- Identify and develop vaccine candidates through preclinical efforts and support their advancement to clinical development.
- Design, direct, interpret, and communicate experiments and strategy to evaluate antigens and select lead candidates for progression to early clinical development.
- Translate strategic vaccine pipeline and program goals into operational plans within define timeline and budget.
- Manage and lead a team of scientists and associates, as direct reports, and work with research and cross-functional early development colleagues in delivering the functional and company objectives.
- Responsible for delivering critical-path activities to advance preclinical programs.
- Contribute broadly to the work of the group, serve as a senior leader within the preclinical team and provide management of laboratory activities and fulfillment of compliance obligations.
- Review and provide expert input into internal study plans, study reports, technical documents, patent applications, regulatory submissions (INDs, IBs), scientific papers and other communications for existing and new programs.
- Ph.
- 10+ years industry experience in pharmaceutical/biotech and contribution record in viral and bacterial vaccines discovery and development with 4+ years of supervisory experience.
- Demonstrated knowledge and experience of recombinant vaccine antigen expression, purification, analytical characterization and advancing vaccine candidates through preclinical evaluation into development.
- Experience with laboratory management and environmental and safety compliance
- Experience of management of direct reports and organizational skills working in a cross-functional/matrix environment.
- Experience in adjuvants and vaccine formulation is desirable.
- Strong verbal/written communication and organizational skills.
- Ability to work independently in a fast-paced environment.
- Manual dexterity required to operate office equipment (i.e. computers, phones, etc.).
- Location: Seattle, WA
- Must be eligible to work in the USA
- To reduce the presence and severity of COVID-19 cases in the workplace and in our communities, Icosavax requires all newly hired employees to be fully vaccinated against COVID-19 before commencing employment, subject to reasonable accommodation and other requirements of applicable federal, state and local law.
-
Postdoctoral Fellow
2 weeks ago
Seattle Children's Hospital Seattle, United StatesResponsibilities · The malaria research laboratory of Dr. Stefan Kappe ) at the Center for Global Infectious Disease Research (CGIDR), Seattle Children's Research Institute (SCRI), is recruiting a Postdoctoral Scientist to identify and characterize novel transmission blocking vac ...
-
Research Technician II
2 weeks ago
Fred Hutchinson Cancer Research Center Seattle, United StatesOverview · Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center i ...
-
Medical Science Liaison
2 weeks ago
Syneos Health, Inc Seattle, United States· You are a listener, an educator and a gifted cultivator of new and exciting opportunities grounded in science. · In this role, you will confer with internal stakeholders and build new collaborative relationships with medical and scientific leaders, policymakers, and advocates. ...
-
Post-Doctoral Research Fellow
2 weeks ago
Fred Hutchinson Cancer Research Center Seattle, United StatesOverview · Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center i ...
-
Post-Doctoral Research Fellow
2 weeks ago
Fred Hutchinson Cancer Research Center Seattle, United StatesOverview · Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center i ...
-
Postdoctoral Fellow
2 weeks ago
Seattle Children's Hospital Seattle, United StatesResponsibilities · There is strong evidence that underrepresentation is an important problem that the health research enterprise must address (see Women, Minorities and Persons With Disabilities in Science and Engineering). Fostering diversity by addressing underrepresentation in ...
-
Seattle Pacific University Seattle, United StatesAbout Seattle Pacific University: · Founded in 1891, Seattle Pacific University has a long and distinguished history in Christian higher education. Located just minutes from downtown Seattle, SPU seeks to be a premier Christian University fully committed to engaging the culture a ...
-
Staff Scientist
2 weeks ago
Fred Hutchinson Cancer Research Center Seattle, United StatesOverview · Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center i ...
-
Senior Program Officer, Malaria
3 weeks ago
Bill & Melinda Gates Foundation Seattle, United States Full timeThe Foundation · We are the largest nonprofit fighting poverty, disease, and inequity around the world. Founded on a simple premise: people everywhere, regardless of identity or circumstances, should have the chance to live healthy, productive lives. We believe our employees shou ...
-
Research Associate II
2 weeks ago
Seattle Children's Hospital Seattle, United StatesResponsibilities · Research Associate II · The Coler Lab is a dynamic team of translational researchers focused on understanding the complex pathogen-host interactions that control the outcome of infection and immunity. The laboratory is dedicated to characterizing vaccines and h ...
-
Pediatric Immunization Specialist, Washington
2 weeks ago
GlaxoSmithKline Seattle, United StatesSite Name: USA - Washington - Seattle · Posted Date: May · For more than 140 years, GSK has pioneered novel research methods and technologies to help protect people from infectious diseases. Our vaccines portfolio of more than 20 marketed vaccines is the broadest in the industry ...
-
Senior Program Officer, New Vaccine Introduction
3 weeks ago
Bill & Melinda Gates Foundation Seattle, United StatesThe Foundation · We are the largest nonprofit fighting poverty, disease, and inequity around the world. Founded on a simple premise: people everywhere, regardless of identity or circumstances, should have the chance to live healthy, productive lives. We believe our employees shou ...
-
Director, Translational CMC
2 weeks ago
Icosavax Seattle, United StatesSUMMARY: Icosavax, Inc., a member of the AstraZeneca Group (LSE/STO/Nasdaq: AZN), is a biopharmaceutical company focused on developing differentiated, high-potential vaccines using an innovative, protein virus-like particle (VLP) platform. Icosavax's VLP platform technology is de ...
-
Lead AI/ML Engineering
2 weeks ago
GlaxoSmithKline Seattle, United StatesSite Name: Seattle Sixth Ave · Posted Date: May · At GSK we see a world in which advanced applications of artificial intelligence and machine learning (AI/ML) will allow us to develop new medicines and vaccines with greater speed and efficacy. GSK is a unique company with world ...
-
Research Coordinator
2 days ago
University of Washington Seattle, United StatesAs a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills and dedication to build stronger minds and a healthier world. · UW faculty and staff also ...
-
Clinical Research Coordinator I
2 weeks ago
Fred Hutchinson Cancer Research Center Seattle, United StatesOverview · Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center i ...
-
Research Technician I/II
2 weeks ago
Fred Hutchinson Cancer Research Center Seattle, United StatesOverview · Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center i ...
-
Lab Aide
4 weeks ago
Fred Hutchinson Cancer Research Center Seattle, United StatesOverview · Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center i ...
-
Research Project Coordinator
2 weeks ago
University of Washington Seattle, United StatesAs a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills and dedication to build stronger minds and a healthier world. · UW faculty and staff also ...
-
Lab Aide
2 weeks ago
Fred Hutchinson Cancer Research Center Seattle, United StatesOverview · Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center i ...
Director, Vaccines Research - Seattle, United States - Icosavax
4 weeks ago
Description
SUMMARY:
Icosavax, Inc.
, a member of the AstraZeneca Group (LSE/STO/Nasdaq:
AZN), is a biopharmaceutical company focused on developing differentiated, high-potential vaccines using an innovative, protein virus-like particle (VLP) platform.
Icosavax's VLP platform technology is designed to enable multivalent, particle-based display of complex viral antigens, which it believes will induce broad, robust, and durable protection against the specific viruses targeted.
Icosavax's pipeline includes vaccine candidates targeting respiratory syncytial virus (RSV) and human metapneumovirus (hMPV).Based in Seattle, Icosavax was formed in 2017 to advance the breakthrough VLP technology with the goal to discover, develop, and commercialize vaccines against infectious diseases.
In 2024, AstraZeneca acquired Icosavax, Inc.AstraZeneca is a global, science-led biopharmaceutical company that focuses on the discovery, development, and commercialization of prescription medicines in Oncology, Rare Diseases, and BioPharmaceuticals, including Cardiovascular, Renal & Metabolism, and Respiratory & Immunology.
The Icosavax preclinical group, based in Seattle, WA is seeking a Director, Vaccines Research with a strong background in vaccine research, antigen discovery and development, and protein biochemistry with prior experience in protein expression, purification and characterization to help progress our vaccine candidates through preclinical pipeline into early clinical development.
This individual will manage a team of scientists and associates in vaccine antigen identification, screening, and final selection of the lead vaccine candidate through a series of in vitro and in vivo studies and support advancement of the selected candidate to clinical development.
The Director, Vaccines Research will report to SVP, Preclinical and will collaborate with internal and external teams on various R&D projects and serve as a leader and scientific expert and a senior leader within the preclinical team.
This is an impactful, high-profile and visible role and requires an individual with outstanding scientific, communication and team and project leadership skills as well as the ability to build positive relationships with expert functions within the organization.
JOB DUTIES:
EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
PHYSICAL DEMANDS:
OTHER:
The salary range for this position is $190,000 - $230,000 per year; the base salary will be determined based on knowledge, skills, education, and experience relevant to the role.
Employees are offered health insurance (medical, dental, vision), health savings account with company contribution, flexible spending account, life insurance, short- and long-term disability, 401(K) plan with company contribution, vacation, sick and safe time, company holidays and floating holidays.
