- Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week
- Group Dental, Vision, Life, AD&D and Disability coverage
- Paid Education Vacation and Sick Leave
- Paid institutional holidays, wellness leave, childcare leave and other paid leave programs
- Teachers Retirement System definedbenefit pension plan and two voluntary retirement plans
- Employer paid life, AD&D and an illnessrelated reduced salary pay program
- Health Savings Account and Dependent Care Reimbursement flexible spending accounts
- Fertility benefits
- State of Texas longevity pay
- Extensive wellness, fitness, employee health programs and employee resource groups
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Postdoc Fellow - Houston, United States - MD Anderson Cancer Center
Description
Full-time experimental postdoctoral fellow positions are available in Professor Yiwen Chen's lab. Dr.Chen's lab focuses on deciphering the cell signaling, epigenetic/epitranscriptomic and RNA-based regulation mechanism of cancer immunology in solid tumors, neural stem cells and cancer stem cells of brain tumor.
The Chen lab has great expertise in combining computational with high-throughput approaches such as single-cell multi-omics profiling (e.g., scRNA-seq and Perturb-seq), CRISPR/Cas9, mass spectrometry, ChIP-seq, RNA immunoprecipitation (RIP)-seq, eCLIP-seq (enhanced CrossLinking and Immunoprecipitation followed by high-throughput sequencing) and Ribosome Profiling (Ribo-seq), to decipher cryptic translation of the non-canonical open reading frames (ORFs) and/or noncoding RNA (ncRNA)/RNA-binding protein (RBP)-mediated regulatory circuitries.
The experimental postdocs will leverage the high-throughput assays developed/established in the lab to study the cell signaling, epigenetic/epitranscriptomic and RNA-based regulation that is important for tumor immunity in solid tumors, neural stem cells and cancer stem cells of brain tumors, as well as develop T cell-based and/or combinatorial cancer immune therapies.
The former postdoctoral trainees from the Chen lab have excelled in both academia and industry, including 4 past/current postdoctoral trainees from Chen lab who are/will become a faculty in U.S.
or China.Chen lab representative publications include:
Nature Structural & Molecular Biology (2023, PMC , Science (2023,
PMID:
, Science Advances (2023, PMC , The Journal of Clinical Investigation (2023, PMC , Journal of Experimental Medicine (2021, PMC , Genome Biology (2021, PMC , The Journal for ImmunoTherapy of Cancer (2021, PMC , Nature Methods (2018, PMC , Nature Genetics (2017,
PMID:
, Nature Communications (2017, PMC , and Trends in Genetics (2016, PMC
LEARNING OBJECTIVES
The postdoctoral trainee will learn how to conduct highly interdisciplinary research at the interface of computational/functional genomics, RNA biology, cancer biology, cancer immunology and neural stem biology.
ELIGIBILITY REQUIREMENTS
Applicants should have a Ph.
D. degree (or equivalent) in biomedical sciences.
Strong background in one or more of the following areas:
molecular biology; protein/RNA biochemistry; transcriptional/epigenetic regulation; cell signaling; virology; immunology; T-cell biology; cancer biology. Mouse model experience and bioinformatics/genomics/proteomics expertise are not required, but highly desirable. All applicants should have good spoken and written communication skills.
ADDITIONAL APPLICATION INFORMATION
Interested applicants should send i) a cover letter briefly describing your previous experience and your future research interest/plan, ii) a curriculum vitae, and iii) contact information of at least three references to Dr. Yiwen Chen ).
POSITION INFORMATION
MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA ) . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.
MD Anderson offers compensated trainees:
