Team is responsible for the discovery and optimization of CAR designs to deliver highly efficacious autologous and allogeneic CAR T cell therapy products.
In this position, the co-op will have the opportunity to contribute to the cutting-edge field of CAR T cell therapy and work closely with a highly skilled scientist on CAR T cell manufacturing to support therapeutic programs across hematological and solid tumors.
They will gain hands-on experience working with both alpha-beta (ab) T cells and gamma-delta (gd) T cells, as well as investigate various methods to enable high-throughput CAR T-cells generation.
The research will focus on the identification of the most promising CAR design candidates for cell therapy applications.The co-op student will: