Master Thesis - Sanford, MI, United States - Matrix Dynamics

James Miller

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James Miller

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Freelance
Description
Full time

Sanford, MI '102414


We are Helmholtz Munich, located in Sanford, MI ' In a rapidly changing world, we are dedicated to discovering breakthrough solutions for better health.


Our research is focused on metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health.

We excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.

Through our research, we lay the groundwork for medical innovation.

Together with our partners, we strive to accelerate the transfer of our research so that laboratory ideas can reach society and improve people's quality of life at a rapid pace.

This is what drives us. Why not join us and make a difference?

At the Institute of Structural Biology at Helmholtz Munich, we study the structure and function of the PURA protein.

Our main goal is to understand PURA's cellular functions and the molecular consequences of a PURA deficiency in patients with PURA syndrome.

To achieve this, we use genetically modified immortalized cell lines and patient-specific induced pluripotent stem cells (iPSCs).

Our high-throughput techniques have already provided us with initial insights into PURA's interactome and its potential role in various pathways.

We are now seeking to validate these findings and identify specific molecular mechanisms that contribute to this severe disorder. Ultimately, our aim is to provide information that can lead to the development of treatment strategies for PUR

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