Associate Scientist - California, United States - Insmed Incorporated

Insmed Incorporated California, United States

3 weeks ago

Full time

Description

Company Description

Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.

Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.

Recognitions

Named Science's Top Employer in 2021, 2022, and 2023

Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That's why we were named the No. 1 company to work for in the biopharma industry in Science's Top Employers Survey for two years in a row.

A Certified Great Place to Work

We believe our company is truly special, and our employees agree. In July 2023, we became Great Place to Work-certified in the U.S. for the third year in a row. We are also honored to have been listed on the Best Workplaces in BiopharmaTM, Best Workplaces in New YorkTM, and Best Workplaces for MillennialsTM lists.

Overview

Insmed is seeking a scientist with significant experience with mouse vivarium experiment management and execution. This scientist will be responsible for execution of preclinical mouse models of neuro and muscular genetic diseases with research preparations of therapeutic constructs, including mouse genotyping, dosing, functional analysis, and tissue collection. Additionally, the scientist will document his/her methods and studies, and participate in the technical transfer of assays to third party contractors. Depending on experience, the scientist will work with current team members to develop new animal models. Beyond vivarium expertise, this position will also be responsible for histology techniques related to the animal studies, including tissue collection, sectioning, and staining. Familiarity with the use of a cryostat, histological techniques, and immunostaining techniques are required. Experience with behavioral tests and electrophysiological readouts are desirable.

Responsibilities

Additional representative responsibilities will include, but not necessarily be limited to, the following:
• Handle mouse genetic models of disease, including breeding pairs, ID-tagging, injections (ICV, facial vein and tail vein), weighing
• Behavioral tests and physiological assessments

• Tissue collection from mice on study and appropriate handling and storage of tissue

• Use of cryostat to generate slides for histology

• Staining protocols (eg. H&E) as well as immunohistochemistry

• Documentation of results in appropriate formats provided by supervisor

Qualifications

Master's degree in biology or relevant discipline with a minimum of 3-4 years of relevant experience or Bachelor's degree in biology or relevant discipline with a minimum of 5 years of relevant experience.

At least two years in vivo experience in mouse handling, tagging and weaning, demonstrating proficiency and ability to work with limited supervision.

In vivo expertise in colony management, breeding and weighing. Daily colony maintenance for multiple mouse models is required.

Experience with in vivo injections including p1 ICV and facial vein injections and p28 tail veins injections demonstrating proficiency.

Histology proficiency required for sectioning and staining various in vivo samples for biodistribution.

Analyze functionality and survival data for ongoing experiments.

Development of survival study graphs and survival curves.

Organization of experiments and protocol writeups for developing R&D experiments.

Knowledge of Good Documentation Practices and Good Laboratory Practices (GxP) is a plus.

Proficiency in following protocols and working in a fast-paced, high-energy environment.

Willingness to learn new techniques and train other laboratory staff in technical matters.

Entrepreneurial spirit, with strong willingness to take on new challenges required to bring novel medicines to the clinic.

Strict adherence to environmental, health, and safety guidelines. #LI-KM #LI-Onsite

Travel Requirements

Minimal

Salary Range

Insmed takes into consideration a combination of candidate's education, training, and experience as well as the position's scope and complexity, the discretion and latitude required in the role, and external market and internal value when determining a salary level for potential new employees.

The base salary range for this job is from $86,000.00 to $115,333.00 per year

Compensation & Benefits

We're committed to investing in every team member's total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including:

Flexible approach to where and how we work

Competitive compensation package including bonus.

Stock options and RSU awards

Employee stock purchase plan

401(k) plan with company match

Professional Judgment Vacation Policy

11 paid holidays per year and Winter Break (typically between Christmas and New Year's Day). ADDITIONAL U.S. BENEFITS:

Medical, dental, and vision plans

Company-provided short- and long-term disability plans

Company-provided life insurance

Unique offerings of pet, legal, and supplemental life insurance

Flexible spending accounts for medical and dependent care

Accident and Hospital Indemnity plans

Supplemental AD&D

Employee Assistance Program (EAP)

Mental Health on-line digital resource

On-site, no-cost fitness center at our U.S. headquarters

Paid time off to volunteer

Additional Information

Insmed Incorporated is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Applications are accepted until the position is filled.

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