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    Medical Director - Emeryville, CA, United States - Kyverna Therapeutics

    Kyverna Therapeutics
    Kyverna Therapeutics Emeryville, CA, United States

    2 weeks ago

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    Description

    Kyverna Therapeutics is a clinical-stage cell therapy company with the mission of engineering a new class of therapies for autoimmune diseases.

    The Kyverna therapeutic platform combines advanced T cell engineering and synthetic biology technologies to suppress and eliminate the autoreactive immune cells at the origin of autoimmune and inflammatory diseases.

    Be at the forefront of cell therapy innovation by joining scientists, industry veterans and healthcare visionaries and help transform how autoimmune diseases are treated.

    Kyverna is seeking a highly motivated Medical Director or Senior Medical Director with significant experience in clinical development to join our team developing novel and innovative engineered T cell-based therapies for autoimmune diseases.

    The ideal candidate will contribute to our goals of navigating what's next in synthetic biology, immunology and cell engineering while living our core values:
    Reporting to the Chief Medical Officer

    Serve as the medical lead for CAR T-cell therapy clinical trials in multiple autoimmune disease indications, in partnership with internal and external cross-functional teams.

    Support, as the clinical representative, the transition of preclinical projects to clinical development.
    As the clinical trial study physician, be responsible for clinical deliverables and activities, including:
    Medical monitoring of clinical trials
    Medical review, analysis, and interpretation of safety, efficacy, and PK and biomarker data
    Development of clinical trial documents including protocols, ICFs, clinical development plans, and publications.

    Lead the development of clinical sections of regulatory documents including the IB, safety updates, clinical study reports, and responses to Health Authorities.

    MD (or ex-US equivalent) or MD-PhD degree required. Advanced degree or research experience in immunology preferred.
    ~5+ years of clinical research experience with 2+ years of industry experience in clinical development involved in the design and execution of clinical trials. Experience in early clinical development and translational medicine preferred.
    ~ Specialty training in rheumatology and/or industry experience in clinical development of therapeutics in autoimmune diseases.
    ~ Proven ability to interpret, discuss and present efficacy and safety data
    ~ Working knowledge of GCP/ICH, clinical trial design, clinical development processes, and regulatory requirements.
    ~ Strong ability to communicate and establish effective working relationship with investigators, collaborators, scientific advisors, CROs, and corporate partners.


    This salary range is an estimate of what we reasonably expect to pay for this posted position, and the actual salary may vary based on various factors, including without limitation individual education, relevant experience, tenure, skills and abilities, geographic location, as well as internal equity and alignment with market data.

    This position is also eligible for bonus, benefits, and participation in Company's stock option plan

    Kyverna is committed to the principle of equal employment opportunity for all employees and does not discriminate on the basis of race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other legally protected status.

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