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    Scientist-ADME - Hayward, United States - Frontage Lab

    Frontage Lab
    Frontage Lab Hayward, United States

    2 days ago

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    Description

    Company:
    Frontage Labs., Inc.


    Division/Department:

    QDI

    Reports to:
    VP, ADME

    Full-time


    Location:
    Hayward, CA

    Job/Req.

    Job Summary


    Quintara Discovery (QDI), a wholly owned subsidiary of Frontage Laboratories in the San Francisco Bay Area, is a dynamic and growing biopharma CRO with a proven track record of working with leading biopharmaceutical companies, emerging start-up companies, universities and leading research institutes.


    We are looking for a highly motivated Scientist to develop and conduct biochemical and/or cellular assays in the field of in vitro ADME to evaluate potential therapeutics.

    Prior experience in ADME assays including drug metabolism, drug transporter, CYP450, PPB and measurements of physicochemical properties is required. Proficient knowledge of LC-MS, enzyme kinetics measurements, and/or cell culture is highly desirable.

    The candidate needs to have a good understanding of small molecule drug discovery processes and experience in a discovery project is preferred.

    The scientist is expected to be proficient in assay design, trouble-shooting, and data analysis. This position requires working with an interdisciplinary team of medicinal chemists, DMPK scientists, analytical chemists and pharmacologists.


    • Experience in ADME assays required
    • Prior industry experience strongly preferred but not required
    • Experience in small molecule drug discovery and/or LC-MS strongly preferred
    • Ability to multitask and deliver results with high degree of attention to details to drive projects forward in a timely manner
    • Strong analytical thinking and knowledge of common statistical software
    • Organized, self-motivated, and proactive
    • Excellent written and verbal communication and presentation skills
    Essential Duties & Responsibilities


    List below the major areas of responsibility of the job in descending order of importance (most important to least important).

    Indicate the approximate percentage of time spent on each responsibility (note the total of all percentages must equal 100%, 3-5 responsibilities is normal but may vary).

    Under each responsibility, summarize the specific duties required to perform the job.

    Give as much detail as necessary to fully explain the job and consider:


    • Whether the reason the job exists is to perform that function and whether removing the function would fundamentally change the job;
    • Whether serious consequences would arise if someone in this job is not required to perform a particular function/s;
    • The number of employees available to perform the function or among whom the function can be distributed; and,
    • The degree of expertise or skill required to perform the function.
    % of Time

    Duties & Responsibilities

    35%

    Perform experiments according to study protocols

    25%

    Analyze experimental data

    10%

    Ability to troubleshoot and solve basic technical and instrumental issues

    10%

    Writing up protocols and reports

    5%

    Perform project communication with client, study director, and project management team

    15%

    Mentor and train junior scientists

    100%

    Minimum Job Requirements & Qualifications

    Describe the minimum level of formal education and experience required to successfully perform the job

    as well as any required certification, licensure or registration. KSAs may include language requirements, required computer ability, communications skills, etc.


    Educational/Training Requirement:
    Ph.
    D degree in chemistry, biochemistry or a relevant field or M.S degree with 7+ years relevant experience


    Experience:
    0-3 years industrial experience in related scientific fields


    Licenses/Certifications (if applicable):

    Knowledge, Skills, and Abilities (KSAs):
    Supervisory Responsibility

    List the job titles that directly report to this job (formal supervision).

    Travel Requirements

    Estimate the percentage and nature (i.e., domestic or international) of travel; if no travel is required, indicate 0%). 0%

    Frontage Laboratories Inc. is an equal opportunity employer.

    All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

    Americans with Disabilities Act (ADA)


    PHYSICAL DEMANDS and work environment CHECKLIST


    PHYSICAL DEMANDS


    The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

    These may include lifting, pushing, climbing, degree of eyestrain, sitting for extended periods of time, prolonged standing, etc.

    Frequency refers to the amount of time one is engaged in the activity; please estimate time by checking the appropriate boxes.

    Physical Demands

    Physical Demand

    None

    Rarely

    Occasionally

    Frequently

    Constantly

    Weight

    Standing

    x

    Walking

    x

    Sitting

    x

    Lifting

    x

    Up to 10 pounds

    Carrying

    x

    Up to 10 pounds

    Pushing

    x

    Choose weight

    Pulling

    x

    Choose weight

    Climbing or balancing

    x

    Stooping, kneeling, crouching

    or crawling

    x

    Reaching with hands/arms

    x

    Using hands to finger, handle, grasp or feel

    x

    Talking

    x

    Hearing

    x

    Tasting or smelling

    x

    Repetitive motions

    x

    Seeing

    x


    • Note: Any special physical demands should be clearly communicated to any applicants applying for this job and all employees occupying this job.
    Does this job have any special vision requirements? Check all that apply.

    Close vision (clear vision at 20 inches or less)

    Distance vision (clear vision at 20 feet or more)

    x Color vision (ability to identify and distinguish colors)

    Peripheral vision (ability to observe an area that can be seen up and down or to the left and right while eyes are fixed on a given point)

    Depth perception (three-dimensional vision, ability to judge distances and spatial relationships)

    x Ability to adjust focus (ability to adjust the eye to bring an object into sharp focus)

    No special vision requirements


    WORK ENVIRONMENT


    Work environment characteristics described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.


    Describe in the box below:

    • If a job is required to work or irregular hours (overnight, weekends, overtime, etc.);
    • Any hazardous or unusual conditions associated with the physical environment this job works in (outside, in inclement weather, exposure to toxic materials, etc.);
    • Other unusual working conditions like extreme deadlines, pace of work, noise, etc.; and,
    • How often or for how long someone in this job is exposed to these conditions.
    There are no unusual hazardous conditions in a bioanalytical lab. It is a safe working environment by following standard lab safety codes and dress.
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