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    Research Associate, Process Development - Boulder, United States - Agilent Technologies

    Agilent Technologies
    Agilent Technologies Boulder, United States

    3 weeks ago

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    Description
    Job Description
    The world's most revolutionary biopharma companies are partnering with Agilent Technologies to advance the next frontier of medicine. Agilent continues to invest in the capacity and expansion of its Colorado operations. Join our team of professionals dedicated to the development and commercialization of nucleic acid therapeutics for life-changing, life-saving medicines.

    Position Responsibilities:

    • Understands product requirements by studying and implementing oligonucleotide project objectives and targets related to engineering and chemical requirements
    • Assists project development by developing synthetic routes, methods, and techniques in preparing, separating, purifying, analyzing, quantifying and resolving oligonucleotide process components and objectives
    • Maintains process compliance integrity by adhering to standard operating procedures (SOP's) and current good manufacturing practices (cGMP) as appropriate
    • Documents analyses by completing experiment notebooks and records; implementing process chemistry applications and analyzing results of new oligonucleotide synthesis and purification methods and processes
    • Sets-up and operates laboratory equipment by following operating instructions; troubleshooting instrumentation and method issues. Applies laboratory experience in chemistry and separations to issues of process optimization, scale-up and laboratory process transfer to mid and kilo scale GMP manufacturing
    • Executes Design of Experiments (DOE) and Proven Acceptable Range (PAR) experiments to support design space understanding and process validation as they relate to oligonucleotide synthesis, process chromatography, and other purification and isolation techniques
    • Assists with the preparation of milligram to gram quantities of active pharmaceutical ingredient (API) to support early-stage (Pre-clinical) development and toxicology studies
    • Helps with the preparation of process descriptions and the writing of technical reports to support internal technology transfer into manufacturing and support in preparation of client CMC submissions
    • Improves job knowledge by understanding emerging trends in oligonucleotide analytical methods and synthesis development; reviewing professional and technical publications; establishing personal networks and benchmarking state-of-the-art practices
    Qualifications

    • Bachelor's or Master's Degree in chemistry, chemical engineering, science or equivalent or a combination of education and or experience
    • Post-graduate, certification, and/or license may be required
    • 2+ years relevant experience for entry to this level with preference to experience in a pharmaceutical environment
    • Previous knowledge of oligonucleotide synthesis, purification, ultrafiltration, conjugation, and lyophilization is advantageous
    • Detail-oriented and can perform technical duties following standard operating procedures and general laboratory safety rules
    • Ability to work both independently and in a team setting on a variety of projects and use individual discretion to meet required project objectives and deadlines
    • Excellent math, documentation, communication and operational troubleshooting skills
    • Requires general proficiency with tools, systems and procedures to accomplish job
    #LI-DT1
    Agilent Technologies, Inc. is an Equal Employment Opportunity and Affirmative Action employer. We value diversity at all levels. All individuals, regardless of personal characteristics, are encouraged to apply.

    All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases.

    Agilent Technologies, Inc., is committed to diversity in the workplace and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please email or contact
    For more information about equal employment opportunity protections, please visit
    Pay Range
    $70,720.00-$110,500.00
    The salary range for this position may differ based on your actual work location.
    Eligible for Company Car
    No
    Benefits in Brief
    Travel Required
    No
    Schedule

    Schedule:
    Full time

    Shift
    Day
    Duration
    No End Date
    Job Function
    R&D

    #J-18808-Ljbffr
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