- Develops and performs biochemical and cell-based assays, including ADCC/ADCP/CDC reporter assays
- Perform antibody cell-binding assays and multicolor FACS analysis of antibody binding and/or cell marker staining
- Measure cytokines, or other analytes, from cell-based assays or plasma/serum samples using immunoassay platforms such as MSD or ELISA
- Prepare and isolate primary cells, such as CD4+ T cells and monocytes, for in vitro assays
- Thaw, maintain and culture cell lines and primary cells for in vitro assays
- Experience with label-free BLI binding studies to investigate competition and off-target binding of lead antibody panels is a plus
- Responsible for data analysis and reporting
- Tracks and documents assay performance
- Continually provides recommendations to improve on process efficiency and research quality
- Other duties as assigned
- BS/BA degree in scientific field and 2+ years of in vitro pharmacology experience; Preferred experience includes: primary cell culture, and related assay development, liquid handling automation and LIMS systems, antibody screening and related in vitro assays OR
- MS/MA degree in scientific field and some relevant industry experience OR
- PhD in biology or related field preferred and some experience with cell culture and cell-based in vitro assays, development and optimization of in vitro biological assays is required Preferred experience includes: primary cell culture, and related assay development, liquid handling automation and LIMS systems, antibody screening and related in vitro assays
- Experience with flow cytometry and ability to independently perform multicolor flow cytometry experiments and data analyses (FlowJo)
- Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools, such as MSD, plate readers, automation. Experience with label-free technologies, such as Octet BLI and/or SPR is a plus
- Working knowledge of primary cell culture, primary cell assays, cell lines, and transient transfections
- Collaborative and highly motivated
- Good knowledge of scientific principles, methods, and techniques
- Ability to work as part of a team
- Strong computer skills and experience with Prism, Excel, Word, etc.
- Good communications, problem-solving, analytical thinking skills
- Detail oriented
- Ability to meet deadlines
- Good project management skills
-
Scientist, In Vitro Pharmacology
2 weeks ago
Neurocrine Biosciences Inc. San Diego, United StatesWho We Are: · At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering ...
-
Sr. Principal Scientist, In Vitro Pharmacology
2 weeks ago
Neurocrine Biosciences Inc. San Diego, United StatesWho We Are: · At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering ...
-
Neurocrine San Diego, United StatesWho We Are:At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for ...
-
Principal Scientist I, In-Vitro Pharmacology
5 days ago
Crinetics Pharmaceuticals San Diego, United StatesPrincipal Scientist I, In-Vitro Pharmacology · Categories: Biology · Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scie ...
-
Neurocrine San Diego, United StatesWho We Are:At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for ...
-
Neurocrine Biosciences San Diego, United StatesWho We Are: · At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering ...
-
Associate Director, Bioanalysis
2 weeks ago
WuXi AppTec San Diego, United StatesOverview · HD Biosciences Inc. a WuXi AppTec company, offers biology-focused preclinical drug discovery services to biotech and pharmaceuticals. We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead d ...
-
Sr. Scientist, DMPK
2 weeks ago
Neurocrine Biosciences San Diego, United States Full timeWho We Are: · At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering ...
-
Associate Scientific Director, Bioanalytical
2 weeks ago
Neurocrine Biosciences San Diego, United States Full timeWho We Are: · At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering ...
-
Johnson & Johnson San Diego, United StatesJohnson & Johnson is recruiting for an Associate Scientist in the Lead Evaluation and Cellular Pharmacology team located in La Jolla, CA. · At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex dise ...
-
Sr. Scientist, Translational Biology
2 weeks ago
Zentalis San Diego, United StatesJob Description · Job DescriptionSalary: $125-148k · JOB SUMMARY: · Responsible for leading research on translational projects focused on small molecule drug combinations and understanding MoA. Generate robust datasets that will have a direct impact on our oncology drug discover ...
-
Senior Scientist
1 week ago
BioPhase San Diego, United StatesAre you a highly self-motivated, dynamic scientist passionate about cancer immunotherapy? We're looking for a Scientist II/Senior Scientist to join our team and report directly to the Director of Pharmacology. In this role, you'll be at the forefront of groundbreaking research, d ...
-
Senior Scientist, Oligonucleotide Biology
1 week ago
Johnson & Johnson San Diego, United StatesJob Description · Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist, Oligonucleotide Biology (In vitro)-RNA, Gene Therapy & Delivery located in La Jolla, CA. · At Johnson & Johnson, we believe healt ...
-
Principal Scientist, Pharmacology
2 weeks ago
Janux Therapeutics Inc. San Diego, United StatesAs a member of the pharmacology group, we seek a scientifically curious and motivated individual with an ability to work in a fast-paced environment. The Principal Scientist will develop and execute the bioanalytical method development to support nonclinical and clinical sample a ...
-
Principal/Senior Scientist, Discovery
4 weeks ago
Lexeo Therapeutics San Diego, United StatesAbout Lexeo · Lexeo Therapeutics is a New York City-based, clinical-stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimer's disease ...
-
Sr. Principal Scientist, Biologics Research
2 weeks ago
Neurocrine Biosciences Inc. San Diego, United StatesWho We Are: · At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering ...
-
Research Associate II
2 weeks ago
WuXi AppTec San Diego, United StatesOverview · HD Biosciences, Inc. (San Diego), a WuXi AppTec Company, is expanding its in vivo Pharmacology team. We're seeking a highly skilled and motivated Research Associate III to support our in vivo pharmacology team for various projects. · Responsibilities · Essential Job Fu ...
-
Associate Director, Bioanalysis
2 weeks ago
WuXi AppTec San Diego, United StatesJob Description · HD Biosciences Inc. a WuXi AppTec company, offers biology-focused preclinical drug discovery services to biotech and pharmaceuticals. We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and ...
-
Principal Scientist, DMPK Project Representative
8 hours ago
Rapport Therapeutics San Diego, United StatesAs a word, Rapport describes relationships characterized by understanding, communication, teamwork, and trust. We reflect those qualities in our daily work, where we operate as one committed team that captures the collective knowledge and experience of all our members to maximall ...
-
Senior Research Associate
2 weeks ago
Tentarix Biotherapeutics San Diego, United StatesAbout the Company: · Tentarix Biotherapeutics is an exciting company with a game-changing technology platform that allows for the discovery of next generation, multi-specific investigational drugs, called Tentacles, to address limitations of existing cancer, autoimmune and other ...
TEMP - Scientist, In Vitro Pharmacology - San Diego, United States - Neurocrine Biosciences Inc.
Description
Who We Are:
At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values.
We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.
What We Do:
Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options.
The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas.
For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions.
We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVieAbout the Role:
Our dynamic team is seeking a motivated, collaborative, and experienced scientist to support our in vitro biochemical and cell-based assay development, screening, and lead panel characterizations for our antibody discovery programs.
The qualified individual will work closely with team members to design, develop and execute assays to deliver robust and high-quality decision-making data.
The position requires excellent scientific, technical and laboratory skills, strong organizational and communications skills, and enthusiasm in contributing to a fast-paced organization focused on discoveries of novel and differentiated therapeutic candidates.
_Your Contributions (include, but are not limited to):
Requirements:
Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.
We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements.
We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.
