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    Scientist - In Vitro Pharmacology - San Francisco, United States - BioSpace

    BioSpace
    BioSpace San Francisco, United States

    1 day ago

    BioSpace background
    Description
    Job Details

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

    At DICE Therapeutics, a wholly owned subsidiary of Eli Lilly & Company, we design and develop innovative therapies in immunology for patients with debilitating disease. We are seeking to create a future where convenient oral medicines with biologic-like efficacy are available to patients with serious medical conditions, we are developing oral alternatives to medicines currently limited to injectable forms.

    The successful candidate will assume the responsibility of independently planning and implementing experiments using various biophysical and biochemical techniques. These will include a variety of biophysical binding assays (SPR, BLI, DSF), biochemical potency assays (absorbance and fluorescence-based assays such as HTRF, AlphaScreen/Lisa, ELISA, fuorescent polarization, and SPR- or BLI-based PPI) and cell assays with engineered cell lines. Working in a multidisciplinary team, this candidate will support SAR and advance DICE's small molecule discovery programs through their data production and analysis.

    Are you looking to join an innovative company working on pioneering science? Apply today to join the DICE team
    Key Responsibilities:
    • Conducting detailed analysis of small molecule binding using biophysical methods and direct binding assays, especially SPR, BLI, DSF/nano-DSF, etc.
    • Performing key experiments to support drug discovery using biophysics, biochemistry, and cell biology
    • Generating high-quality, reproducible data and investigating binding and mechanism of inhibition by using a suite of analytical instruments, supported by liquid handling, laboratory automation and advanced data analysis tools
    • Identifying and developing new assays as projects require
    • Communicating experimental results and analysis to project teams
    Minimum Qualifications:
    • B.S. or MS in science related field
    • 2+ years of experience
    Additional Preferences:
    Demonstrated prior experience with at least 2 of the following techniques and technologies:
    • Biacore
    • Octet
    • Mammalian tissue culture
    • Liquid handling systems and automation such as Biomek, Hamilton, Integra,Tecan, or Echo liquid dispensers or similar
    • Data analysis software such as Prism, Dotmatics or similar
    • Creativity, a high degree of independence, and passion to learn new skills
    • Strong collaboration, communication, and record-keeping skills
    Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

    Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

    Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.

    #WeAreLilly
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