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    Human Gene and Cell Therapy Staff Research Associate - Los Angeles, United States - UCLA Health

    UCLA Health
    UCLA Health Los Angeles, United States

    3 weeks ago

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    Description
    General Information

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    Work Location:
    Los Angeles, USA

    Onsite or Remote

    Fully On-Site

    Work Schedule

    Monday - Friday, 8:00am - 5:00pm

    Posted Date

    04/30/2024


    Salary Range:
    $ Hourly

    Employment Type


    • Staff: Career
    Duration

    Indefinite

    Job #

    15946

    Primary Duties and Responsibilities

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    Under the supervision of the Director of the Human Gene and Cell Therapy Facility (HGCTF), the HGCTF Manufacturing Associate (SRA) is responsible for the manufacturing of human gene and cell therapy products under Good Manufacturing Practices (GMP) and quality control testing of these products to ensure that the products meet the required quality per pre-established specifications.

    The purpose of the HGCTF is to manufacture clinical grade gene and cellular therapy products for novel patient treatments in clinical trials, and to perform scholarly research and development when appropriate.

    These objectives are to be met within the limits of resources available with an emphasis on cost effectiveness and innovation.


    In this role, you must have excellent tissue culture skills (human cell line and stem cell culture preferred) in order to be trained in GMP grade culture and formulation of various human cell types including peripheral blood mononuclear cells, T-cells, dendritic cells, multi potent stem cells such as mesenchymal stromal cells, pluripotent stem cells, such as human embryonic stem cells and induced pluripotent stem cells.

    Experience in quality control tests and assays such as endotoxin assay and mycoplasma testing is preferred.


    Annual Salary Range:
    $64, $103,718.76

    Job Qualifications

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    Required:

    • Bachelor of Science or Master of Science or Ph.
    D. Degree in Biology, Chemistry, or related field and/or a minimum of 2 years of tissue culture experience

    • Knowledge and practical experience in aseptic technique/tissue culture
    • Understanding of GMP requirements and regulations. Previous experience directly involved with federal regulations regarding GLP or GMP
    • Ability to wear protective clothing for extended periods of time including gowns, coveralls, gloves, masks, face shields, goggles, sleeves and head covers.
    • Ability to work flexible hours, various hours on short notice (including covering staff shortages, weekends and holidays); determine workload priorities for completion of job assignments in a timely manner to meet critical deadlines.
    • Work under regular exposure to zoonotic diseases, anesthetic agents, and cleaning chemicals
    • Strong interpersonal communication skills to effectively and diplomatically interact with physicians, staff, administration & sponsors.
    • Excellent record keeping skills and good documentation practices.
    • Demonstrated knowledge of FDA Good Laboratory Practice, Good Tissue Practice and Good Manufacturing Practice guidelines
    • Teamwork skills as well as the ability to prioritize and demonstrate critical thinking.
    • Demonstrated skill in prioritizing workflow to meet deadlines, often under pressure of conflicting demands, while maintaining accuracy and effectiveness of work.
    • Excellent English-writing skills to compose, proofread correspondence, and written reports for conciseness, clarity, appropriate grammar, correct spelling, and proper punctuation.
    • Demonstrated skills with personal computers, spreadsheets, databases, and word processing applications for the maintenance of records, analysis of data, and the preparation of reports.
    • Demonstrated skill in utilizing programs such as Word, Excel, and other database software.
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