Director, Quantitative Pharmacology - San Francisco, United States - Amgen

Amgen

Verified Company

San Francisco, United States

2 weeks ago

Posted by:

Mark Lane

beBee recruiter

Description

HOW MIGHT YOU DEFY IMAGINATION?
If you feel like you're part of something bigger, it's because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world's leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It's time for a career you can be proud of.

Director, Quantitative Pharmacology

Live:

What you will do

Planning and execution of mechanistic PKPD analyses to integrate knowledge of drug design parameters, disease pharmacology, physiology, pharmacokinetics and pharmacodynamics, and to optimize selection doses and preclinical study designs.
Working closely with discovery scientists (biologists, (protein)chemist, biochemist, pharmacologist, toxicologists) to codify their knowledge and discover new insights using advanced PKPD modeling techniques.
Contributing to the analysis of preclinical PKPD data for IND and NDA/BLA filings, and documentation in appropriate reports.
Work closely with business development group to evaluate external opportunities
Build close relationships with partner functions and therapeutic areas

Win:

What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek will possess these qualifications.

Basic Qualifications:

Experience in managing and mentoring junior modelers and scientists
Ability to drive the progression of discovery and development project teams
Lead development of scientific strategy across PKDM initiatives with a focus on development of integrated PK/PD, QSP and PBPK models to aid in translation.
Develop and mentor PKDM staff. Establish modeling workflows for PKDM scientists.

Preferred Qualifications:

PhD in Pharmacokinetics, Pharmaceutical Sciences, Engineering, or related fields with equivalent professional degrees and 10+ years of experience in the Biotechnology/Pharmaceutical Industry, consulting or postdoctoral training
Expertise in PK/PD and translational modeling
Experience in supporting preclinical/clinical PK, PK/PD, and modeling & simulation components of regulatory documentations.
Excellent interpersonal, technical, and communication skills to lead crossfunctional teams
Past experience as a laboratory scientist and in a biotech environment
Excellent written and oral communication skills, attention to detail and accuracy, and interpersonal skills
Record of scientific contributions through peerreviewed articles and external presentations

Thrive:

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a salesbased incentive plan
Stockbased longterm incentives
Awardwinning timeoff plans and biannual companywide shutdowns
Flexible work models, including remote work arrangements, where possible

for a career that defies imagination
Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.