Research Scientist - Boston, United States - Massachusetts General Hospital(MGH)

Mark Lane

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Mark Lane

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Description

Research Scientist

GENERAL SUMMARY/OVERVIEW:


The Wein laboratory investigates molecular mechanisms used by parathyroid hormone to exert its function in target cells in bone and other tissues.

We employ wide-ranging techniques to study parathyroid hormone signaling in vitro and in vivo.

These studies will lead to an improved understanding of skeletal responses to PTH, and have important implications for the treatment of osteoporosis, dental disease, and chronic kidney disease.


Responsibilities comprise, but are not limited to:

  • Animal husbandry to track the status of a complex colony of genetically-modified mice
  • Mouse necropsy and collection of dentalrelevant tissues for histopathology and primary cell culture
  • Histopathology analysis of jaw and dental tissues
  • Immunohistochemistry and in situ hybridization of jaw and dental tissues
  • RNA isolation, RTqPCR
  • Protein isolation, immunoblotting
  • Keeping an active and accurate laboratory notebook
  • Regular meetings with members of research team to present and discuss data
  • Manuscript writing, figure preparation
  • Present data at local and international scientific meetings

EDUCATION/EXPERIENCE:

  • Master's Required. PhD, MD, DDS, DMSc, or MD/PhD in biomedical sciences preferred.
  • Minimum of 3 years of research experience (inclusive of graduate studies) required.

SKILLS/ ABILITIES/ COMPETENCIES REQUIRED:

  • Demonstrated ability to work independently as well as in a group environment.
  • Strong research design and analytical skills, with demonstrated ability to problem solving.
  • Strong organizational and communication skills.
  • Demonstrated analytical skills to problem solve effectively.
  • Experience in cell culture, molecular/cell biology, biochemistry, and mouse models of skeletal and mineral metabolism disease.

WORKING CONDITIONS:

  • Duties will be performed in a research laboratory.
  • No direct patient contact will occur.
  • Must be willing to work with mice.
  • Flexible work hours conducted over a fortyhour work week.

EEO Statement
Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.


Primary Location MA-Boston-MGH Main Campus


Work Locations MGH Main Campus 55 Fruit Street Boston 02114


Job Technician/Technologist/Scientist


Organization Massachusetts General Hospital(MGH)


Schedule Full-time


Standard Hours 40


Shift Day Job


Posted Shift Description M-F 8:30AM-5:00PM


Employee Status Regular


Recruiting Department MGH Endocrine


Job Posting May 22, 2024

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