- Collaborate with managers to develop analytical methods (LC-UV and/or LC-MS) for purity analysis and impurity characterization of small molecules, peptides, PMOs, and PPMOs.
- Provide analytical support for internal discovery and development activities, including stability sample analysis, forced degradation sample preparation, and characterization.
- Draft and review analytical protocols and reports for in-house analytical tasks, and compile analytical source documents for regulatory submissions.
- Perform regular maintenance on analytical equipment, HPLC systems, balances, pH meters, etc., and assist in setting up new instruments.
- Foster a culture of collaboration, innovation, and cutting-edge research focused on scientific excellence, open communication, and continuous improvement.
- Ph.D. in Chemistry or related field with at least 1 year of experience, or an MS degree with over 5 years of relevant experience in analytical development within the pharmaceutical/biotech sector. The job title will be determined based on the candidate's experience level.
- Hands-on experience in method development using HPLC and MS (e.g. TOF, QTOF, etc.) is essential.
- Preferred experience in method transfer, qualification, and validation of chromatographic methods (HPLC, GC, LC-MS, CE, etc.).
- Good understanding of current Good Manufacturing Practices (cGMPs) or Good Lab Practices (GLP) is beneficial.
- Knowledge of analytical support for early discovery and formulation development is advantageous.
- Ability to effectively prioritize tasks, meet tight deadlines, and thrive in a fast-paced and dynamic team environment.
-
Director, Analytical Development
1 week ago
Spyre Therapeutics Boston, United StatesDirector, Analytical Development & Quality Control · Spyre Therapeutics (NASDAQ: SYRE) is a biotechnology company aiming to address the needs of the millions of people living with inflammatory bowel disease (IBD) by advancing potentially best-in-class long-acting antibodies, rat ...
-
Associate Director, Analytical Development
1 week ago
PepGen Boston, United StatesReporting to the Senior Director, Analytical Development & QC, the Associate Director of Analytical Development will be acting as analytical project lead, responsible for supporting the analytical development needs of PepGen's pipeline. In addition, this position will be required ...
-
Oracle Analytics Cloud Developer
18 hours ago
Apex Systems Boston, United StatesJob#: · Job Description: · Apex Systems is a world class services business that incorporates industry insights and experience to deliver solutions that fulfill our clients' digital visions. · Apex has an opportunity for an Oracle Analytics Cloud Developer to join our team in a f ...
-
BI/Data analytics Developer
18 hours ago
Teamware Solutions Boston, United StatesMust have key skills-H2O+sagemaker..secondary- AWS, openshift, kubernetes, MLflow, jenkins, brickbucket · BI/Data analytics Developer ...
-
Oracle Analytics Cloud Developer
1 week ago
Apex Systems Boston, United StatesApex Systems is a world class services business that incorporates industry insights and experience to deliver solutions that fulfill our clients' digital visions. · Apex has an opportunity for an Oracle AnalyticsCloud Developer to join our team in a fast-paced Financial Services ...
-
Oracle Analytics Cloud Developer
1 week ago
Apex Systems Boston, United StatesApex Systems is a world class services business that incorporates industry insights and experience to deliver solutions that fulfill our clients' digital visions. · Apex has an opportunity for an Oracle AnalyticsCloud Developer to join our team in a fast-paced Financial Services ...
-
Director, Quantitative Development
1 week ago
Fidelity Investments Boston, MA, United StatesJob Description: · The Role · Fidelity's Asset Management Technology Division is seeking a Director of Quant Development to join their Fixed Income Embedded Quant Development Team. This is a core software engineering role in our dynamic and fast-paced quantitative development tea ...
-
Associate Director, Medical Analytics
2 weeks ago
Argenx SE Boston, United Statesargenx is a global immunology company committed to improving the lives of people suffering from severe autoimmune diseases and cancer. Partnering with leading academic researchers through its Immunology Innovation Program (IIP), argenx aims to translate immunology breakthroughs i ...
-
Quantitative Specialist
1 week ago
Ceres Group Boston, United StatesThe Investment Research Services Team within Asset Management provides analytic solutions and data management services to clients in quantitative research, portfolio management, and senior investment leadership. · Position Description · This role is part of a specialized team tha ...
-
Millar Associates Boston, United StatesLarge Credit Hedge Fund · Real Estate Debt Instruments, Bank debt, Bonds, Equity, & Derivatives · This truly outstanding alternative asset manager has nearly $80 billion across a range of Structured Credit, CLOs, Loans, High Yield, etc., now seeks to hire an experienced to hire a ...
-
Principal Quantitative Developer
1 week ago
Fidelity Investments Boston, United StatesJob Description: · The Role · As one of the principal quant developer on the team, you blend investment management and technical expertise with a passion for delivering results. You will be 'embedded' within the quantitative research team and you will partner with the investment ...
-
Principal Quantitative Developer
1 week ago
Fidelity Investments Boston, United StatesJob Description: · The Role · As one of the principal quant developer on the team, you blend investment management and technical expertise with a passion for delivering results. You will be 'embedded' within the quantitative research team and you will partner with the investment ...
-
Hogan Lovells Boston, United StatesKeen to become part of a truly global, collaborative team of professionals? Your journey begins here. · * Consult with case teams and clients to develop analytics and machine learning strategies and custom workflows, and ensure their successful execution in complex litigation and ...
-
Director, Quantitative Development
1 week ago
Fidelity Investments Boston, United StatesJob Description: · The Role · Fidelity's Asset Management Technology Division is seeking a Director of Quant Development to join their Fixed Income Embedded Quant Development Team. This is a core software engineering role in our dynamic and fast-paced quantitative development tea ...
-
Product Manager Technical
1 week ago
Ceres Group Boston, United StatesJob description · We are seeking an equity market professional for the role of Head of Product, Product Manager. The Head of Product will be the primary driver of product strategy and will execute upon that strategy as the manager of a team of product developers and quantitative ...
-
Manager, Campaign Insights
6 days ago
Mediahub Worldwide Boston, United StatesBusiness Overview · Mediahub is one of the three major global media agencies within IPG Mediabrands with over 1000+ employees worldwide. We are an award-winning agency built for brands who are challenging and disrupting the status quo. Our organization is focused on challenging ...
-
Revenue Operations Lead
1 week ago
Cato Networks Boston, United StatesThe Revenue Operations Lead will play a pivotal role in optimizing revenue generation processes, driving efficiency, and facilitating cross-functional collaboration within the organization. With a strong focus on analytics and project management, this role will be responsible for ...
-
Enterprise Analytics Program Manager
1 week ago
Executive Office of Technology Services and Security Boston, United StatesEnterprise Analytics Program Manager - FT Contract Opportunity · Come join the Massachusetts Data Office as the Enterprise Analytics Program Manager and help us build the future of data-driven government for Massachusetts · About EOTSS and the Massachusetts Data Office · The Exec ...
-
Health Analytics Specialist
1 week ago
Noblis, Inc. Boston, United StatesResponsibilities · This is for potential upcoming opportunities. We will review your resume and reach out when an opportunity is available. · The Advanced Research Projects Agency for Health (ARPA-H) is a research funding agency that supports transformative biomedical and health ...
-
Analytics Engineer
5 days ago
firstPRO, Inc Boston, United StatesfirstPRO is now accepting resumes for a Analytics Engineer role. This is a 6+month contract role. · As a Senior Analytics Engineer, you will support the BI lead on Glossier's data pipeline and ecosystem from end to end. You will be partnering with multiple cross functional busine ...
Scientist I/II, Analytical Development - Boston, United States - PepGen
Description
Scientist I/II, Analytical Development
The Scientist in Analytical Development plays a crucial role in PepGen's Analytical Development group. This position offers great opportunities to utilize cutting-edge instruments for researching potential drug candidates to develop groundbreaking therapies for patients with neuromuscular conditions. The selected candidate will be responsible for leading method development, providing analytical support for in-house drug discovery and development projects, and collaborating closely with experienced CMC and discovery teams. The role involves developing and validating analytical methods for various chemical entities such as peptides, oligos, and PepGen's proprietary Enhanced Delivery Oligonucleotides (EDOs) to ensure high-quality therapies for patients. The position is laboratory-based and requires on-site presence five days a week.
Responsibilities:
Requirements:
About the Team:
We are a team of dedicated and innovative scientists focused on analytical development and quality control of the revolutionary EDO platform at PepGen. Our team values transparent communication and is seeking a collaborative team member who shares our values and enthusiasm for the potential of our EDO platform to make a meaningful impact on patients' lives.
About PepGen
PepGen is a biotech company advancing next-generation oligonucleotide therapies for neuromuscular diseases. Our goal is to harness the potential of nucleic acid therapeutics through our proprietary Enhanced Delivery Oligonucleotide (EDO) platform. We are rapidly expanding our team at our U.S. headquarters in Boston, Massachusetts, and exploring the application of this technology across various indications.
EEO Statement
PepGen is an Equal Opportunity Employer dedicated to fostering a diverse workforce. We welcome applications from qualified individuals without regard to race, color, religion, national origin, age, gender, sexual orientation, disability, or veteran status.
Recruitment & Staffing Agencies: PepGen does not accept unsolicited agency resumes. We are currently partnering exclusively with The Bowdoin Group for all our recruitment needs. Thank you.
