- Senior Scientist II typically requires Bachelors, Masters, or Ph.D. with 12+ (B.S.), 10+ (M.S.), and 4+ (Ph.D.) years of experience in pharmaceutical or related industry. Preferred educational backgrounds include but are not restricted to Pharmaceutical Sciences, Pharmaceutical Engineering, Chemical/ Biomedical Engineering, and Materials Science.
- Fundamental understanding of biopharmaceutics as it relates to drug absorption across routes of administration.
- Familiarity and preferred hands-on experience in physicochemical property assessment related to understanding CMC developability profile and potential risk mitigation strategies. Techniques of interest include, but are not limited to: chromatography, x-ray diffraction, thermal analysis, microscopy, biophysical characterization techniques, etc.
- Experience developing and characterizing drug delivery systems to improve the bioperformance of small molecules, PROTACs, and/or peptides.
- Knowledge of preclinical and clinical formulation development principles relevant to chemically synthesized molecules across routes of administration.
- Excellent self-management and organizational skills.
- Demonstrated strong communication skills and ability to clearly communicate theories and concepts, influence others without authority, and drive technical excellence. Key Competencies
- Builds strong relationships with peers and cross-functional partners to enable higher performance.
- Learns fast, grasps the "essence, and can change course quickly where indicated.
- Connects ideas from disparate fields, integrates data and information quickly, and takes risks to achieve the highest performance.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: - The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
- This job is eligible to participate in our long-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law. AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
-
AbbVie North Chicago, United StatesJob Description · Job DescriptionCompany Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives acr ...
-
Visiting Research Specialist
1 week ago
University of Illinois Chicago, United States**Visiting Research Specialist - COIP** · **Hiring Department**: COIP · **Location**: Chicago, IL USA · **Requisition ID**: · **Posting Close Date**: May 21, 2024 · **About the University of Illinois Chicago** · UIC is among the nation's preeminent urban public research universi ...
-
Pharmacy Buyer
1 week ago
Rush University Chicago, United States**Location**:Chicago, IL · **Hospital**:RUSH University Medical Center · **Department**:Pharmacy Services · - Administration · **Work Type**:Full Time (Total FTE between 0.9 and 1.0) · **Shift: Shift 1** · **Work Schedule**:8 Hr (8:00:00 AM - 4:30:00 PM) · Summary: · The Pharmacy ...
-
Amazon Dsp Delivery Associate
6 days ago
Amazon DSP Chicago, United States**Urgently Hiring** · 1-Eleven Logistics, LLC is an Amazon Delivery Service Partner looking for enthusiastic, team players to deliver Amazon packages. **Delivery Associates** strive to get every Amazon order to the customer's door on-time. We offer full and part-time opportunitie ...
-
Unarmed Security Officer
1 week ago
THE LOSS PREVENTION GROUP, INC. Chicago, United StatesINDJM · Have a passion for service - we have just the opportunity for you · Did you know that Security is now a True Valued Profession? · Seeking Work Life Balance? · Find an exciting career path at Metro One Loss Prevention Service Group · We offer: · Weekly Pay · Competitive Be ...
-
Van Driver
6 days ago
West Marine Chicago, United States**Job Summary**: · Van Drivers coordinate order selection, order packing and shipment, providing the store team with timely information as needed. Load / unload van deliveries as directed, perform returns as per standards. Van Driver will deliver marine equipment and accessories ...
-
Research Professional
1 week ago
The University of Chicago Chicago, United StatesDepartment · BSD PED - Hematology, Oncology, and Stem Cell Transplantation - LaBelle Lab · About the Department · Section of Pediatric Hematology/Oncology provides care for patients and families with acute and chronic medical conditions, or other hematologic diseases, requiring s ...
-
Yard Jockey
1 day ago
Reyes Beverage Group Chicago, United StatesOverview: · Come join the largest beer distributor in the United States and be a part of our Performance Promise where we live out our company's purpose of connecting customers, consumers and brands every day, everywhere we operate. · At Reyes Beverage Group, we're proud to be th ...
-
Lead Business Consultant
1 day ago
HCSC Chicago, United StatesAt HCSC, we consider our employees the cornerstone of our business and the foundation to our success. We enable employees to craft their career with curated development plans that set their learning path to a rewarding and fulfilling career. · Come join us and be part of a purpos ...
-
Manager Provider Reimbursement
1 week ago
HCSC Chicago, United StatesAt HCSC, we consider our employees the cornerstone of our business and the foundation to our success. We enable employees to craft their career with curated development plans that set their learning path to a rewarding and fulfilling career. · Come join us and be part of a purpos ...
-
Junior Data Analyst
2 days ago
Kooth USA Chicago, United States**Junior Data Analyst | Chicago, IL, Hybrid** · - About Us _ · Kooth is a fast-growing organization with a social purpose. After 20 years of successful services in the UK, we are rapidly expanding in the United States · **OUR MISSION**: To provide welcoming and effective digital ...
-
Product Implementation Consultant
1 week ago
HCSC Chicago, United StatesAt HCSC, we consider our employees the cornerstone of our business and the foundation to our success. We enable employees to craft their career with curated development plans that set their learning path to a rewarding and fulfilling career. · Come join us and be part of a purpos ...
-
Program Manager Ii
1 week ago
bp Chicago, United StatesJob summary · **Entity**: · Customers & Products · **Job Family Group**: · IT&S Group · bp pulse, bp's electric vehicle (EV) charging business, is working to simplify electrification by providing fast, reliable charging solutions for both consumers and commercial fleets across Am ...
-
Assoc Developer
6 days ago
HCSC Chicago, United StatesAt HCSC, we consider our employees the cornerstone of our business and the foundation to our success. We enable employees to craft their career with curated development plans that set their learning path to a rewarding and fulfilling career. · Come join us and be part of a purpos ...
-
Msh Nr Med Surg Os6 Staff Nurse
1 week ago
Sinai Chicago Chicago, United States**6 North (Oncology / Cancer Services)** · Mount Sinai Hospital's Cancer Program includes our Ambulatory Chemotherapy Infusion Unit (nine-chairs), the Hematology/Oncology Clinic and a 28 bed inpatient unit on 6 North. Our Cancer Program is accredited by the American College of Su ...
-
Origination Analyst
1 week ago
bp Chicago, United StatesJob summary · **Entity**: · Trading & Shipping · **Job Family Group**: · Supply & Trading Group · The Central Marketing & Origination team is key for Trading & Shipping - developing and delivering third party business opportunities. The Origination Analyst will work with the trad ...
-
Warehouse Order Picker
2 days ago
Reyes Beverage Group Chicago, United StatesOverview: · Come join the largest beer distributor in the United States and be a part of our Performance Promise where we live out our company's purpose of connecting customers, consumers and brands every day, everywhere we operate. · At Reyes Beverage Group, we're proud to be th ...
-
HCSC Chicago, United StatesAt HCSC, we consider our employees the cornerstone of our business and the foundation to our success. We enable employees to craft their career with curated development plans that set their learning path to a rewarding and fulfilling career. · Come join us and be part of a purpos ...
-
Warehouse Associate I
6 days ago
National Performance Warehouse Chicago, United States**NPW** is seeking a highly organized and metrics driven Warehouse Associate to join our team. If you enjoy mentoring a team and helping to create processes to improve efficiencies, then this is a great opportunity for you. · **Who is NPW?** · NPW is a leading independent automot ...
-
Offer & Deal Lead
6 days ago
bp Chicago, United StatesJob summary · **Entity**: · Customers & Products · **Job Family Group**: · Strategic Planning & Business Development Group · Want to be part of something Electrifying? bp pulse is one of the fastest growing EV charging networks globally, and we need YOU to help us on our adventur ...
Senior Scientist II, Molecular Profiling and Drug Delivery - North Chicago, United States - AbbVie
Description
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.
Job Description
The Molecular Profiling and Drug Delivery (MPDD) function within the Small Molecule CMC organization is accountable for a broad range of deliverables across various stages of drug discovery and development. During lead optimization and through candidate selection, MPDD scientists utilize state of the art automation and computational tools supported by expertise in biopharmaceutics, drug delivery, and solid-state chemistry to collaborativelyprogress candidates with higher probability of success intodevelopment and advise clinical formulation strategy. From candidate selection through clinical proof of concept and product launch, MPDD scientistswork in cross functional teams to identify the commercial solid form of the active pharmaceutical ingredient (API) and establish structure-property-performance correlations to help deliver robust commercial processes and align control strategies across drug substance and product. They also transition drug substance isolation processes and relevant physical characterization methods to commercial manufacturing sites and work within teams to ensure successful regulatory submissions.
Drug Delivery scientists within AbbVie's MPDD organization work collaboratively with other functions within Development Sciences and Discovery to conduct developability assessment to select molecules with higher probability of success for clinical development and eventual commercialization. This includes profiling of physicochemical properties, development of preclinical formulations, identifying solutions to in vivo absorption challenges, and advancement of novel drug delivery strategies across multiple routes of administration that are aligned with program target product profiles and downstream partners. Modalities of interest include traditional small molecules as well as complex chemically synthesized modalities such as PROTACs and peptides. In this role, you will work in cross-functional teams in matrixed environments and engage in multidisciplinary problem solving.
Job Description
AbbVie's MPDD organization is seeking a highly motivated, talented, and creative scientist with expertise and some experience in pharmaceutical sciences and drug delivery for a Senior Scientist II position. The primary role of this position is to serve as an MPDD project leader on discovery programs, leading CMC developability assessment for emerging molecules on small molecule pipeline programs. This role will also entail contributing towards developing our drug delivery capabilities with a focus on complex chemically synthesized modalities such as PROTACS and peptides. This person will be working collaboratively with discovery and development partners across disciplines to improve delivery of these modalities and advance molecules to clinical development with improved developability profiles. The desired candidate will have a strong background and hand-on experience in the areas of physicochemical and/or biophysical properties and their impact on developability, preclinical and/or clinical formulation, biopharmaceutics, and drug delivery concepts relevant to small molecules and peptides.
Qualifications
