beBee background
Professionals
>
Woburn
Oscar Moradei

Oscar Moradei

Experienced Medicinal Chemist

Pharmaceutical / Bio-tech

Woburn, City of Woburn, Middlesex

Social

Services offered

Accomplished project leader with 25+ years of success in drug discovery across pharmaceutical and biotechnology sectors. Recognized for managing high-impact medicinal chemistry teams and programs from early-stage discovery through preclinical and early clinical development. Strategic, results-driven, and known for operating with urgency and scientific rigor.
________________________________________
CORE COMPETENCIES
• End-to-end medicinal chemistry expertise: from HTS hit triage to GLP-tox-enabling candidates
• SAR-driven optimization using tools such as Spotfire and StarDrop
• Cross-functional project coordination, including CRO oversight and multidisciplinary integration
• Structure-based drug design, molecular modeling (MOE), and complex organic synthesis

Medicinal chemistry
Project management
Molecular modeling
Drug discovery
Organic synthesis
Approximate rate: USD$ 100 per hour

Experience

HotSpot Therapeutics Inc., Boston, MA
Senior Director (2017–2025)
Led drug discovery programs focused on immune-mediated diseases through targeting allosteric regulatory sites.
 
Epizyme Inc., Cambridge, MA
Principal Scientist (2011–2017)
Medicinal chemistry lead for histone methyltransferase inhibitor programs in oncology.

Merck-Frosst., Montreal, QC
Senior Research Scientist (2008–2010)
Research in antivirals (HIV) and metabolic disorders (diabetes).

MethylGene Inc., Montreal, QC
Team Leader (2000–2008)
Led oncology programs focused on HDAC, sirtuin, and kinase inhibitors.
 
The Ohio State University, Columbus, OH
Postdoctoral Fellow (1997–1999)
Advisor: Prof. Leo A. Paquette
• Completed the first total synthesis of Sclerophytin A and corrected its misassigned structure
• Designed and executed stereocontrolled synthetic strategies to overcome reactivity challenges

 

Education

Ph.D., Chemistry (Organic Synthesis)
University of Buenos Aires, Argentina
Dissertation: Synthetic Precursors of Thromboxane A2 and Structurally Related Analogs

M.Sc., Chemical Sciences (Organic Chemistry)
University of Buenos Aires, Argentina

 

Professionals in the same Pharmaceutical / Bio-tech sector as Oscar Moradei

Professionals from different sectors near Woburn, City of Woburn, Middlesex

Other users who are called Oscar

Jobs near Woburn, City of Woburn, Middlesex

  • Work in company

    Senior Scientist

    Superluminal Medicines, Inc.

    We are a generative biology and chemistry company revolutionizing the speed and accuracy of how small molecule medicines are created. · ...

    Boston

    3 weeks ago

  • Work in company

    Director, Medicinal Chemistry

    Bayer

    We are seeking an experienced and highly motivated Medicinal Chemist / Drug Hunter with a strong background in Chemical Biology to join our dynamic team in the Boston/Cambridge area. · ...

    Cambridge

    1 month ago

  • Work in company

    Associate Director, Computational Chemistry

    Jnana Therapeutics

    About Us · Jnana Therapeutics, a wholly owned subsidiary of Otsuka Pharmaceutical, is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases wit ...

    Boston

    6 days ago