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    Research Assistant I - Houston, United States - University of Texas MD Anderson Cancer Center

    University of Texas MD Anderson Cancer Center
    University of Texas MD Anderson Cancer Center Houston, United States

    2 weeks ago

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    Description

    MISSION STATEMENT
    The mission of The University of Texas M. D.

    Anderson Cancer Center is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

    Summary


    The primary purpose of the Research Assistant I position is to provide technical assistance for carrying out the core research projects of the lab.

    The Dunbar lab is seeking a motivated individual who has an interest and passion for science and is excited and eager to be at the forefront of cutting-edge translational cancer research.

    We aim to utilize animal models of human cancer together with state-of-the-art next-generation sequencing techniques of primary patient samples to further understand the mechanisms of disease progression and drug resistance in chronic blood cancers, specifically myeloproliferative neoplasms (MPNs).

    Dr.

    Andrew Dunbar, MD, a new physician-scientist faculty member within the Department of Hematopoietic Biology and Malignancy (HBM) at MD Anderson, is deeply committed to the mentorship and growth of lab members and will work with new hires to ensure they are able to achieve their long-term career goals.


    JOB SPECIFIC COMPETENCIES
    Research Experiments and Projects
    Will assist in maintaining the lab's animal colony-ensuring proper breeding, weaning, and genotyping of individual mouse strains and litters. Will assist with setting up and maintaining experimental animal cohorts, which requires being comfortable in handling mice.

    This includes performing intermittent facial vein phlebotomy, tail vein injections, drug administration through oral gavage and/or intra-peritoneal routes, and sacrificing animals through humane methods for dissection, tissue procurement, and sample processing.

    Will assist with processing primary patient blood/bone marrow samples through density gradient separation, which requires good sterile technique, the ability to determine cell counts/viability using a microscope and hemocytometer, and the ability to viably freeze cells for later use.

    Will help establish and maintain tissue culture cell lines and prepare sterile media & solutions. This also includes monitoring and maintaining tissue culture supplies, preparing cells for cryogenic storage, and thawing/re-establishing viable cell lines.

    Laboratory Functions

    Will perform basic molecular biology and tissue culture techniques in manipulation of DNA, RNA and protein as well as primary cells and established cell lines, including polymerase chain reaction (PCR) technique, DNA/RNA extraction/quantification, western blot, etc.

    Requires techniques for handling potentially hazardous chemicals.

    Requires the ability to accurately prepare media solutions and reagents using a pH meter and balances, and the ability to handle acids, polyacrylamide solutions, flammable materials and other biohazards in accordance with institutional safety policies.

    Will perform other day-to-day tasks, including packing and mailing viably frozen cells and other reagents to collaborators as needed, working on/maintaining protocols, and ensuring sample banks, databases, etc.

    are kept up to date.

    Laboratory Maintenance
    Will be able to maintain a clean and neat work area to ensure efficient functioning. Will be able to maintain a pleasant, safe, fun, and respectable work environment. Will follow written instructions/operations manuals. Other duties as assigned.

    Education Required:
    Bachelor's degree with major course works in one of the basic sciences.

    Experience Required - none

    Experience Preferred:
    Some experience in scientific or experimental research work.


    It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.

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