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    Director, Materials Engineering - New Brunswick, United States - Bristol-Myers Squibb

    Bristol-Myers Squibb
    Bristol-Myers Squibb New Brunswick, United States

    3 weeks ago

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    Description
    Working with UsChallenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department.

    From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

    Youll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity.

    Take your career farther than you thought possible.
    Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment.

    We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.


    Read more:
    Description:

    Material Science & Engineering (MSE) in Drug Product Development (DPD) plays an integral role in materials selection and building robust form and powder property control strategies of the active pharmaceutical ingredient (API) in the drug product.

    The Director of the Materials Engineering & Crystallization (MEC) group in the Material Science & Engineering will be responsible for building, leading, and developing a high-performing team accountable for material form/polymorph screening, morphology/powder property screening, unit operations in API process development including crystallization, isolation and drying, and drug product intermediate (DPI) development such as spray drying and coprocessing.

    Accountability spans the small -molecule portfolio from pre-clinical/FIH through life cycle management.

    To achieve MSE goals the MEC director will collaborate closely with interfaces at discovery, drug substance, analytical, drug product and commercial manufacturing to align on material strategy and ensure that key form and powder property strategies are embedded in the API and/or DPI processes.

    The successful candidate will have a well-established track record of successful leadership, stakeholder management, development of people, strong technical background covering the multi-disciplinary areas of the function and be responsible for helping shape and execute MSE vision and objectives.


    Key job responsibilities:


    Responsible for the direct management of multiple teams of material scientists and leaders to deliver on material strategy including form screening and crystallization, isolation, and drying process development of APIs in the small molecule portfolio spanning GT2 to NDA approval.

    Ensuring throughout the process that compliance & EHS regulations and company policies & procedures are adhered to.

    Collaborate closely with stakeholder groups to ensure successful crystallization isolation and scale-up at internal and external clinical and commercial manufacturing sites, including generation of material knowledge and understanding to support material robustness targets.

    Supports registration, validation, and launch and life cycle management.

    Provide guidance, as required, for material teams to ensure high performance and close alignment with the goals of BMS R&ED, GPS, and Commercial.

    Implement new technologies, systems, and ways of working to enhance productivity & position the organization to successfully deliver in the evolving environment to help the organization realize its Quantum Leap aspirations.

    Grow and develop talent within the organization.

    Provide scientific and strategic leadership oversight to maximize organizational impact and seek out challenging developmental experiences for scientists to learn and grow.

    Partner closely with stakeholders and proactively seek and identify portfolio and systemic needs/opportunities, align on priorities, and jointly develop and operationalize integrated strategies.

    Build and foster strong relationships with key stakeholder functions.

    Ensure strategic alignment and close partnership with other functions within DPD/PD as well as with other organizations to develop and execute strategy.

    Key interfaces include DPD functions (EB, OPD, DDPS, IT&E), PD functions (PSI, CSO, PDO and ASO), and GRS-CMC.Manages external partners responsible for form screening and powder property screening.

    As a key member of the MSE leadership team, help shape, develop, and execute the overall strategy for the group, interface with key stakeholders and ensure the group is successfully delivering on its overall mission.

    Represent, as appropriate, the group at governance meetings and on DPD enterprise teams.
    Trains matrix team leaders responsible for building end to end materials strategies for small molecule portfolio projects.
    Organizes and leads best practices for API and DPI process development.


    Required Qualifications and Experience:
    B.S./M.S./Ph.
    D.

    in chemical engineering, materials engineering, or related discipline with 12 years of pharmaceutical and/or chemical industry experience and a solid record of roles with increasing responsibilityStrong technical expertise (pharmaceutics/formulation/engineering) that can be used to guide project team material strategy from discovery through pivotal/commercialization for small molecules.

    Demonstrated problem-solving skills with a strong background in the theory and practice of crystallization, solid form screening, process development, isolation, and drying techniques.

    Experience with small or complex molecule particle engineering such spray drying, co-crystals, peptide crystallization and/or other novel isolation techniques will be preferred.

    Demonstrated ability to contribute to and shape and drive the execution of the strategic vision of the MSE organization.

    Demonstrated managerial and leadership skills in leading group of scientists and engineers, and to effectively work with multifunctional organizations and stakeholders.

    Previous success working effectively in a multidisciplinary, highly matrixed environment and in building high-performing teams.
    Demonstrated ability to effectively coach/guide/mentor & drive accountability. Demonstrated enterprise mindset in creating an environment/culture for developing talent in the overall organization.
    Demonstrated track record of building and fostering strong partnerships with stakeholders and operating with an enterprise mindset. Skilled in negotiation and influencing (internal/external) and is an effective change agent.
    Excellent decision-making, written and verbal communication skills.

    If you come across a role that intrigues you but doesnt perfectly line up with your resume, we encourage you to apply anyway.

    You could be one step away from work that will transform your life and career.

    Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as Transforming patients lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary.

    Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

    On-site ProtocolPhysical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

    BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles.

    Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer.

    If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to Visit to access our complete Equal Employment Opportunity statement.

    BMS cares about your well-being and the well-being of our staff, customers, patients, and communities.

    As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

    BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

    Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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