Research Technician Iii - Houston, United States - Baylor College of Medicine

Baylor College of Medicine

Verified Company

Houston, United States

3 weeks ago

Posted by:

Mark Lane

beBee recruiter

Description

Summary:

The Foulds laboratory is a dedicated translational and molecular oncology research program, rich with individual expertise and collaborative studies, which focuses on understanding mechanisms of endocrine therapy and CDK4/6 inhibitor resistance and generating new and optimizing current treatment strategies for ER+ breast cancer patients.

In order to develop precision diagnostics, the lab is interested in delineating mechanisms of resistance to standard-of-care therapeutics and metastasis for mainly ER+ breast cancers with some work on triple-negative breast cancers.

The successful applicant is expected to carry out independent experiments (after any needed hands-on training) and work in collaboration with other members of the laboratory.

Selected methodologies include protein, RNA, and DNA isolation from cancer cells, chromatin immunoprecipitation, RNA-sequencing, immunoblotting, cell culture, and ex vivo patient-derived xenograft (PDX) organoid culture as desirable.

The laboratory's work involves breast cancer cell lines and state-of-the-art PDX mouse models. Cross-training and transparency among the team is highly encouraged and practiced.

Job Duties:

Prepares and conducts laboratory research experiments.
Collects, compiles and analyzes data
Conducts literature searches and summarizes information in an appropriate format for a particular study.
Documents results of experiments.
Selects, evaluates and applies techniques used in routine research.
Prepares figures and assists in writing related to experiments performed.
Maintains general lab environment that includes but not limited to, equipment maintenance and repairs, organization, and cleanliness of the lab.

Minimum Qualifications:

Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
One year of relevant experience.

Preferred Qualifications:

Master's degree in basic science or a related field.
Experience with animal husbandry is preferred. The laboratory's work involves cell lines and stateoftheart mouse models.
Prior experiences in tissue culture and basic molecular biology techniques (e.g., PCR, DNA purification, Western blot,etc) are required.
Preferred Knowledge about molecular biology and cancer biology.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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