Molecular Biologist Iii - Austin, United States - Dept of State Health Services

Dept of State Health Services

Verified Company

Austin, United States

3 weeks ago

Posted by:

Mark Lane

beBee recruiter

Description

Under the mínimal supervision of the SCID-SMA Screening Group Manager, uses expert knowledge to independently perform highly complex and highly specialized molecular genetic procedures to detect T cell receptor excision circles (TREC) or other markers for screening of severe combined immunodeficiency (SCID) and exon 7 deletions in the SMN1 gene to screen for spinal muscular atrophy (SMA) on high volume neonatal screening specimens.

Responsible for independently performing specimen and reagent preparation, data analysis and interpretation, work list evaluation, result entry, release of final results, maintenance and troubleshooting of equipment, evaluating the quality of reagents, assisting in managing material resources, and other supporting work for the laboratory.

Responsible for making significant decisions on the assay acceptability and accuracy of laboratory tests on human specimens.

Performs and reviews quality control for DNA analysis and utilizes expert working knowledge of all procedures to independently determine, troubleshoot, and release highly complex analytical test results ensuring that the analytic accuracy and continuity of testing are maintained.

Conducts the monitoring and documentation of quality assurance. Serves as a senior molecular biologist, authority and role model. Responsible for coordinating assignments, monitoring workload and staff, training personnel, and providing customer service. Evaluates current protocols, researches new procedures and provides recommendations. Participates in incorporation, evaluation, validation, and implementation of new processes, procedures and technologies. Actively participates in the safety program.

Duties are independently performed with considerable latitude, adherence to standard protocol and with extensive use of scientific knowledge and independent judgment.

Work hours/days and laboratory assignments may vary, all staff members will be required to work on Saturday as part of a rotating schedule.

This position is eligible for shift differential in accordance with DSHS laboratory policy.

Essential Job Functions:

Attends work on a regular and predictable schedule in accordance with agency leave policy and performs other duties as assigned.

EJF 1. Plans and conducts highly complex advanced molecular genetic procedures including DNA extraction and realtime quantitative polymerase chain reaction following laboratory protocol guidelines for detection of T cell receptor excision circle (TREC) or other markers for the screening of SCID and exon 7 deletions in the SMN1 gene to screen for SMA on high volume neonatal screening specimens. Performs high volume sampling of filter paper specimens and controls for all newborn screening tests. Uses technical knowledge to determine specimen acceptability. Prepares reagents and standards. Completes all documentation with required information. (35%)
EJF 2. Evaluates and interprets highly complex laboratory data on human specimens and assigns final results. Uses expert knowledge to independently identify, investigate, interpret, assess, review, order retests and resolve problems with atypical test results to ensure the accuracy of the reports. Consults with upper level personnel when necessary. Reviews and releases final test results using the laboratory information management system. Crosschecks positive mailed report verifying abnormal reports are correct. Monitors the timelines are met. Ensures rapid communication of abnormal test results to Clinical Care Coordination, Team Lead, and Group Manager. (25%)
EJF 3. Conducts the monitoring and documentation of quality control review, proficiency testing, equipment performance documentation, specimen tallies, reagent quality, and supply inventory to ensure consistently acceptable quality assurance and test performance. Investigates quality assurance problems, recommends solutions, and implements approved corrective actions. Ensures standard protocols and proper quality control procedures are followed for all the tests performed by the team. Participates in the update and development of Standard Operating Procedures and training materials. (15%)
EJF 4. Coordinates and facilitates the technical bench assignments. Ensures that specimen testing, reporting, and other essential functions are completed without delay, notifying the supervisor immediately and initiating corrective action when needed. Promotes workflow through cooperative interaction, reassignment of duties, and teamwork with supervisors, coworkers, and internal and external customers. Provides consultation and services to customers regarding specimen requirements, molecular biology technology, and interpretation of highly complex analytical test results. Conducts training and tours. Other duties as assigned include but are not limited to actively participating and/or serving in a supporting role to meet the agency's obligations for disaster response and/or recovery or Continuity of Operati