- You will identify preclinical models that reflect patient pathology and develop assays to use these models in the drug discovery process.
- You will design, optimize and implement cell-based assays to evaluate the mechanism of action of lead compounds.
- You will learn and participate in the development of in vivo pharmacology models or GEMM to assess target engagement in vivo.
- You will utilize your strong analytical and communication skills to interpret and summarize research findings, presenting them effectively at both internal and external meetings.
- We will rely on you to infuse the latest scientific breakthroughs, ideas, and technologies into your project to drive it forward.
- This is a unique opportunity to have a significant impact within a fast-paced, collaborative environment, and contribute to the advancement of an interesting drug discovery project on its journey toward clinical development.
- You have a Ph.
- You have effectively showcased your leadership abilities through a robust history of contributions to drug discovery programs or peer-reviewed publications.
- You have a versatile skill set in molecular and cell biology techniques, plate-based assays (e.g. AlphaLISA, HTRF, ELISA, CellTiter-Glo) and high content imaging.
- You have hands on experience with primary cell culture and genetically engineered cellular systems.
- Experience in angiogenesis and associated functional assays (e.g. wound healing, 3D cultures) is a plus.
- You are not afraid to roll-up your sleeves to move your project forward and are comfortable in a rapidly evolving research environment. Your can-do attitude is contagious.
- You can communicate clearly and enthusiastically your work to internal and external parties. You speak your mind and leverage your expertise to keep your team focused on the most impactful and translational questions.
- You are passionate about drug discovery and thrive in a highly collaborative environment.
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Scientist, Biology - Cambridge, United States - Relay Therapeutics, Inc.
Description
The Opportunity:
Our creative, collaborative, and talented biology group is looking for a strong addition to our team.
The ideal candidate will combine a deep understanding of cellular and molecular biology with experience in drug discovery to help drive one of our newest projects from early stages to clinical development.
You will contribute to the biology efforts on a dynamic and passionate multi-disciplinary drug discovery team, developing and optimizing cell-based assays to explore mode of action, identifying the appropriate preclinical models to assess target engagement and efficacy.
This is a unique opportunity to work cross functionally to build and advance a high impact program toward the clinic.
Your Role:
Your role will encompass several key responsibilities:
Your Background:
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients.
Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology.
Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets.
We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us
