- Independently plan, implement and troubleshoot binding assays, for example binding kinetics measurements (SPR, BLI)
- Analyze and present data and conclusions to colleagues from a variety of backgrounds
- Contribute to selection, planning and execution of a variety of laboratory assays for screening and characterization of candidate molecules
- Ensure seamless access to own and others' data for machine learning
- Collaborate on project planning, strategy and execution
- Help teach and mentor junior colleagues in your areas of expertise and experience
- Foster inter-disciplinary understanding of biophysical data among machine learning scientists
- CRO management as needed
- PhD with 5+ years OR MSc with 10+ years.
- Demonstrated relevant industry experience
- Proven expertise with biophysical binding assays for a variety of purposes (e.g., kinetics and steady-state binding affinity, epitope binning, competition assays, ADA assays, others) and developed in different formats appropriate for the experimental goals
- Experience with a variety of biochemical and interaction binding assays preferred (e.g., ELISA, AlphaLisa, TR-Fret, Bead-based, fluorescence, luminescence, flow cytometry)
- Experience with automation and liquid handling equipment for sample preparation and assay execution is strongly preferred
- Strong experience and understanding of antibody and biologics structure/function and discovery and optimization workflows
- Strong sense of initiative and interest in learning new technologies and addressing disease-relevant biology
- Enjoy collaborating with diverse scientists in both the wet-lab and dry-lab
- Enthusiasm for disrupting drug discovery with new approaches to data generation & curation to allow leveraging of machine learning technologies
-
Scientist/ Senior Scientist
1 week ago
Elektrofi Boston, United StatesABOUT ELEKTROFI · Elektrofi is a biopharmaceutical formulation technology company that is revolutionizing the delivery of biologic therapies by giving patients the ability to control how they want to receive and benefit from life-changing medicines. Our breakthrough ultra-high co ...
-
Scientist/Senior Scientist Immunology
1 week ago
Hillstar Bio Boston, United StatesAbout The Company · Hillstar Bio, is a precision immunology company that recently completed a sizable Series A financing with a syndicate of blue-chip investors. Our passionate team of drug developers is based in Boston's Seaport neighborhood. · Hillstar is advancing a portfolio ...
-
Senior Scientist
2 weeks ago
Integrated Resources, Inc ( IRI ) Boston, United StatesThe Research group is seeking a highly motivated Scientist to develop, optimize, execute bioanalytical assays to support company gene therapy programs. In this role, you will work closely with a team of scientists to advance AAV based gene therapies. · A successful candidate wil ...
-
Senior Clinical Scientist
1 week ago
Verve Therapeutics Inc Boston, United StatesThe Position · Verve is seeking an experienced Senior Clinical Scientist to join our team as we continue to advance gene editing medicines for cardiovascular disease into clinical development. In this position, you will be an integral part of the clinical development team support ...
-
Senior Data Scientist
3 weeks ago
Xyon Global Boston, United StatesSenior Data Scientist (Generative Healthcare AI) · Our Healthcare generative AI client is transforming the way healthcare works. We are looking for an exceptional Senior Data Scientist to join their team. As a member of the team, you will be at the forefront of generative AI in ...
-
Senior AI Scientist
4 weeks ago
Vizit Boston, United StatesVizit is looking for a talented Senior AI Scientist with Specialization in Video. · This role will be a member of our core team building and expanding upon Vizit's first-of-its-kind visual intelligence platform and image analysis services already in use by some of the biggest br ...
-
Senior Data Scientist
1 week ago
TechIntelli Solutions Inc Boston, United StatesTitle: Senior Data Scientist (Subject Matter Expert) Location: Boston, MA starting with 2 days working from Office and likely to get extended for all 5 days. Job Type: Contract Contract Type: W2 or C2C Pay rate: Open to discuss. · Visa: H1B, Senior Data Scientist with Subject Ma ...
-
Senior AI Scientist
3 weeks ago
Vizit Corp Inc. Boston, United StatesVizit is looking for a talented Senior AI Scientist with Specialization in Video. · This role will be a member of our core team building and expanding upon Vizit's first-of-its-kind visual intelligence platform and image analysis services already in use by some of the biggest br ...
-
Senior Data Scientist
3 weeks ago
Datadog Boston, United StatesSenior Data Scientist - Large Language Models / Generative AI · Our Data Science Large Language Models team uses advanced generative AI technologies to create powerful features within the Datadog application. Our focus lies in the fine-tuning, training, and serving of LLMs to po ...
-
Senior Data Scientist
3 weeks ago
Storm3 Boston, United StatesSenior Data Scientist · Publicly listed Biotech · Boston, USA (Hybrid) · Up to $180k Base + Significant Equity + Bonus · Interested in joining a company that are revolutionizing the AI Drug Discovery world? · They are building a world-class ML team to accelerate the use to comput ...
-
Senior Research Scientist
1 week ago
Vertex Pharmaceuticals, Inc Boston, United StatesJob Description · The Senior Research Scientist, Hematopoietic Stem Cell Biology is responsible for experimental productivity and emerging creativity and versatility. Designs and executes experiments for major research projects including the development of human stem cell models ...
-
Associate Scientist/Senior Associate Scientist
3 weeks ago
ascidian therapeutics Boston, United StatesAbout us: · Ascidian is redefining the treatment of disease by rewriting RNA. · Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from ...
-
Senior Research Scientist
3 weeks ago
Strativ Group Boston, United StatesA renowned company dedicated to advancements in the field of health is currently looking to add a skilled Senior Scientist to their team. The selected individual will contribute to the development of innovative machine learning models focusing on proprietary data for optimizing b ...
-
Senior Research Scientist
1 week ago
Partners Healthcare System Boston, United StatesGENERAL SUMMARY/OVERVIEW: · The position of Senior Research Scientist in the Boland lab will perform independently and efficiently work to support the Jackson 9 Translational Research Group's endeavors. This position assists Instructors and Principal Investigators as part of ongo ...
-
Senior Research Scientist
1 week ago
Mass Eye and Ear Boston, United StatesReserved for Pre-selected Candidate · * Perform original research. · * Mentor research trainees. · * Participate in teaching of graduate students as appropriate. · * Serve on committees at the Mass Eye and Ear and Harvard Medical School. · * Ph.D. · Massachusetts Eye and Ear is p ...
-
Senior Research Scientist
1 week ago
Partners Healthcare System Boston, United StatesReserved for Pre-selected Candidate · * Perform original research. · * Mentor research trainees. · * Participate in teaching of graduate students as appropriate. · * Serve on committees at the Mass Eye and Ear and Harvard Medical School. · * Ph.D. ...
-
Senior Data Scientist
4 weeks ago
Gardner Resources Consulting Boston, United StatesData Scientist · Responsibilities: · • Data Integration and Entity Resolution: Develop and implement methodologies to compare records from multiple data sources to identify whether they represent the same entity. Employ advanced techniques to handle data without common identifi ...
-
Senior Data Scientist
2 weeks ago
Circle Boston, United StatesCircle is a financial technology company at the epicenter of the emerging internet of money, where value can finally travel like other digital data — globally, nearly instantly and less expensively than legacy settlement systems. This ground-breaking new internet layer opens up p ...
-
Senior Data Scientist
3 weeks ago
Traivefinance Boston, United StatesWe are looking for a Data Scientist to analyze large amounts of raw information to find patterns that will help improve our company. We will rely on you to build data products to extract valuable business insights. · In this role,You will help our company analyze trends in comple ...
-
Senior Data Scientist
4 weeks ago
Red Hat Boston, United StatesAbout the job · Write open-source software that uses statistical models to predict system metrics that are used to optimize system performance. Write open-source software used for storing, retrieving and manipulating system data for analysis. · *Telecommuting permitted: work may ...
Senior Scientist - Boston, United States - Fable Therapeutics
2 weeks ago
Description
Senior Scientist - Antibody Discovery and Protein Interactions, Fable Therapeutics
About Us:
Fable Therapeutics (Fable) is a discovery-stage biotechnology company which develops purpose-built biologics designed to overcome therapeutic index limitations and channel therapeutic response where and when it matters.
Fable is powered by state-of-the-art structure and sequence-based protein language models. Founded by leading ML scientists and veteran biotech entrepreneurs together with top-tier venture capital firms, Fable has recently initiated its internal therapeutic pipeline and has enacted a growing list of pharma research collaborations.
Backed by a 2024 $40M Series A investment co-led by Versant Ventures and DCVC, Fable is positioned to lead in the purposeful integration of biology and computation to solve complex medical challenges. Fable's aspiration is to write the next chapter of what protein-based therapeutics can do.
Description:
We are seeking a talented individual to provide scientific & technical expertise in high-throughput biophysical antibody-antigen screening for drug discovery. In tight collaboration with our machine learning team, the expertise and data you provide will also be used to train state-of-the-art machine learning models. As an experienced technical expert in our growing group, you will have the chance to contribute to shaping the design of our screening and drug discovery set up, including contributing to critical decisions on infrastructure and automation.
The ideal candidate will have deep hands-on expertise independently planning, implementing and troubleshooting biophysical binding assays and related instrumentation (e.g., Surface Plasmon Resonance/SPR, BLI, Carterra, Biacore, Octet, NanoTemper). Broad experience in other types of biochemical and interaction binding assays preferred (e.g., ELISA, AlphaLisa, TR-Fret, Bead-based, fluorescence, luminescence, flow cytometry). As an enthusiastic team member, you will have the chance to learn and collaborate with other bench scientists and with machine learning scientists (dry-lab) as part of our multi-disciplinary approach to discover and develop precision engineered drug candidates.
This is an on-site role. Flexible working hours to promote a balance between productivity and wellness can be accommodated with manager approval
Responsibilities:
About You:
At Fable Therapeutics, we know that our people drive our success. We are an equal opportunity employer and we value diversity and inclusion. Fable Therapeutics provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Fable Therapeutics does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law.
For accommodations during the interview process please email