- Perform routine and non-routine internal production following standard protocols
- Directly assist in the planning and execution of laboratory experiments to develop manufacturing and purification of closed ended DNAs using the RES process.
- Maintain daily production output to enable ongoing preclinical stage research studies
- Write and review detailed experimental protocols, maintain laboratory notebooks, and manage data and material inventories
- Supporting the development of next generation DNA production efforts through process engineering and identification of key technologies to improve production performance
- Keep good records and updated electronic notebook for all executed experiments
- Prepare, analyze, and present data internally to cross functional teams
- BS. in Biology, Biochemistry, Cell Biology or related discipline and a minimum of 2 years of relevant experience
- Downstream experience with standard chromatography and/or DNA purification kits is a plus
- Experience and familiarity with Akta and TFF systems is a plus
- Knowledge of general molecular biology techniques (e.g. PCR, ligations, restriction digestions, and plasmid cloning and/or assemblies) is a plus
- Experience with enzymatic reactions is a plus
- Ability to work effectively in a dynamic and fast-paced environment
- Comfortable working both independently and as part of a team
-
Associate Scientist
1 week ago
Planet Pharma Cambridge, United Statesonsite Cambridge, MA · 6+ month contract · Required Skills: · ANIMAL HANDLING · QPCR · CELL CULTURE · ELISA · ANIMAL BREEDING · Additional Skills: · VIVO · SOP · COLLECTION · TOXICOLOGY · LABORATORY AUTOMATION · MARKETING ANALYSIS · DETAIL-ORIENTED · INVENTORY · IACUC · PHARMACOL ...
-
Associate Scientist
4 weeks ago
Randstad Life Sciences US Cambridge, United States6 Month Contract · Cambridge, MA · PR: $35-45/hour · Job Summary · We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics efforts within our department of Biotherapeutic and Medicinal Sciences as a contract role for ...
-
Associate Scientist
4 weeks ago
Planet Pharma Cambridge, United States100% Onsite in Cambridge · Biotherapeutic and Medicinal Sciences as a contract role for 6 months · Position Description: · We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics efforts within our department of Bioth ...
-
Associate Scientist
1 week ago
Rangam Cambridge, United StatesWhy Patients Need You · Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Wh ...
-
Associate Scientist
4 weeks ago
Net2Source Inc. Boston, United StatesMy name is Gaurav and I am a recruiter with Net2Source Inc. I saw your profile on one of the job boards. Our direct client is looking to hire a Scientist - II in their growing team. · Please find below the job description. · Title: Scientist - II (Associate)- Neuroscience · Durat ...
-
Associate Scientist
2 weeks ago
Pioneer Data Systems Cambridge, United StatesPosition Details: · Our client, a world-leading Pharmaceutical Company in Cambridge, MA is currently looking for a Associate Scientist to join their expanding team. · Job Title: Associate Scientist (Cell Culture, Molecular Biology) · Duration: 18 months contract, extendable up to ...
-
associate scientist
2 weeks ago
Randstad US cambridge, United Statesassociate scientist. · + cambridge , massachusetts · + posted 10 days ago · **job details** · summary · + $35 - $45.39 per hour · + contract · + bachelor degree · + category life, physical, and social science occupations · + reference48076 · job details · job summary: · As the wo ...
-
Associate Scientist
4 weeks ago
Randstad North America, Inc. Cambridge, United StatesAs the world's largest staffing and recruitment agency in the world, we can commit to find you the perfect role that gives you the opportunity to learn and grow in the life sciences arena. Utilizing a recruiter for your job search gives you access to Scientist, Associate, Chemist ...
-
Associate scientist
1 week ago
Collabera Cambridge, United StatesHome · Search Jobs · Job Description · Associate scientist · Contract: Cambridge, Massachusetts, US · Salary: $33.00 Per Hour · Job Code: 349335 · End Date: · Days Left: 28 days, 3 hours left · Apply · About the Role: We are seeking a highly skilled and experienced Research As ...
-
Associate Scientist
4 weeks ago
The Fountain Group LLC Cambridge, United StatesImmediate Opportunity for an R&D Associate Scientist located in Cambridge, MA (Onsite). · Details for the position are as follows: · Job Description: · We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics effort ...
-
Associate Scientist
3 weeks ago
Eli Lilly and Company Cambridge, United States Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve th ...
-
Associate Scientist
2 weeks ago
Simcere Zaiming Cambridge, United StatesSimcere Zaiming is expanding its North American presence with a dynamic drug discovery team based in Cambridge, Massachusetts. We are on the lookout for innovative, driven, and autonomous Associate Scientist to enhance our preclinical research division. This role presents an exci ...
-
Associate Scientist
2 weeks ago
BioSpace Cambridge, United StatesJob Details · At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need th ...
-
Associate Scientist
4 weeks ago
Eli Lilly and Company Cambridge, United States Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve th ...
-
Associate Scientist
2 weeks ago
Aequor Technologies LLC Cambridge, United StatesFully onsite 8-5. Cambridge site. · Must have: HPLC expertise and hands on lab experience. · Job Details: · Master's degree or Bachelors' degree & 2+ YOE · To perform experiments, organize data and analyze results under minimal supervision. With minimal supervision, plans, conduc ...
-
Associate Scientist, Biology
1 week ago
ProPhaGro2023 Cambridge, United StatesAssociate Scientist, Biology · Cambridge, MA · 2.5 month contract to start (benefits offered) · Pay: $40-58hr · (Must be a US citizen- C2C and visa sponsorship not available) · How will your role help us transform hope into reality? · You will have the opportunity to contribute t ...
-
Associate Research Scientist
3 days ago
Eclaro Cambridge, United StatesAssociate Research Scientist · Job Number: 24- · Be part of a company that delivers life - changing healthcare solutions. Eclaro is looking for a Associate Research Scientist for our client in Cambridge, MA. · Eclaros client is among the worlds largest pharmaceutical companie ...
-
Associate Research Scientist
1 day ago
Axelon Services Corporation Cambridge, United StatesJob Description: The Mechanism of Cancer Resistance (MoCR) Thematic Research Center (TRC) is seeking a highly motivated Associate Scientist to support Discovery Biology research programs at our facility in Cambridge, MA. The ideal candidate will contribute to our discovery pipeli ...
-
Associate Scientist, Biology
6 days ago
The Steely Group Cambridge, United StatesYou will have the opportunity to contribute to an early drug discovery program in the Targeted Protein Degradation space. This position offers the unique opportunity to directly impact a growing portfolio of targeted therapies in a fast-paced and innovative research environment. ...
-
Associate Scientist
2 weeks ago
Aura Biosciences Brighton, United StatesJob Description · Job DescriptionSalary: · About Aura: · At Aura, our mission is to develop a new class of oncology targeted therapies that deliver meaningful therapeutic benefit to a range of cancer indications with high unmet need in which we believe we can establish a new sta ...
Senior Associate Scientist - Cambridge, United States - Generation Bio Co.
Description
Generation Bio is innovating genetic medicines to provide durable, redosable treatments for people living with rare and prevalent diseases.The company's non-viral platform incorporates a novel DNA construct called closed-ended DNA, or ceDNA; a unique cell-targeted lipid nanoparticle delivery system, or ctLNP; and a highly scalable capsid-free manufacturing process that uses its proprietary cell-free rapid enzymatic synthesis, or RES, to produce ceDNA.
The platform is designed to enable multi-year durability from a single dose, to deliver large genetic payloads, including multiple genes, to specific tissues, and to allow titration and redosing to adjust or extend expression levels in each patient.
RES has the potential to expand Generation Bio's manufacturing scale to hundreds of millions of doses to support its mission to extend the reach of genetic medicine to more people, living with more diseases, around the world.
We are a thriving, collaborative, creative community of 110 people with diverse talents, beliefs, and experiences headquartered in Cambridge, Massachusetts.
SUMMARY
Generation Bio seeks an energetic, highly motivated, and dynamic principal associate scientist to support daily operations within the Research Production team.
The Research Production team is responsible for the upstream enzymatic synthesis and downstream manufacturing of drug substance to support pre-clinical trials.
A successful candidate will help with in-house manufacturing of key materials and optimize our production process to support manufacturing DNA gene therapy molecules.
We are seeking motivated individuals with experience and familiarity with enzymatic synthesis, standard chromatography techniques, TFF, DNA purification kits, and molecular biology techniques such as DNA manipulations including PCR, ligations, restriction digestions, and plasmid cloning.
This will be a key role in a dynamic, innovative team.RESPONSIBILITIES:
Primary responsibilities for this role include:
QUALIFICATIONS:
POSITION:
Full-Time, Exempt
EEOC Statement:
Generation Bio believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants.
We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race (to include traits historically associated with race including, but not limited to, hair texture, hair type, hair length, and protective hairstyles such as braids, locks, twists, hair coverings, and Bantu knots), color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Generation Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
