- Lead Abpro's antibody discovery R&D from target to IND (investigational new drug), with a focus on immune-oncology and infectious diseases.
- Execute on all aspects of antibody generation and characterization using hybridoma, single B cell cloning and display technology platforms. including target selection, hit generation and optimization, protein expression/purification, and antibody engineering.
- Provide leadership to a team of experienced scientists and lab personnel of all experience.
- Provide and maintain state-of-the-art expertise and technical capabilities in the field of biologics discovery and identify opportunities for scientific novelty and innovation.
- Provide leadership and manage discovery programs both internally and through partnership.
- Manage external partnership research and CRO activities.
- Contribute to patent filing and scientific publications for the company.
- Ph.D. in Biochemistry, Molecular Biology, Immunology, or related field
- Minimum 10-15 years of experience in biologics drug discovery and pre-clinical development, of which at least 5 years in a leadership role
- Thorough understanding of the biologics drug discovery process from target validation and therapeutic concept through the transition to clinical development
- In-depth knowledge and technical expertise of a broad spectrum of therapeutic modalities in biologics, including mono- and multi-specific antibodies and other biologics
- Extensive experience with cutting-edge antibody discovery technologies, including hybridoma, single B cell cloning, and display platform
- Strong communication skills, written and oral
- Self-motivated and collaborative, with excellent time management skills
- Ability to work on multiple projects in a fast-paced excellence-driven environment
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Director, Head of Antibody Discovery - Woburn, United States - Abpro
6 days ago
Description
Abpro is seeking an exceptional individual to lead our antibody discovery efforts and develop a rich pipeline that leverages the unique advantages of our technology platforms.
Responsibilities:
Requirements:
Abpro Corporation is a clinical-stage biotechnology company located in Woburn, Massachusetts. Our mission is to improve the lives of mankind facing severe and life-threatening diseases with next-generation antibody therapies. Abpro's DiversImmuneTM platform has been used successfully against 300 traditionally difficult targets. The Company has a pipeline of therapies to treat cancer, eye, autoimmune, infectious diseases, and other areas.
We offer competitive salaries and generous benefits, and the opportunity to learn and grow in an employee-driven culture. We are seeking individuals with infectious enthusiasm, passion, and conviction who will be committed to our core values and mission. If you thrive in an upbeat, energetic, collaborative environment where every individual counts, we are looking for you
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