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    Research Fellow BWH Neurology - Brookline, United States - Brigham and Women's Hospital

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    Description
    The Principal Investigators Ulf Dettmer and Nagendran Ramalingam in the Ann Romney Center

    for Neurologic Diseases, Brigham & Women's Hospital, and Harvard Medical School jointly invite

    applications from recent graduates for two fully NIH-funded postdoc positions to study the

    pathophysiology of alpha-synuclein. The research projects will focus on a) understanding the

    physiology of Ser129 phosphorylated alpha-synuclein "pS129" in vivo and b) understanding the

    role of pS129 on pathological spreading of alpha-synuclein aggregation in vivo. The ideal

    candidate with strong animal work experience will work with novel knock-in mouse models that

    have been generated for these projects. Both projects are relevant for Parkinson's disease and

    Lewy body dementia.

    The projects are built upon two research papers:

    00444-w and

    Candidates must have extensive experience working with mice. Prior experience in survival

    surgery or electrophysiology is highly desirable. Only candidates with demonstrated expertise and

    publications in molecular biology, biochemistry, imaging, and animal husbandry should apply.

    A competitive salary will be provided.

    Requirements


    • A Ph.
    D. in neuroscience, biochemistry, or a related biological field.

    • Excellent track record of publications.
    • Extensive experience with mouse studies, including behavioral analysis, listed in detail in
    the CV.


    • Experience in molecular biology, imaging, and biochemistry, listed in detail in the CV.
    • Cell culture (primary neurons) experience preferred, listed in detail in the CV.
    • Self-motivated and driven individuals able to work both independently and in a team
    environment.


    • Excellent oral and written communication skills in English.
    • Minimum three-year commitment.
    As there may be numerous applicants, we apologize in advance for not replying to every email

    while we recruit candidates with all of the above qualifications.

    To apply, interested applicants should send a CV with the contact information of 3 references and

    a cover letter detailing research experience/accomplishments with a potential start date directly

    to


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