- Perform quantitative LC-MS/MS (Liquid Chromatography Mass Spectrometry) analysis of small molecules from various bio-matrices in vivo and in vitro to support PK/PD, ADME, efficacy and exploratory toxicology studies.
- Operate, perform routine maintenance, and support the troubleshooting of AB Sciex LC-MS/MS systems.
- Maintain excellent documentation of all work including LIMS, test methods, and protocols.
- Work closely with multiple teams across Discovery and DMPK-BA to support bioanalysis.
- Bachelor's Degree, or equivalent education, with typically 3 or more years'
- Experience with quantitative bioanalysis of small molecules.
- Hands-on experience using Triple Quad MS is required.
- Experience operating and troubleshooting current LC-MS/MS platforms (Agilent HPLCs, Leap/CTC PAL autosamplers, Sciex API-5500/ triple quad Mass Spectrometers) and software (e.g. Discovery Quant, Analyst, Electronic notebook, LIMS) is highly preferred.
- Experience with protein precipitation, liquid/liquid extraction, and solid phase extraction preferred.
- Experience with liquid handling robotics preferred.
- Experience with chromatographic and analytical methodologies.
- Ideal candidate is detail oriented and committed to generating high-quality results within tight deadlines and across different projects.
- Proven ability to work independently or under minimal supervision in a high-throughput environment to design and conduct experiments, interpret, document, and communicate results, as well as in a team environment to collaborate successfully across other groups within R&D.
- Strong communication, interpersonal, and presentation skills.
- Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
- Learns fast and can change course quickly where indicated.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation, and manages innovation to reality.
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Associate Scientist I/II - North Chicago, United States - AbbVie, Inc
Description
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.
We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio.
For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.Job Description
Quantitative, Translational & ADME Sciences Department at AbbVie has an open position for an Associate Scientist II position in North Chicago, IL.
The successful candidate will be responsible for non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples, including data analysis and interpretation.
Key Responsibilities Include:
experience)
Key Leadership Competencies:
Additional Information
Applicable only to applicants
