Postdoctoral Fellow, Tissue Proteomics - Andover, United States - Pfizer

Pfizer

Verified Company

Andover, United States

3 weeks ago

Posted by:

Mark Lane

beBee recruiter

Description

Why Patients Need You

What You Will Achieve

The Liquid Chromatography-Mass Spectrometry (LCMS) Biomarkers/Biomeasures team plays a vital role in this mission through the quantification of therapeutic targets utilizing state-of-the-art proteomics techniques.

We are seeking a highly motivated Postdoctoral Fellow with experience in mass spectrometry-based proteomics, bioinformatics or machine learning interested in continuing their scientific development in a highly dynamic environment here at Pfizer.

In this role, the Postdoctoral Fellow will generate comprehensive proteome-wide knowledge of protein targets in tissues as proteome maps and will drive forward the development of bioinformatic methods that integrate different proteomics data modalities.

This project is expected to have impact on our approach to target feasibility assessment and will lead to strong publications.

How You Will Achieve It

In your new role, you will leverage advanced mass spectrometry to generate data to combine with bioinformatics approaches.

You will also work on the MS-based proteomics outputs generated from variety of search engines to create a deeper understanding of protein expression in tissue organ-specific data repositories that would accelerate biomeasure assay development.

You will also establish research collaborations, present at conferences, and lead or contribute to publications.

Qualifications:

Must-Have

in Proteomics, Biological Sciences, Bioinformatics, Statistics, Analytical Chemistry or a related field with experience in one or more of the following areas as demonstrated through at least one first-author publication: Computational biology, Bioinformatics, Proteomics, Machine Learning.

No more than 2 years of postdegree experience.
Willingness to make a minimum 2year commitment.
Experience with labelfree quantification, data dependent or independent acquisitions (DDA, DIA) methods
Previous experience with large scale proteomics datasets
Proficiency in programming languages such as R or Python
Experience with proteomics search engines and databases
Experience with advanced proteomics instruments such as Bruker TimsTOF and/or Thermo Orbitraps
Strong oral and written communication skills and the ability to work independently and as part of a team with a track record of scientific publications in peerreviewed journals.

Nice-to-Have

Deep understanding of biological systems, including pathway regulation, posttranslational modification, molecular and cell biology, etc.
Familiarity with how machine learning can be applied to MSderived proteomics data
Comfortable learning new API's and tools as needed. Experience working in cloudbased and mixed computing environment using proteomics data.
Worked on Multiomics Datasets

Other Job Details:

Must have work authorization in the US
Work Location Assignment: On Premise.

Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act

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Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.

Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.

If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.

Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development