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Research Technician III
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Immunopathology Technician III
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Charles River Laboratories Durham, United StatesImmunopathology Technician III · Req ID #: 222611 · Location: · Durham, NC, US, 27703 · For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a signifi ...
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Immunopathology Technician III - Durham, United States - Charles River Laboratories, Inc.
Description
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
Job Summary
Generate and record data in the performance of basic to complex tasks associated with or in support of immunopathology laboratory procedures. Responsible for handling and processing samples, and performing accurate data collection and reporting. Provide technical guidance and serve as a mentor to less experienced staff.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
• Perform basic to complex tasks associated with or in support of immunopathology laboratory procedures and collect and record/document research data in compliance with Good Laboratory Practices (GLPs), Standard Operating Procedures (SOPs), study protocols and company policies/practices.
• Handle unfixed human and animal tissues (e.g. preparation of frozen OCT-embedded tissue blocks and cryotomy).
• Perform dilution calculations, moderately complex chemistry, and problem solving.
• Perform troubleshooting and methods design with study pathologists.
• Ensure the use of appropriate positive/negative tissue controls; fixations, staining procedures/techniques, and solution preparation.
• Input, print and edit computer entries (e.g., laboratory data).
• Receive samples and complete tracking documentation.
• Review documentation of functions performed as part of quality control requirements.
• Perform study preparation activities including sample labeling, equipment verifications, identifying supply needs, and working with study personnel to develop and implement study specific procedures (as appropriate).
• Perform more difficult/strenuous immunopathology tasks (e.g. high volume staining, simultaneous staining of different procedures, high volume cryotomy, precomplexes, and/or cross-reactivity staining, etc.)
• Work with hazardous materials in biosafety cabinet as needed (e.g. immunotoxin conjugated test materials)
• May assist with reviewing and updating processes and SOPs as assigned.
• May participate in sponsor representative interactions under the direct supervision of senior scientific staff or management.
• May develop new techniques or procedures to expand the capabilities of the department.
• Provide training to new employees as needed.
• May perform and document equipment maintenance and qualification as needed.
• May provide supervision of laboratory staff as needed.
• Maintain clean work areas.
• Perform all other related duties as assigned.
Job Qualifications
• Education: Bachelor's degree (B.A. / B.S) or equivalent in relevant experience in laboratory science or related discipline required.
• Experience: Four or more year's related experience in biology, chemistry/pharmacy, or similar lab environment GLP experience required. Must have demonstrated full knowledge of competencies at the previous level.
• An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
• Certification/Licensure: None
• Other: Knowledge of GLPs and other federal regulations and guidelines. Attention to detail and accuracy a must. Must be able to communicate effectively with management, coworkers and sponsors. Basic Microsoft Office skills are required. Understanding of mathematical concepts required.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.
Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to [email protected]. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
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