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Research Associate
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Research Associate
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Research Associate
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Research Associate I
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Research Associate WPIC
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Research Associate WPIC
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Research Associate WPIC
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Research Associate II
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Research Associate - Pittsburgh, United States - Novasenta
Description
This role will support the Assay Development team and will perform both In-Vitro and In-Vivo duties.
Responsibilities:
· Reports to assigned leader to ensure meeting the goals of Novasenta and pursuing the most promising targets within the tumor microenvironment for the development of therapeutics.
· Conducts routine and non-routine lab procedures and assays for molecular, cellular, and metabolic characterization of relevant samples from mouse models of cancer and human clinical cancer tissue.
· This includes the conduct of relevant exploratory experiments and control experiments, applying basic scientific principles.
· As needed, supports the development and validation of new technologies for molecular, cellular and metabolic characterization of samples.
· Supports the development of biological, immunological assays to investigate mechanisms of immune-mediated effects of novel identified targets.
· Contributes to the profiling and validation of novel druggable immunotherapy targets.
· Documents and maintains a detailed and precise record of work performed.
· Performs lab managerial, which includes ordering supplies and maintaining inventory, ensuring safety, service and maintain laboratory instruments of the lab,etc
· Actively participates in the scientific dialogue of the group and proactively collaborates with colleagues
· Performs all other duties as assigned.
Qualifications:
Master's Degree from an accredited institution or bachelor's degree from an accredited institution and 1 year lab experience either in industry or academic lab required.
Prior biopharma industry or commercial research experience desired experience with several of the following relevant techniques:
· Mammalian cell culture
· Flow cytometry and cell sorting
· Molecular biology techniques (e.g., PCR, development of genetic constructs, cloning, etc.)
· NGS (WGS, WES or RNAseq, including preparation of genomic libraries)
· CRISPR or other advanced genetic editing techniques
· Processing and characterization of fresh human tumor samples
· Cell-based metabolic assays
Ability to propose new experimental designs, plan and conduct laboratory experiments, and evaluate and interpret data.
Fundamental understanding of the process of discovery and development of immunology-based therapeutic targets and possible novel therapeutic concepts
Experience in immuno-oncology-related animal studies.
The role requires critical thinking e.g. by proposing and implementing novel experimental approaches and concepts contributing to cancer immunology and immune therapy research goals.
The ideal candidate is product and goal oriented, focused on a career in biotech. They are highly efficient and organized and have a demonstrated ability to adhere to and follow defined timelines, milestone, and objectives.
Experience in working under GLP standards and ensuring safety compliance under BSL-2.
Experience with laboratory information system (LIMS) is a plus.
Good verbal and written communication skills and the ability to interpret, summarize, and present results in a clear, concise, accurate manner.