- Purifying proteins and antibodies and generation of protein/antibody conjugates
- Optimization of bioconjugation across modalities (e.g. conjugation of small molecules, peptides, oligonucleotides to protein and antibodies)
- Optimization of bioconjugate delivery (e.g. increasing potency, efficacy, and tissue selectivity)
- Characterizing protein and conjugate structure, stability, and solution properties using various biochemical and biophysical approaches
- Embrace and celebrate diversity by using a relevant and unique background and set of experiences to provide new ideas to deliver innovative solutions drugging novel targets. Strong communication (oral and written), organizational, and leadership skills are expected.
- Bring new and useful concepts, methods, and ideas for how research can be improved and share these to make our group better. Basic Qualifications
- PhD in biochemistry, protein chemistry, or related field. OR
- MS in related field and 5+ years of relevant industrial experience. Additional Skills and Preferences
- Hands-on experience in protein purification, bioconjugation, and characterization of proteins and conjugates in academic or industrial settings.
- Strong core proficiency in protein biochemistry, knowledge of protein structure-function relationship, and experience in biochemical analyses are required.
- Demonstrated self-initiative and appropriate risk-taking behaviors.
- Exceptional problem solving and decision-making skills.
- Must be able to work productively and collaboratively in an interdisciplinary team environment.
- Ability to prioritize multiple activities and thrive in a setting that requires quick movement between scientific challenges and comfort with ambiguity.
- An active scientific curiosity and interest for complementary disciplines within the pharmaceutical industry.
- Effective oral and written communication skills Additional Information
- Location: Indianapolis, IN Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups. #WeAreLilly -
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Advisor - Biotechnology Research - Indianapolis, United States - Eli Lilly and Company
Description
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Lilly's Biotechnology Discovery Research (BioTDR) organization has a track record for delivering novel biotherapeutic medicines to advance into clinical research in key areas of unmet medical need including diabetes, oncology, immunology, neuroscience, and others.
This position is within the Lead Optimization Team of BioTDR organization. We are responsible for generating, characterizing, and optimizing biotherapeutics from lead generation to lead optimization and preclinical development. We are searching for a highly motivated and creative research scientist with a PhD degree in biochemistry, protein chemistry or related field to join a talented multidisciplinary team. This position provides an outstanding opportunity to transform ideas to clinical candidates.
Responsibilities
