- You will be responsible for designing, planning, and executing animal experiments to support the development of LNP delivery with various cargoes crossing BBB via systemic injection, or delivery of therapeutic cargos in the desired regions or cell types through local injections such as ICV.
- He or she will be working with an internal team and external CROs for downstream analysis, including biomedical imaging, pathology, and bioanalytical analysis.
- Studies will include small animal brain characterization, biodistribution, disease model development, drug efficacy, and toxicology-like studies in neurology.
- This position will provide an opportunity for growth and exposure to cutting-edge research projects.
- Ph.
- Have hands-on experience working with brain tissue dissection, histology (IF, FISH), imaging, and protein characterization. Working knowledge of organ physiology and cell biology in the mammalian CNS.
- The qualified candidate should have considerable experience in systematic or local injection, brain and tissue collection, molecular analysis, and downstream analysis (RT-qPCR, western blot, ELISA, bDNA quantification and IHC).
- Ability to work in the lab independently and in collaborative efforts with internal in vitro/ex vivo and in vivo groups, as well as external contractors as necessary (CROs, academics).
- Well-organized, detail-oriented, and results-driven with multi-tasking skills
- Applicants must be authorized to work in the U.S.
-
Cambridge Health Alliance Somerville, United StatesCHA has a vibrant academic community with strong education, training and research programs. We are proud to have 700 providers on the faculty at Harvard or Tufts University School of Medicine. The Research Scientist will be responsible for developing his/her own independent resea ...
-
AbbVie Cambridge, United StatesCompany Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas ...
-
AbbVie, Inc Cambridge, United StatesCompany Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas ...
-
BioSpace Cambridge, United StatesJob Details · Company Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key the ...
-
AbbVie Cambridge, United StatesJob Description · Job DescriptionCompany Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives acr ...
-
AbbVie Cambridge, United States Full time· Company Description · AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic ar ...
-
Associate Scientist
2 weeks ago
Lilly Cambridge, United StatesAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve th ...
-
Scientist - in Vivo Surgical Associate
2 weeks ago
Lilly Cambridge, United StatesAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve th ...
-
Lab Technician, I
2 weeks ago
Cerevel Therapeutics, LLC Boston, United StatesBoston, MA · **Company Overview**: · Cerevel Therapeutics is dedicated to unraveling the mysteries of the brain to treat neuroscience diseases. We are tackling neuroscience diseases with a differentiated approach that combines expertise in neurocircuitry with a focus on receptor ...
-
Research Specialist Bwh Neurology
1 week ago
Brigham & Women's Hospital(BWH) Boston, United States**Research Specialist BWH Neurology** · 2. As part of his job, George would be expected to work with and co-supervise with myself 1 postdoctoral fellow and one graduate student, Andriani Rina, helping to guide them through the appropriate formulation of the circuit analysis that ...
-
Research Technician
1 week ago
Massachusetts General Hospital(MGH) Boston, United States**Research Technician** · **GENERAL SUMMARY/ OVERVIEW STATEMENT**: · **PRINCIPAL DUTIES AND RESPONSIBILITIES**: · - Primary responsibility for management of knockout and transgenic mouse colonies · - Isolation of genomic DNA from tail biopsies · - Genotyping by PCR analysis · - A ...
-
AbbVie Boston, United States**Company Description** · The Manager of Statistical Programming is a strategic role which guides a team of Statistical Programmers in the research and development of new pharmaceutical products. This role is directly responsible for leading the statistical programming activities ...
-
Research Assistant I Psychiatry
1 day ago
Mass General Brigham Somerville, United StatesThe Psychiatry Neuroimaging Laboratory is looking to hire a qualified candidate for the position of Research Assistant. The laboratory is part of the Department of Psychiatry at Brigham and Women'sl Hospital. The main mission of this laboratory is to Research, Psychiatry, Assista ...
-
Harvard University Cambridge, United StatesDetails · Title Postdoctoral Fellow Position in The Neural Basis of Aggression · School Faculty of Arts and Sciences · Department/Area Human Evolutionary Biology · Position Description · The Department of Human Evolutionary Biology at Harvard University invites applications ...
-
Associate Scientist, Discovery-Immunology
2 weeks ago
Johnson & Johnson Cambridge, United StatesThe Innovative Medicine division of Johnson and Johnson is recruiting for (2) Associate Scientists, Discovery Immunology located in Cambridge, MA. · At Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing ...
-
Clinical Scientist III
6 days ago
Randstad Life Sciences US Cambridge, United StatesThis position is anticipated to open within the next couple of months** · We are seeking a PhD, PharmD, or MD Clinical Scientist for our Global Pharmaceutical Client in Cambridge, MA. Very attractive pay rate · This role will support a director in the medical scientific contribu ...
-
Research Assistant I Psychiatry
3 days ago
Brigham & Women's Hospital(BWH) Somerville, United StatesGENERAL SUMMARY/ OVERVIEW STATEMENT: The Psychiatry Neuroimaging Laboratory is looking to hire a qualified candidate for the position of Research Assistant. The laboratory is part of the Department of Psychiatry at Brigham and Women'sl Hospital. The main mission of this laborator ...
-
Research Associate
3 days ago
LifeCanvas Technologies Cambridge, United StatesLifeCanvas Technologies is an MIT spinoff venture aiming to revolutionize the way we see and study biological systems to elevate human health. LifeCanvas offers cutting-edge technologies and end-to-end solutions that enable holistic molecular imaging of biological systems to acce ...
-
Research And Development Scientist
1 week ago
GForce Life Sciences Cambridge, United StatesAssociate Scientist · Duration: 6-month contract · Location: Cambridge, MA · Description: · We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics efforts within our department of Biotherapeutic and Medicinal Scien ...
-
Research Assistant I Psychiatry
1 day ago
Brigham & Women's Hospital(BWH) Somerville, United StatesGENERAL SUMMARY/ OVERVIEW STATEMENT: · The Psychiatry Neuroimaging Laboratory is looking to hire a qualified candidate for the position of Research Assistant. The laboratory is part of the Department of Psychiatry at Brigham and Women'sl Hospital. The main mission of this labora ...
Research Scientist, Neuroscience - Woburn, United States - Hopewell Therapeutics
1 week ago
Description
Hopewell Therapeutics is discovering, synthesizing, and developing the next generation of tissue-targeted lipid nanoparticles (ttLNPs) to bring genomic medicines to patients.
We're pursuing opportunities to redefine the non-viral delivery space for novel genomic medicines by designing systemically administered LNPs to specifically target extrahepatic tissues and cells throughout the body.
Hopewell has built a robust intellectual property portfolio with an expansive library of ionizable lipids and has established partnerships with several industry-leading companies.
We're developing our own internal pipeline, initially targeting diseases of the lung, while concurrently exploring the potential of our ttLNP platform for patients with unmet needs in oncology, infectious diseases, rare genetic diseases, and neurological disorders.
Position OverviewHopewell is seeking a full-time postdoctoral research scientist in Neuroscience or Neurobiology.
This individual will work with the lipid chemistry and LNP process development team to develop LNP delivery technology encapsulating therapeutic cargoes to treat various neurodegenerative diseases.
The individual is expected to work well in a fast-paced, collaborative cross-disciplinary start-up biotech environment.Primary Responsibilities
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or any other characteristic protected by law.
In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification document form upon hire.
Please submit your resume to
&v=024){kind=logo}
&v=024){kind=logo}
