- Develop and implement Toxicology strategies and build infrastructure to support discovery and development programs using internal resources and CROs
- Recruit scientists and Director level leaders to build and manage a team to support Toxicology strategy across the three Altos sites (Toxicology, Discovery and Toxicological Pathology, Nonclinical Operations), to ensure delivery of high quality data packages in support of target validation through to regulatory filings
- Conduct target safety assessments for early therapeutic targets, and work closely with laboratories in the Institutes of Science to understand and derisk the safety of targets early on
- Plan and execute in vitro safety screens to lead optimize small molecules, ASOs and gene therapy vectors
- Work closely with CROs to coordinate and manage external toxicology studies
- Represent Toxicology in multifunctional discovery and early development project teams
- Effective cross-functional collaboration, especially with Institutes of Science, In Vivo Pharmacology and DMPK, in the optimization of drug leads and candidates
- Contribute to the cross-functional review of regulatory documents and author and review Toxicology sections for relevant regulatory documents
- Recommend, initiate, lead and champion new innovations to ensure relevant cutting-edge science is applied to project related issues
- Create and foster strong partnerships with groups at the Institutes of Science
- Contributes to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion
- PhD in Toxicology, Pharmacology or related sciences (or DVM) and a minimum of years of industry experience in Pathology/Toxicology
- Deep expertise in Drug Development, with a proven track record of working in cross functional teams to bring drugs from Discovery to Clinic
- Track record of regulatory filings and participation in regulatory interactions
- Strong scientific aptitude and ability to implement investigative strategies to elucidate mechanisms of toxicity; expertise in Discovery Toxicology, including small molecule lead optimization
- Demonstrated ability to build, manage and lead groups responsible for supporting Toxicology deliverables in a team setting
- Demonstrated understanding and established level of expertise employing preclinical models
- Strong knowledge and agility in study design and data interpretation and in the integration of Toxicology studies in the drug progression paradigm, as well as in the incorporation of safety endpoints in pharmacology studies
- 3Rs-centered, welfare-oriented approach to animal-based research
- A critical thinker with the ability to analyze possibilities and solutions and make pragmatic trade-off
- Clear and influential communicator: exceptional influencing skills that demonstrate strong thought partnership and create effective relationships with internal and external groups and individuals
- Experience working across diverse therapeutic modalities, including small molecules, biotherapeutics, nucleic acid therapeutics, and gene therapy is highly desirable
- Project team leadership experience in the discovery space is highly desirable
- Background/degree in pathology preferred.
- Senior Director: $324,700 - $439,300
- Executive Director: $357,000 - $483,000
- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice )
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.
-
Senior Director
3 weeks ago
Pattern Energy San Francisco, United StatesOverview · Pattern Energy is a leading renewable energy company that develops, constructs, owns, and operates high-quality wind and solar generation, transmission, and energy storage facilities. Our mission is to transition the world to renewable energy through the sustainable d ...
-
Senior Director/Director
3 weeks ago
Kearns & West Inc San Francisco, United StatesJob Description · Job DescriptionKearns & West · Senior Director/Director · San Francisco, California · About the Job · THE ORGANIZATION · Kearns & West, Inc. is a stakeholder engagement, communications, and collaborative solutions firm. Our staff is passionate about engaging com ...
-
Senior Director
2 weeks ago
HI-Bio San Francisco, United StatesJOB TITLE: · Director/Senior Director, Medical AffairsDEPARTMENT: · Clinical DevelopmentLOCATION: · South San Francisco, CaliforniaTYPE: · Full-Time (Hybrid) · Is this your next job Read the full description below to find out, and do not hesitate to make an application. · A ...
-
Senior Director of Accounting
1 week ago
Reneris San Francisco, United StatesA non-profit organization that for nearly 40 years has been at the leading edge of practical and innovative solutions to address the homelessness crisis in the San Francisco Bay Area and one of the region's largest, most comprehensive providers of essential services to individual ...
-
Senior Director
1 day ago
Innovaccer San Francisco, United StatesAbout the Role · As a Senior Director of Product Marketing at Innovaccer, you will play an instrumental role in launching and promoting a suite of AI-enabled products that are transforming healthcare. Innovaccer is the trusted AI technology partner for leading healthcare organiz ...
-
Senior Client Director
5 days ago
AKQA Inc San Francisco, United StatesSenior Client Director · At AKQA, we believe in the imaginative application of art and science to create beautiful ideas, products and services. With an entrepreneurial and collaborative approach, we design adaptive digital services and applications that capture the imagination, ...
-
Senior Director
5 days ago
Pattern Energy Group San Francisco, United StatesCompany Overview · Pattern Energy is a leading renewable energy company that develops, constructs, owns, and operates high-quality wind and solar generation, transmission, and energy storage facilities. Our mission is to transition the world to renewable energy through the susta ...
-
Senior Director, Partnerships
5 days ago
400 Athleta, Inc. San Francisco, United States Full timeAbout the Role · A critical member of the Athleta Marketing Leadership Team, the Senior Director of Partnerships leads wholistic partnership strategies, relationships and implementation for the brand. You will be charged with authoring a partnership strategy, taking into conside ...
-
Senior Director
1 week ago
Pattern Energy Group San Francisco, United StatesCompany Overview · Pattern Energy is a leading renewable energy company that develops, constructs, owns, and operates high-quality wind and solar generation, transmission, and energy storage facilities. Our mission is to transition the world to renewable energy through the susta ...
-
Senior Director/Executive Director
2 weeks ago
Alexandria Real Estate Equities, Inc San Francisco, United States**Senior Director/Executive Director - Laboratory Operations & Environmental, Health & Safety** · Location **San Francisco Bay Area, CA** · Job Function **Asset Services** · Employment Status **Regular, Full-Time, Exempt** · Apply Now ) · Alexandria Real Estate Equities, Inc. (NY ...
-
Senior Director, Patents
3 weeks ago
Dolby Laboratories San Francisco, United StatesJoin the leader in entertainment innovation and help us design the future. At Dolby, science meets art, and high tech means more than computer code. As a member of the Dolby team, you'll see and hear the results of your work everywhere, from movie theaters to smartphones. We cont ...
-
Senior Director/Executive Director
1 day ago
Alexandria Real Estate San Francisco, United StatesThe Senior Director - Laboratory Operations & Environmental, Health & Safety is responsible for developing and managing Environmental, Health & Safety (EH&S) programs to meet the company's strategic and tactical needs in coordination with members of the Asset Services and Facilit ...
-
Recruits Lab (We're hiring) San Francisco, United StatesAre you ready to pioneer groundbreaking precision medicine therapies in the field of oncology? Our client, a leading clinical-stage precision medicine oncology company, is seeking a visionary · Director/Senior Director of Pharmacokinetics and Clinical Pharmacology to join their ...
-
Senior Director of Accounting
1 week ago
Reneris San Francisco, United StatesA non-profit organization that for nearly 40 years has been at the leading edge of practical and innovative solutions to address the homelessness crisis in the San Francisco Bay Area and one of the regions largest, most comprehensive providers of essential services to individuals ...
-
Senior Director, Product
2 days ago
Lyft, Inc. San Francisco, United States0026 amp; Experience: 0026 /h 2ullistrong. Experience and Skills: Possess over 14 years of product management or relevant tech experience, with a strong foundation in Trust 0026 amp; Safety leadership preferred. Exhibit exceptional leadership, inter Director, Product Development, ...
-
Senior Director, Product Development
5 days ago
TATCHA San Francisco, United States Full timeWhat We Need · We are looking for a Senior DIrector, Product Development to join our dynamic, fast-paced team in San Francisco. · Reporting to the SVP, Global Innovation, we are seeking a Senior Director, Product Development, that will play a pivotal role in shaping the future of ...
-
Senior Client Director
6 days ago
AKQA San Francisco, United StatesAt AKQA, we believe in the imaginative application of art and science to create beautiful ideas, products and services. With an entrepreneurial and collaborative approach, we design adaptive digital services and applications that capture the imagination, delivering impressive ret ...
-
Senior Director, Sourcing
1 week ago
Jones Lange Lasalle, Inc. San Francisco, United StatesLead and grow a high-performing S&P team for a large technology client. Work directly with S&P leadership, Account leadership and clients to manage expectations and team deliverables. This includes accountability for effectively managing, mentoring, Director, Sourcing, Leadership ...
-
Senior Director Content Strategist
2 days ago
CIRCLE San Francisco, United StatesCircle is a financial technology company at the epicenter of the emerging internet of money, where value can finally travel like other digital data — globally, nearly instantly and less expensively than legacy settlement systems. This ground-breaking new internet layer opens up p ...
-
Director/Senior Director, Medicinal Chemistry
3 weeks ago
IDEAYA Biosciences, Inc. San Francisco, United StatesIDEAYA Biosciences (NASDAQ: IDYA) is a public, clinical-stage precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics. Our approach integrates ext ...
Senior Director - San Francisco, United States - Altos Labs
Description
Our Mission
Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.
Our Value
Our Single Altos Value:
Everyone Owns Achieving Our Inspiring Mission.
Diversity at Altos
We believe that diverse perspectives are foundational to scientific innovation and inquiry.
We are building a company where exceptional scientists and industry leaders from around the world work side by side to advance a shared mission.
At Altos, we are all accountable for sustaining a diverse and inclusive environment.
What You Will Contribute To Altos
An exciting opportunity is available for a talented Senior Director / Executive Director to join the Institute of Medicine (IOM) Development Sciences team at Altos Labs.
We are seeking very highly motivated, creative, and collaborative individuals who are passionate and dedicated to employing their expertise to restore cell health and resilience and reverse disease.
This position will be part of a multidisciplinary team within the IOM to develop novel therapeutic projects and pipelines at Altos.
The candidate will work in a highly dynamic and cross-functional environment that requires collaboration with the Institutes of Science and may span multiple therapeutic areas and therapeutic modalities.
The successful candidate will have strong scientific training, be adept with working with traditional and non-traditional therapeutic modalities, and a demonstrated track record of leading Toxicology groups in the biotechnology or pharmaceutical industry.
ResponsibilitiesQualifications
The salary range for Redwood City, CA:
For UK applicants, before submitting your application:
#635
What We Want You To Know
We are a culture of collaboration and scientific freedom, and we believe in the values of diversity, inclusion and belonging to inspire innovation.
Altos Labs provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).
Thank you for your interest in Altos Labs where we strive for a culture of scientific freedom, learning, and belonging.
Note:
Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee.
If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos.
Learn more about a common job scam at